Protein Alignment ssh and DUSP10

DIOPT Version :9

• Sequence 1: NP_733063.1
• Gene: ssh / 42986
• FlyBaseID: FBgn0029157
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: NP_009138.1
• Gene: DUSP10 / 11221
• HGNCID: 3065
• Length: 482
• Species: Homo sapiens
• Alignment Length: 516
• Identity: 114/516 - (22%)
• Similarity: 201/516 - (38%)
• Gaps: 117/516 - (22%)

  Fly    48 LVLALKDIPPLTQSERRLSTDSTRSSNSTQSNNSD--------IQLHLQSMFYLLQREDTLKMAV 104
            :|:||.  .|:...:..|..||:...::...:||.        :.|...::.|:
Human    10 VVVALS--RPVRPQDLNLCLDSSYLGSANPGSNSHPPVIATTVVSLKAANLTYM----------- 61

  Fly   105 KLESQRSNRTRYLVIASRSCCRSGTSDRRRHRIMRHHSVKVGGSAGTKSSTSPAVPTQRQLSVEQ 169
             ..|..|.|:.....:|.|||...|.|:..   .........|:..|...||...|..:.::
Human    62 -PSSSGSARSLNCGCSSASCCTVATYDKDN---QAQTQAIAAGTTTTAIGTSTTCPANQMVN--- 119

  Fly   170 TATEASSKCDKTADKENATAAGDNKNTSGMEESCLLGIDCN----ERTTIGLVVP------ILAD 224
                                  :|:||..:..|..:|...:    :..:|.::.|      :...
Human   120 ----------------------NNENTGSLSPSSGVGSPVSGTPKQLASIKIIYPNDLAKKMTKC 162

  Fly   225 TTIHLDGDGGFSVKV-----YEKTHIFKPVSV---------QAMWSALQTLHKVSKKARENNFYA 275
            :..||...|...:..     |.|:||...|.:         :.....:..|..:|.:..:::|
Human   163 SKSHLPSQGPVIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSF-- 225

  Fly   276 SGPSHDWLSSYERRIESDQSCLNEWNAMDALESRRPPS-PDAIRNKPPEKEETES-VIKMKLKAI 338
                        :||.|.:..:.:.|..:  .||..|| |..|..:..::|..|. |:|..|.:.
Human   226 ------------KRIFSKEIIVYDENTNE--PSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSF 276

  Fly   339 MM--------SVDLDEVTSKYIRG---RLEEILDMDLGEYKSFIDAEMLVILGQMDAPTKIFEHV 392
            ..        |:.|.|  .:.:.|   ....:|...:.......:||:          |.|...:
Human   277 KQNHENLCDNSLQLQE--CREVGGGASAASSLLPQPIPTTPDIENAEL----------TPILPFL 329

  Fly   393 YLGSEWNASNLEELQKNGVRHILNVTREID--NFFPGTFEYFNVRVYDDEKTNLLKYWDDTFRYI 455
            :||:|.:|.:|:.:|:..:.:::|||..:.  ::..|.|.|..:...|..|.||.:|:::.|.:|
Human   330 FLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFI 394

  Fly   456 TRAKAEGSKVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFLNQL 516
            ..|...|..:|:||:.||||||::||||.||..:.....|.:.||.:|..|.||.||:.||
Human   395 EEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQL 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166	49/296 (17%)
		DEK_C	328..379	CDD:285919	11/62 (18%)
		DSPc	385..519	CDD:238073	49/134 (37%)
DUSP10	NP_009138.1	DSP_MapKP	149..284	CDD:238723	27/150 (18%)
		Interaction with MAP kinases	199..215		1/15 (7%)
		DSPc	321..459	CDD:238073	50/145 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2281
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850