Protein Alignment ssh and ssh2

DIOPT Version :9

• Sequence 1: NP_733063.1
• Gene: ssh / 42986
• FlyBaseID: FBgn0029157
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: XP_004911756.2
• Gene: ssh2 / 100488169
• XenbaseID: XB-GENE-993093
• Length: 1419
• Species: Xenopus tropicalis
• Alignment Length: 1519
• Identity: 412/1519 - (27%)
• Similarity: 596/1519 - (39%)
• Gaps: 464/1519 - (30%)

  Fly     6 CSLPDDILIFSLTPRDGESEDDEGNSKGNDRSECFFAGKGTALVLALKDIPPLTQSERRLSTDST 70
            |...:|..:|:.| .:.:|.::|..|:....||.|...||.||.|           .|...:.:.
 Frog    34 CCQYEDTELFNGT-NEADSGEEECRSQPRSISESFLTVKGAALFL-----------PRGNGSSTP 86

  Fly    71 RSSNSTQSNNSDIQLHLQSMFYLLQREDTLKMAVKLESQRSNRTRYLVIASRSCCRSGTSDRRRH 135
            |.|:....:..|:|.|||:||.||:.||.:::||||||...|||||:|:.|    .:|..|
 Frog    87 RISHRRNKHAGDLQQHLQAMFTLLRPEDNIRLAVKLESTYQNRTRYMVVVS----TNGRQD---- 143

  Fly   136 RIMRHHSVKVGGSAGTKSSTSPAVPTQRQLSVEQTATEASSKCDKTADKENATAAGDNKNTSGME 200
                                                                           .|
 Frog   144 ---------------------------------------------------------------TE 145

  Fly   201 ESCLLGID--CNERT--TIGLVVPILADTTIHLDGDGGFSVKVYEKTHIFKPVSVQAMWSALQTL 261
            ||.:||:|  .|:.:  |:|||:|:.:||.|||||||||||....:.||||||||||||||||:|
 Frog   146 ESIVLGMDFASNDSSMCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSL 210

  Fly   262 HKVSKKARENNFYASGPSHDWLSSYERRIESDQSCLNEWNAMDALESRRPPSPDAIRNKPPEKEE 326
            ||..:.||.||:|.......|:|.||..|.|||..:||||||..::|.|..||....:.|.|:|.
 Frog   211 HKACEIARINNYYPGSLFLTWVSYYESHINSDQCSINEWNAMQDVQSHRSDSPVLFTDVPTERER 275

  Fly   327 TESVIKMKLKAIMMSVDLDEVTSKYIRGRLEEILDMDLGEYKSFIDAEMLVILGQMDAPTKIFEH 391
            ||.:||.||:.|||..||:.:|||.||..||..:..:|.|:|.|||.||:|||||||:||:||:|
 Frog   276 TERLIKSKLREIMMQKDLENITSKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTEIFDH 340

  Fly   392 VYLGSEWNASNLEELQKNGVRHILNVTREIDNFFPGTFEYFNVRVYDDEKTNLLKYWDDTFRYIT 456
            |:|||||||||||:||..|||:||||||||||||||.|||.|:||||:|.|:||.||:|||::|:
 Frog   341 VFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGLFEYHNIRVYDEEGTDLLAYWNDTFKFIS 405

  Fly   457 RAKAEGSKVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFLNQLETYSG 521
            :||..|||.|||||||||||||.|||||||.|.|...:|.::||:||:..|||.:|:.|||.|.|
 Frog   406 KAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAFDYVKERRTVTKPNPSFMKQLEEYQG 470

  Fly   522 MLDAMKNK-EKLQRSKSETNLKSTKDARLLPGSEPTPLIQALNQAKSKSTGEAGVTPDGEEEDGS 585
            :|.|.|.: .||.||.|:::|..        ..||... ..|..:|...|..|....|.......
 Frog   471 ILLASKQRHNKLWRSHSDSDLSD--------HHEPVGK-TGLEMSKKDITSSAEQLSDTHHSFSL 526

  Fly   586 RMHRR----------SIAQKSQRRM-------------------------VRRSSSTSPKTQTAV 615
            ..|..          ::..::|.|.                         .|..|..:......:
 Frog   527 GPHTENCNPDCPMDSTLYNETQARFEFTSCDFHTEQIEDILNLNTMNGCPSRCCSDDTILDNCRI 591

  Fly   616 VTKQQSQSMENLT-----PERSVAEEPKNMRFPGSNGENYSVTQNQVLHIQ---------KHTP- 665
            |.|..:|:.|:.|     |:.::.:..|:...|..|..:        ||::         :.:|
 Frog   592 VEKDLTQNPESFTVPGQLPDLTLEDMEKDALKPEVNCHH--------LHLEGLNSDFRDLQESPD 648

  Fly   666 -LSVRTRIHDLEAHRADQLPQQPVWTSLTKLI-TQTSHLGKSVSGSSSGNIDSRRDSSC------ 722
             ||:.::..:|...|.|.|      ::|.|.: ....:..:|.|.:.:..:.|.::|:.
 Frog   649 QLSMTSQSEELNGDRIDFL------SALEKFVELSQENRPRSCSTTRADEVSSVKNSALKASWPE 707

