DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssh and DUSP19

DIOPT Version :9

Sequence 1:	NP_733063.1	Gene:	ssh / 42986	FlyBaseID:	FBgn0029157	Length:	1193	Species:	Drosophila melanogaster
Sequence 2:	NP_543152.1	Gene:	DUSP19 / 142679	HGNCID:	18894	Length:	217	Species:	Homo sapiens

Alignment Length:	178	Identity:	62/178 - (34%)
Similarity:	93/178 - (52%)	Gaps:	24/178 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   361 DMDLGEYKSFIDAEMLVILGQMDAPTKIFEHVYLGSEWNASNLEELQKNGVRHILNVTREIDNFF 425
            |:.:|..|.::      :||..||               |.:|:.|:||.|.|||||...::|.|
Human    63 DLQVGVIKPWL------LLGSQDA---------------AHDLDTLKKNKVTHILNVAYGVENAF 106

  Fly   426 PGTFEYFNVRVYDDEKTNLLKYWDDTFRYITRAKAEGSKVLVHCKMGVSRSASVVIAYAMKAYQW 490
            ...|.|.::.:.|..:||:|.|:.:.|.:|..||.:...|||||..||||:|::||.:.|.:.|.
Human   107 LSDFTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQT 171

  Fly   491 EFQQALEHVKKRRSCIKPNKNFLNQLETYSGMLDAMKNK-EKLQRSKS 537
            .|..|...||..|..|.||..|:.||.||....::  || :::|.:.|
Human   172 SFTSAFSLVKNARPSICPNSGFMEQLRTYQEGKES--NKCDRIQENSS 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166
		DEK_C	328..379	CDD:285919	3/17 (18%)
		DSPc	385..519	CDD:238073	49/133 (37%)
DUSP19	NP_543152.1	DSP_DUSP19	65..201	CDD:350373	56/156 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820