Protein Alignment Osbp and ORP1A

DIOPT Version :10

• Sequence 1: NP_477271.1
• Gene: Osbp / 42985
• FlyBaseID: FBgn0020626
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_180659.2
• Gene: ORP1A / 817653
• AraportID: AT2G31020
• Length: 778
• Species: Arabidopsis thaliana
• Alignment Length: 839
• Identity: 253/839 - (30%)
• Similarity: 386/839 - (46%)
• Gaps: 206/839 - (24%)

  Fly     1 MTDAAGNALAEKGLPEMKGWLLKWTNYIKGYQRRWFVLSKGVLSYY------------------- 46
            :.|.|||::|        |.|.||.||.||::.|||||..||||||
plant    83 INDIAGNSIA--------GILYKWVNYGKGWRPRWFVLQDGVLSYYKIKGPDKIVVIHETEKGSR 139

  Fly    47 -----------RNQ-----SEINHTCR----GTISLHGALIH--TVDSCTFVISNGGTQTFHIKA 89
                       ||:     :..||..|    |.:.|..:.|.  ..|...|.|.. ||:..|::|
plant   140 VIGEESTRMISRNKRHAATNNTNHQLRRKPFGEVHLKVSSIRESRSDDKRFSIFT-GTKRLHLRA 203

  Fly    90 GTEVERQSWVTALELAKAKAIRAIECEEEEETETAHVVPSQEISSVVRDLTDRLESMRTCYDLIT 154
            .|..:|::|:.||:..|....|...||        .:.|:..:...:..|..||          .
plant   204 ETREDREAWIEALQAVKDMFPRMSNCE--------LMAPTNNLDISIEKLRLRL----------V 250

  Fly   155 KHGAALQRALNDLE---TNEEESLGSRTKIVNERATLFRITSNAMINAGNDYLHTAEAQGHKWSK 216
            :.|.: :.|:.|.|   .:|..::.|:..::.::..|
plant   251 EEGVS-ESAIQDCEQITRSEFSAIQSQLLLLKQKQWL---------------------------- 286

  Fly   217 MLHHEREQRQRLEEIIEQMAKQQSQMEQAAVLVRQNKPVSSTSGAGTAGSLVT-SDEEMEFFD-A 279
                       |.:.:.|:..::..:|...|...|.:     :|.|.:...:: ||::.|.|| |
plant   287 -----------LIDTLRQLETEKVDLENTVVDETQRQ-----AGNGDSEETISESDDDNEQFDEA 335

  Fly   280 EEHGYSGSGRSPESSDCERGTFILKMHKRRSSSEDQVEGHLEGSSSESDEQKRTVQTVQQVCLVS 344
            ||          |...|:         ...|||...:......||..||:...|
plant   336 EE----------EMDTCD---------SLSSSSFKSIGSVFRTSSFSSDDDGLT----------- 370

  Fly   345 APRVASGGQGDDDDDVDKALPAKESTDSIYGRNWNPDLIKKRRDRVPD--KPNHPISLWGIMKNC 407
                  .|...::||||.::       ...|.|: |.:  |||.::||  :....:|||.::|:.
plant   371 ------NGFESENDDVDPSI-------KTIGFNY-PHV--KRRKKLPDPVEKEKSVSLWSMIKDN 419

  Fly   408 IGKDLSKIPMPINFNEPLSMLQRLVEDYEYTEILDYAATC---QDECEQLAYIAAFTVSAYATTT 469
            |||||:|:.:|:.||||||.||:..||.||:.:||.|:..   .:...::..:|||.||.||:|.
plant   420 IGKDLTKVCLPVYFNEPLSSLQKCFEDLEYSYLLDQASEWGKRGNNLMRILNVAAFAVSGYASTE 484

  Fly   470 NRTGKPFNPLLGETYECDRMDDYGWRCLAEQVSHHPPVAALHCESKNWTCWQEFSMTSKFRGKYV 534
            .|..|||||:||||||.| ..|.|.|..:|:|||||.:.|.||:...|..|.:.::.|||.|:.:
plant   485 GRICKPFNPMLGETYEAD-YPDKGLRFFSEKVSHHPMIVACHCDGTGWKFWGDSNLKSKFWGRSI 548

  Fly   535 QINPLGGVYVQFPNSGRRYSWRKVTTTVNNIIVGKLWVDQHGEMEIRGSQAAEGHKCILNFIPYS 599
            |::|:|.:.:|| :.|....|.||||::.|:|:|||:.|.:|.|:|.|:..   :.|.|.|...|
plant   549 QLDPIGLLTLQF-DDGEIVQWSKVTTSIYNLILGKLYCDHYGTMKIEGNGE---YSCKLKFKEQS 609

  Fly   600 YFSRDVQRSVKGVVMNKDNEVKWVVRGTWDMKIEIAPVLKTSGSVSSPTYTTGEFKLAWRRRPAP 664
            ...|: ...|:|:|.:|:.:....:.|.||..|..  |:...|.|:       |..|.|:|...|
plant   610 MIDRN-PHQVQGIVEDKNGKTVARLFGKWDESIHY--VMVDQGKVN-------ESHLLWKRNKQP 664

  Fly   665 PDSDKFYNFTTLACQLNE----EEEGVAPTDSRLRPDQRLMEQGDWDESNKEKLRLEEKQRTERR 725
            .:..| ||.|.....|||    .:|.:.|||||||||||.:|:|:::..|.||||||::||..|.
plant   665 ENPTK-YNLTRFGITLNELTPGLKEKLPPTDSRLRPDQRYLEKGEYEMGNAEKLRLEQRQRQARE 728

  Fly   726 RRENEAEEAAAEGRPYPAYEPMWFKREKEEGSEEYVHVFKNTYWEAKAAQNFEGCPDIY 784
            .:|.             .::|.||::||  |||.|.::  ..||||:.:.:::.||||:
plant   729 MQER-------------GWKPKWFRKEK--GSETYRYI--GGYWEARDSGSWDDCPDIF 770

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Osbp	NP_477271.1	PH_OSBP_ORP4	17..113	CDD:270101	41/136 (30%)
		Oxysterol_BP	399..773	CDD:460126	152/380 (40%)
ORP1A	NP_180659.2	PH_ORP_plant	91..229	CDD:241448	42/146 (29%)
		Oxysterol_BP	411..759	CDD:460126	152/380 (40%)