  Fly   723 SDVFSSQVDSVFAKDEGEKRQRRKTHSWTESLGP---SGGIVLDPTPQQQKQQSNAILRPRGTRQ 784
            :.|:.|.||:.....:|...|..:..| |:...|   |..||.:|.|:...:.:.::
 Frog   708 TPVYDSHVDNQRISSDGSTSQTSEDSS-TDEEQPKEISEQIVQEPLPKSHSENAISV-------- 763

  Fly   785 RELPSRHASWGSGDNRCCLPQRTSSGSYYDSNRNT-----------------------TAIFEGV 826
            :|:.:...|:..|..:|.....|.|.......|||                       :|:.:
 Frog   764 KEIITEIESFNQGAGQCQQKPDTQSSQSQTPKRNTIHDLPHDFALDQENNHRQEPSDRSALLQ-- 826

  Fly   827 IQDLKRSSNCNVIEGVAVAVEPIVGVGE----------------GTVKRTKQKLEE--------- 866
             .|..|.|.....:|..|:.|......|                |:|:|...:|||
 Frog   827 -NDKLRDSKVATWDGNPVSQENCENSNEANDYQELSSQAHKWCAGSVRRATLELEERLRQEQEQQ 890

  Fly   867 -STSLKKRCQEESQELLLEAVDAGQRRCPSLYRSASSAHSPRQRQPLRC------NSEE------ 918
             |.:|..|...::...:.:....|:.. .:|..||...|...::..|:.      ||.|
 Frog   891 YSATLPTRKNSKNDSAVGDTAPKGKLE-DTLLDSAHGDHEKDRKNQLKIAESTEPNSSEPCADSS 954

  Fly   919 ---------LMH-----TSDIENKNTT------------------------------------PG 933
                     |:.     .|:|:.|.||                                    |.
 Frog   955 SSQISEPQCLLSKPESPVSEIKLKETTNEHGELHSLESVERKIEPIQLPKRIEIIEYSIGIKSPN 1019

  Fly   934 DHE-------ATVVLRVQGQTL----------------------------ADDQRISGNVQI--- 960
            |:|       ||:     |:.|                            ||...:|...::
 Frog  1020 DNELSQCEDGATL-----GEVLIETKTSMILSPEMPFKEIPETETDNSLHADSLHLSETCELGSP 1079

  Fly   961 -----LKQNFEAKAGVVGTGGGGGGGTAAGSGSSSTI------ATSVSAVAGACSANPGKKTTSH 1014
                 |....|....|.........|.:......||:      :.|::.|...||:     |...
 Frog  1080 SVSFSLTSQCEEHNSVNIPVPSACTGPSMQPDLLSTLYPYTQGSISLTGVTEECSS-----TDED 1139

  Fly  1015 QSLPSSPVAQHANHVSAASNSNSSASNSSDSSVSENCDRNVK----------------------- 1056
            .|.|.|  ...:.|..|..:.|......:||::|:....::.
 Frog  1140 FSKPFS--CTESYHTDAFEDFNEMMHRETDSALSQCSSEDLNLISTVSANILEIREVLDIPPLSF 1202

  Fly  1057 GLVHKYQTTTSCSSQAAATPTVAC-------APLPPAG--TASNISHSCSTTTTTSFKQRPLSYY 1112
            |..|  .::|.......:.|.|..       |.:..||  |.|.:..|.|.......:.......
 Frog  1203 GFAH--SSSTDSIKDLGSNPGVVKQKAKEIEARIRQAGLTTPSQMKRSASLAKLGCLELSKDDLS 1265

  Fly  1113 DRSLSNRSTHDYSD--------------------SRPPPAPVRV----SHSSNVQHQQQQ----- 1148
            :|...:..:..|.|                    |:.||..:.:    ..|...:|..:|
 Frog  1266 ERESVSSDSQTYPDLLLSSLRVVPGSFEISPDIKSQDPPEKLCILSTQVESEPTKHFVEQIKTEE 1330

  Fly  1149 ----------------------QQQLQPEQHQQ--------------------QVQIRRLAQHGK 1171
                                  ||.|.|....:                    .|.|....:||:
 Frog  1331 CVVQSKPVEKPLVQFAKDFDSTQQGLSPSSESELTVSEGGSPMQSLVLGTSVPLVSISPKHEHGR 1395

  Fly  1172 THPLSRL--SAPKTGFNTAAYNTM 1193
            ||||.||  :..|.......||||
 Frog  1396 THPLRRLKKTNEKKRTTNPLYNTM 1419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166	105/295 (36%)
		DEK_C	328..379	CDD:285919	26/50 (52%)
		DSPc	385..519	CDD:238073	93/133 (70%)
ssh2	XP_004911756.2	SSH-N	43..262	CDD:212166	107/301 (36%)
		DEK_C	276..328	CDD:400903	27/51 (53%)
		DSP_slingshot_2	331..474	CDD:350417	98/142 (69%)
		MDN1	<634..974	CDD:227596	63/358 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	200	1.000	Domainoid score	I2986
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	473	1.000	Inparanoid score	I1464
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm49159
Panther	1	1.100	-	-	LDO	PTHR45864
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2281
SonicParanoid	1	1.000	-	-		X2719
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.100