DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssh and dusp22a

DIOPT Version :9

Sequence 1:	NP_733063.1	Gene:	ssh / 42986	FlyBaseID:	FBgn0029157	Length:	1193	Species:	Drosophila melanogaster
Sequence 2:	XP_002936144.2	Gene:	dusp22a / 100485576	XenbaseID:	XB-GENE-5831311	Length:	209	Species:	Xenopus tropicalis

Alignment Length:	202	Identity:	55/202 - (27%)
Similarity:	93/202 - (46%)	Gaps:	36/202 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   386 TKIFEHVYLGSEWNASNLEELQKNGVRHILNVTREIDNFFPGTFE--YFNVRVYDDEKTNLLKYW 448
            |||.:.:|||:..::.:...|.:||:|||::|.   :|..|...|  |..:...|....||::::
Frog     6 TKIVDGLYLGNIRDSEDKATLNRNGIRHIVSVH---NNAKPLLQEMTYLCISASDSSSQNLIQHF 67

  Fly   449 DDTFRYITRAKAEGSKVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFL 513
            ....::|...:..|...||||..|||||.::::||.|....:.:.:.|..|:..||.:.||..|.
Frog    68 KQCIKFIHECRLHGGGCLVHCLAGVSRSTTILVAYLMTVTNFGWDECLSAVRSVRSYVGPNFGFQ 132

  Fly   514 NQLETYSGML--------------DAMKNKEKLQR--SKSETNLKSTKDARLLPGSEPTPLIQAL 562
            .||:.|...|              :...:::|:|:  :|.|               |...|.|..
Frog   133 QQLQEYEMTLVKEYRLWLRQEYGRNPFNDQDKVQQLIAKQE---------------EKEQLRQVQ 182

  Fly   563 NQAKSKS 569
            ||..::|
Frog   183 NQWINRS 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166
		DEK_C	328..379	CDD:285919
		DSPc	385..519	CDD:238073	43/134 (32%)
dusp22a	XP_002936144.2	PTP_DSP_cys	2..150	CDD:421693	45/146 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920