DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssh and dusp10

DIOPT Version :9

Sequence 1:	NP_733063.1	Gene:	ssh / 42986	FlyBaseID:	FBgn0029157	Length:	1193	Species:	Drosophila melanogaster
Sequence 2:	XP_031758376.1	Gene:	dusp10 / 101731867	-ID:	-	Length:	477	Species:	Xenopus tropicalis

Alignment Length:	508	Identity:	119/508 - (23%)
Similarity:	196/508 - (38%)	Gaps:	106/508 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LVLALKDIPPLTQSERRLSTDSTRSSNSTQSNNSDIQLHLQSMFYLLQREDTLKMAVKLESQRSN 112
            :::||.  .|:......|..||:...:|:..::|...|...|:..|    :...:.....|..|.
Frog    10 VIVALS--RPVRPQVLNLCLDSSYFESSSILSDSHKSLLSTSVVCL----NAANLTYMPSSTSSA 68

  Fly   113 RTRYLVIASRSCCRSGTSDRRRHRIMRHHSVKVGGSAGTKSSTSPAVPTQRQLSVEQTATEASSK 177
            |:.....:|.|||...:.|                    |.|.|.||.:....|.....:.:||.
Frog    69 RSLGCGCSSASCCTVASYD--------------------KDSQSQAVSSTTITSGVSGPSASSSA 113

  Fly   178 CDKTADKENATAAGDNKNTSGMEESCLLGIDCNERTTIGLVVP------ILADTTIHLDGDGGFS 236
            .....:.||:.|.    ::||   |.:.|. ..:.:.|.::.|      |...|..||...|...
Frog   114 NQMVNNNENSGAL----SSSG---SPISGA-TKQFSNIKIIYPNDLAKKISKCTKTHLPNQGPVI 170

  Fly   237 VKV-----YEKTHIFKPVSVQAMWSALQTLHKVSKKARENNFYASGPSHDWLSSYERRIESDQ-- 294
            :..     |.|:||...|.:...       .|:|:                     ||::..:
Frog   171 IDCRPFMEYNKSHIQGAVHINCS-------DKISR---------------------RRLQQGKIT 207

  Fly   295 -----SCLNEWNAMDALESRRPPSPDAIRNKPPEKEETESVIKMKLKAIMMSVDLDEVTSKYIRG 354
                 ||....::...:.|:.....|...|:|.....|:     .|..::.|:..:......::|
Frog   208 VLDLISCREGKDSFKRIFSKEIIVYDDNTNEPSRVMPTQ-----PLHTVLESLKREGKEPLVLKG 267

  Fly   355 RL-------EEILD--MDLGEYKSFIDAEMLVILGQMDAP----------TKIFEHVYLGSEWNA 400
            .|       |.:.|  :.|.:......|..:.|......|          |.|...:|||:|.:|
Frog   268 GLSSFKQNHESLCDNSLQLQDCSDGGGASAVSITLPQSIPTTPDIENAELTPILPFLYLGNEHDA 332

  Fly   401 SNLEELQKNGVRHILNVTREID--NFFPGTFEYFNVRVYDDEKTNLLKYWDDTFRYITRAKAEGS 463
            .:||.:|...:.:|:|||..:.  ::..|.|.|..:...|..|.||.:|:::.|.:|..|...|.
Frog   333 QDLETMQTRNISYIVNVTTHLPLYHYEKGVFNYKRLPATDSNKQNLRQYFEEAFEFIDEAHQCGK 397

  Fly   464 KVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFLNQL 516
            .:|:||:.||||||::||||.||..:.....|.:.||.:|..|.||.||:.||
Frog   398 ALLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQL 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166	53/282 (19%)
		DEK_C	328..379	CDD:285919	8/59 (14%)
		DSPc	385..519	CDD:238073	53/144 (37%)
dusp10	XP_031758376.1	DSP_MapKP	145..280	CDD:238723	27/167 (16%)
dusp10	XP_031758376.1	DSP_DUSP10	317..468	CDD:350415	52/134 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010