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Protein Alignment Osbp and OSBPL2

DIOPT Version :9

Sequence 1:	NP_477271.1	Gene:	Osbp / 42985	FlyBaseID:	FBgn0020626	Length:	784	Species:	Drosophila melanogaster
Sequence 2:	NP_653081.1	Gene:	OSBPL2 / 9885	HGNCID:	15761	Length:	480	Species:	Homo sapiens

Alignment Length:	561	Identity:	186/561 - (33%)
Similarity:	268/561 - (47%)	Gaps:	133/561 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   273 EMEFFDAEEHGYSGSGRSPESSDCERGTFILKMHKRRSSSEDQVEGHLEGSSSESDEQKRTVQTV 337
            |.|||||.. |:        .||...|.|        |.:..:|.|.::..:|:::
Human     4 EEEFFDAVT-GF--------DSDNSSGEF--------SEANQKVTGMIDLDTSKNN--------- 42

  Fly   338 QQVCLVSAPRVASGGQGDDDDDVDKALPAKESTDSIYGRNWNPDLIKKRRDRVPDK--PNHPISL 400
                     |:...|:          .|::|:.            |:|.|..:|..  .....|:
Human    43 ---------RIGKTGE----------RPSQENG------------IQKHRTSLPAPMFSRSDFSV 76

  Fly   401 WGIMKNCIGKDLSKIPMPINFNEPLSMLQRLVEDYEYTEILDYAATCQDE-CEQLAYIAAFTVSA 464
            |.|:|.|:|.:||||.|||.||||||.|||:.|..|:..:: :.|:||.: .|::..:|||.|||
Human    77 WTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLI-HRASCQPQPLERMQSVAAFAVSA 140

  Fly   465 YATTTNRTGKPFNPLLGETYECDRMDDYGWRCLAEQVSHHPPVAALHCESKNWTCWQEFSMTS-- 527
            .|:...|||||||||||||||..| :|.|:|.::||||||||::|.|.|..|    .:|....
Human   141 VASQWERTGKPFNPLLGETYELIR-EDLGFRFISEQVSHHPPISAFHSEGLN----HDFLFHGSI 200

  Fly   528 ----KFRGKYVQINPLGGVYVQFPNSGRRYSWRKVTTTVNNIIVGKLWVDQHGEMEIRGSQAAEG 588
                ||.||.|:..|.|.:.::.......|:|...|..|:|:|:||||::|:|.:||...:.  |
Human   201 YPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRT--G 263

  Fly   589 HKCILNFIPYSYFSRDVQRSVKGVVMNKDNEVKWVVRGTW-DMKIEIAPVL-------------- 638
            |||:|:|.|...|.:::.: |:|.:.:|:.:..:::.|.| :....|.||.
Human   264 HKCVLHFKPCGLFGKELHK-VEGHIQDKNKKKLFMIYGKWTECLWGIDPVSYESFKKQERRGDHL 327

  Fly   639 ----------KTSGSVSSPTYTTGE-------FKLAWRRRPAPPDSDKFYNFTTLACQLNEEEEG 686
                      |....|:.......|       .||.||....||:|.:.||||:....|||.|.|
Human   328 RKAKLDEDSGKADSDVADDVPVAQETVQVIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETG 392

  Fly   687 ----VAPTDSRLRPDQRLMEQGDWDESNKEKLRLEEKQRTERRRRENEAEEAAAEGRPYPAYEPM 747
                :.|||.|||||.|.||.|:.|.:::||.|||||||..||.|..|..|          ::..
Human   393 MEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARRERAKEEAE----------WQTR 447

  Fly   748 WFKREKEEGSEEYV----HVFKNTYWEAKAAQNFEGCPDIY 784
            ||    ..|:..|.    .::...|:|    :||..|||||
Human   448 WF----YPGNNPYTGTPDWLYAGDYFE----RNFSDCPDIY 480

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.