Protein Alignment Osbp and osbpl6

DIOPT Version :9

• Sequence 1: NP_477271.1
• Gene: Osbp / 42985
• FlyBaseID: FBgn0020626
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_002935731.2
• Gene: osbpl6 / 734134
• XenbaseID: XB-GENE-987246
• Length: 902
• Species: Xenopus tropicalis
• Alignment Length: 958
• Identity: 259/958 - (27%)
• Similarity: 399/958 - (41%)
• Gaps: 298/958 - (31%)

  Fly     6 GNALAEKGLPEM-KGWLL---KWTNYIKGYQRRWFVLSKGVLSYYRNQSEINHTCRGTISLHGAL 66
            |.:..:|  ||. :|::|   ||.  :||:.:|:|||..|:|.|  ::|.|: |.:|  .|||
 Frog    48 GQSSVQK--PEKHEGFMLKKRKWP--LKGWHKRFFVLDNGILKY--SKSPID-TQKG--KLHG-- 101

  Fly    67 IHTVDSCTFVIS----------NGGTQTFHIKAGTEVERQSWVTAL------------------- 102
              ::|....|:|          :.....:|:|..:.....:||:.|
 Frog   102 --SIDVGLSVMSIKKKARRIDLDTEENIYHLKVKSPDTFDAWVSKLRHHRLYRQNEIVRSPRDAS 164

  Fly   103 ----------ELAKAKAIRAIE-----------------------CEEEEETETAHVVPSQEISS 134
                      |.:.|..:...|                       |...:....|.::.|:|:..
 Frog   165 LHMFPSTSTTESSPAANVTVPEGKVPQNNFLWQSPIPCSNSLPATCTTGQSKVAAWLLDSEEMDK 229

  Fly   135 VVRDL----TDRLESMRTCYDLITKHGAALQRALN-----DLETN--------EEESLGSRTKIV 182
            ...||    ::.:|..:..::|     ..|||..:     |::.|        :..|...|||.|
 Frog   230 CAEDLAQCQSNLIELSKLLHNL-----ELLQRTQSAPNFIDMQANCVDISKKDKRASRRWRTKSV 289

  Fly   183 NERATL---------------------------FRITSNAMINA---GNDY-------------- 203
            ::.|.:                           |:...:.:::|   .:||
 Frog   290 SKDAKIQLQVPHSASMSPVRLHASNPNLYADVEFQNPPSHVVDAMEFASDYTKLQEEFCLIAQKV 354

  Fly   204 -------LHTAEAQGHKWSKM-----------------------LHHEREQRQRLEEI------- 231
                   .:|...:..|..:|                       |:|..|.|.||..|
 Frog   355 HSLLKSAYNTIAIEKEKMKQMVSDQDYSGQSTQIARLRQSLSQALNHNSELRSRLNRIHTESVIS 419

  Fly   232 -----IEQMAKQQSQMEQAAVLVRQNKPVSSTSGAGTAGSLVTSDEEMEFFDAEEHGYSGSGRSP 291
                 :..:|......|...|.:..::.||:      .|.|..|:...|||||:|...|.|....
 Frog   420 DQVVSVNIIASSDESCEPMHVSLPLSQQVSN------EGRLSMSESVSEFFDAQEVLLSASSSEN 478

  Fly   292 ESSDCERGTFILKMHKRRSSSEDQVEGHLEGSSSESDEQKRTV----------QTVQQVCLVSAP 346
            |:||.|  ::|       |...|.:.   |.::|.:|...|.:          :|.::.|
 Frog   479 EASDDE--SYI-------SDVSDNIS---EDNTSVADNVSRQILNGELLGGAFRTGRRTC----- 526

  Fly   347 RVASGGQGDDDDDVDKALPAKESTDSIYGRNWNPDLIKKRRDRVPDKPNHPISLWGIMKNCIGKD 411
                             |||..                      ||..|  |:||.|::|.||||
 Frog   527 -----------------LPAPS----------------------PDTSN--INLWNILRNNIGKD 550

  Fly   412 LSKIPMPINFNEPLSMLQRLVEDYEYTEILDYAATCQDECEQLAYIAAFTVSAYATTTNRTG-KP 475
            |||:.||:..||||:.||.|.|:.||:|:||.||...|..|::|.||||.||.||:|..|.| ||
 Frog   551 LSKVSMPVELNEPLNTLQHLCEELEYSELLDKAAETDDPHERMALIAAFAVSGYASTYYRAGSKP 615

  Fly   476 FNPLLGETYECDRMDDYGWRCLAEQVSHHPPVAALHCESKNWTCWQEFSMTSKFRGKYVQINPLG 540
            |||:|||||||.| :|.|:|..:||||||||::|.||||||:..||:....:||.||.::|.|.|
 Frog   616 FNPVLGETYECIR-EDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPFG 679

  Fly   541 GVYVQFPNSGRRYSWRKVTTTVNNIIVGKLWVDQHGEMEIRGSQAAEGHKCILNFIPYSYFSRDV 605
            .|.|..|..|..|.|.||||.::||:.|:.|::.:||:.||.::.... .|.:.||..||::...
 Frog   680 TVNVTLPKYGDCYIWNKVTTCIHNILSGRRWIEHYGEITIRNTKNCVS-MCKMTFIKGSYWNSSA 743

  Fly   606 QRSVKGVVMNKDNEVKWVVRGTWDMKIEI--APVLKTSGSVSSPTYTTGEFKLAWRRRPAPPDSD 668
             ..|.||||:::.:|...:.|.|...:..  ||..                |..||....|.:.:
 Frog   744 -NEVHGVVMDQEGKVVHRLFGKWHEGLYCGDAPAA----------------KCIWRPGSMPTNYE 791

  Fly   669 KFYNFTTLACQLNEEE----EGVAPTDSRLRPDQRLMEQGDWDESNKEKLRLEEKQRTERRRREN 729
            .:|.||..|.:|||.:    :.:..||:|.||||||:|:|:.:.:..||.|:||.||:.|:..|.
 Frog   792 LYYGFTRFAIELNELDPVLKDFLPLTDARFRPDQRLLEEGNVEAAAMEKQRIEELQRSRRKCMEE 856

  Fly   730 EAEEAAAEGRPYPAYEPMWFKREKEEGSEEYVHVFKNTYWEAKAAQNF 777
            :..|          |...:|::..:...:| :.:..:||||.:....|
 Frog   857 DHVE----------YTTKYFRKVIDFHQKE-MWISNDTYWELRKDPGF 893

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Osbp	NP_477271.1	PH	15..107	CDD:278594	31/134 (23%)
		PH_OSBP_ORP4	17..113	CDD:270101	30/138 (22%)
		Oxysterol_BP	399..764	CDD:279564	150/371 (40%)
osbpl6	XP_002935731.2	PH_ORP3_ORP6_ORP7	35..157	CDD:270104	32/121 (26%)
		Oxysterol_BP	538..886	CDD:395990	152/377 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542090at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X203
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010