DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssh and Dusp5

DIOPT Version :9

Sequence 1:	NP_733063.1	Gene:	ssh / 42986	FlyBaseID:	FBgn0029157	Length:	1193	Species:	Drosophila melanogaster
Sequence 2:	NP_598262.2	Gene:	Dusp5 / 171109	RGDID:	620854	Length:	384	Species:	Rattus norvegicus

Alignment Length:	173	Identity:	54/173 - (31%)
Similarity:	84/173 - (48%)	Gaps:	27/173 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   385 PTKIFEHVYLGSEWNASNLEELQKNGVRHILNVTREIDNFFPGTFEYFNVRVYDDEKTNLLKYWD 449
            |.:|...:||||.::||..|.|....:..:|||:|...........|..:.|.|....::..::.
  Rat   179 PVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACTTHLHYKWIPVEDSHTADISSHFQ 243

  Fly   450 DTFRYITRAKAEGSKVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFLN 514
            :...:|...:.||.||||||:.|||||.::.:||.||..|:..::|.|::|:|||.:.||..|:.
  Rat   244 EAIDFIDCVREEGGKVLVHCEAGVSRSPTICMAYLMKTKQFRLKEAFEYIKQRRSVVSPNFGFMG 308

  Fly   515 QLETYSGMLDAMKNKEKLQRSKSETNLKSTKDARLLPGSEPTP 557
            ||..|                          ::.:|| |.|||
  Rat   309 QLLQY--------------------------ESEILP-STPTP 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166
		DEK_C	328..379	CDD:285919
		DSPc	385..519	CDD:238073	47/133 (35%)
Dusp5	NP_598262.2	DSP_MapKP	5..140	CDD:238723
		Nuclear localization signal. /evidence=ECO:0000255	53..74
		DSP_DUSP5	179..316	CDD:350487	48/162 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820