Protein Alignment ssh and dusp8b

DIOPT Version :10

• Sequence 1: NP_733063.1
• Gene: ssh / 42986
• FlyBaseID: FBgn0029157
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: XP_002665347.3
• Gene: dusp8b / 100330259
• ZFINID: ZDB-GENE-120914-3
• Length: 499
• Species: Danio rerio
• Alignment Length: 558
• Identity: 131/558 - (23%)
• Similarity: 213/558 - (38%)
• Gaps: 99/558 - (17%)

  Fly   326 ETESVIKMKLKAIMMSVDL-------DEVTSKYIRGRLEEILDMDLGEYKSFIDAEMLVILGQMD 383
            |:|..:||:::.|....||       .....:....:...||.:.|.:     ....:..:|
Zfish     3 ESEMRLKMRVRRIKEGRDLRGGFAAFSSCFPELCENKPASILPLSLSQ-----PCLPVANIG--- 59

  Fly   384 APTKIFEHVYLGSEWNASNLEELQKNGVRHILNVTREIDN-FFPGTFEYFNVRVYDDEKTNLLKY 447
             ||:|..|:||||:.:..|.|.:.:||:.::||.:..... .|.....:..:.|.|.....||.:
Zfish    60 -PTRILPHLYLGSQRDVLNKEVMSQNGITYVLNASNTCPKPDFISENHFMRIPVNDSYCEKLLPW 123

  Fly   448 WDDTFRYITRAKAEGSKVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNF 512
            .:.|..:|.:||....:|:|||..|:||||::.|||.||........|...||.||..|.||.||
Zfish   124 LEKTNEFIDKAKVSNCRVIVHCLAGISRSATIAIAYIMKTMGLSSDDAYRFVKDRRPSISPNFNF 188

  Fly   513 LNQLETYSGMLDAMKNKEKLQRSKSETNLKSTKDARLLPGSEPTPLIQALNQAKSKSTGEAGVTP 577
            |.||..:...|:..|:.....|.::.| :|...:.|.:...:          .::..|.|..|.|
Zfish   189 LGQLLEFERGLEMKKSLPCPIRMEAST-VKEVTEIRKMENDD----------QRTSQTTEITVNP 242

  Fly   578 DGE---EEDGSRMHRRSIAQKSQRRMVRRSSSTSPKTQTAVVTKQQSQSMENLTPERSVAEEPKN 639
            ...   ::|.|.:| .|..:..|.:.::.|.|...|      :...|....|.:|.......||.
Zfish   243 PSPTSLQKDLSSLH-LSTEKILQNKRLKCSFSLDIK------SVYSSSPNHNSSPNSDSENTPKI 300

  Fly   640 MRFPGSNGENYSVTQNQV-----LHIQKHTPLSVRTRIHDLEAHRADQLPQQPVWTSLTKLITQT 699
            .|.......| .|.|:|.     :..::.:..|:...:....:...||..:.....||.
Zfish   301 CRIDNLKNTN-GVGQSQCMIATQIGFKRLSATSLSLNLKQENSGLQDQNCENNKKASLL------ 358

  Fly   700 SHLGKSVS-----GSSSGNIDSRRDSSC-----SDVFSSQVDSVFAKDEGEKRQRRKTHSWTESL 754
              ||||.|     ||:..:........|     :::..|...:.|..        ..|:|.....
Zfish   359 --LGKSASWTTHRGSNQASTPITPTGDCPWFLAANLAPSGTSAHFGS--------TSTYSAYSCS 413

  Fly   755 GPSGGIVLDPTP---QQQKQQSNAILRPRGTRQRELPSRHASW---GSGDNRCCLPQ------RT 807
            |.||    :|.|   |:.|.|.::         ||:    :||   |.....|.:.|      |.
Zfish   414 GQSG----NPKPGAYQRDKTQGDS---------REI----SSWLDDGKTQIVCGISQVDTKYKRR 461

  Fly   808 SSGSYYDSNRNTTAIFEGVIQDLKRSSNCNVIEGVAVA 845
            |....::...:||...|......|:||....:|.:.|:
Zfish   462 SCQMEFEDGMSTTQSGEDFGNLGKQSSFSGSMEVIEVS 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166
		DEK_C	326..379	CDD:462592	10/59 (17%)
		DSP_slingshot	385..523	CDD:350363	50/138 (36%)
dusp8b	XP_002665347.3	RHOD	<13..36	CDD:444705	3/22 (14%)
		PTP_DSP_cys	49..199	CDD:475123	51/158 (32%)