DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Osbp and CG9205

DIOPT Version :9

Sequence 1:	NP_477271.1	Gene:	Osbp / 42985	FlyBaseID:	FBgn0020626	Length:	784	Species:	Drosophila melanogaster
Sequence 2:	NP_612075.1	Gene:	CG9205 / 38113	FlyBaseID:	FBgn0035181	Length:	224	Species:	Drosophila melanogaster

Alignment Length:	176	Identity:	46/176 - (26%)
Similarity:	76/176 - (43%)	Gaps:	26/176 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LAEKGLPEMKGWLLKWTNYIKGYQRRWFVL--SKGVLSYYRNQSE------------INHTCRGT 59
            :.|....::.|.|.|:||.:||:|.|||.:  ..|.||||...|.            :....||.
  Fly     9 IRESAKLKLCGQLSKYTNVMKGWQYRWFTVDAKTGSLSYYLCDSSTVGDDIAPSPHVLASAPRGQ 73

  Fly    60 ISLHGALIH--TVDSCTFVISNGGTQTFHIKAGTEVERQSWVTALELAKAKAIRAIECEEEEETE 122
            :.|.||:::  ..||.||.|:.....|..::|.....||.||..|.......::|::......
  Fly    74 VQLAGAVVYPSDEDSRTFAIACASGDTVKLRANDARARQEWVDGLRAVVESHMKAMDISNSSP-- 136

  Fly   123 TAHVVPSQEISSVVRDLTDRLESMRTCYDLITKHGAALQRALNDLE 168
                :|.:|:.:.    :|.:.|.|....|..:..|:|.||:..::
  Fly   137 ----LPPRELLAA----SDAMVSARQALFLTEQCNASLARAIESID 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Osbp	NP_477271.1	PH	15..107	CDD:278594	34/107 (32%)
		PH_OSBP_ORP4	17..113	CDD:270101	34/111 (31%)
		Oxysterol_BP	399..764	CDD:279564
CG9205	NP_612075.1	PH	15..123	CDD:278594	34/107 (32%)
CG9205	NP_612075.1	PH_ORP10_ORP11	17..135	CDD:270106	35/117 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460430
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840