Protein Alignment Osbp and CG1513

DIOPT Version :9

• Sequence 1: NP_477271.1
• Gene: Osbp / 42985
• FlyBaseID: FBgn0020626
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_610534.3
• Gene: CG1513 / 36028
• FlyBaseID: FBgn0033463
• Length: 784
• Species: Drosophila melanogaster
• Alignment Length: 929
• Identity: 202/929 - (21%)
• Similarity: 333/929 - (35%)
• Gaps: 300/929 - (32%)

  Fly     1 MTDAAGNALAEKGLPE--------MKGWLLKWTNYIKGYQRRWFVLSK--GVLSYYRNQSE-INH 54
            |....|:| ...|.|:        ::|.|.||||.:||:|.|:|||.:  |:||||.::.: |..
  Fly     1 MASTTGSA-PSLGPPQSGSGGSGTLEGTLSKWTNVMKGWQYRFFVLDENAGLLSYYTSKDKMIKG 64

  Fly    55 TCRGTISLHGALIHTVD--SCTFVISNGGTQTFHIKAGTEVERQSWVTALELAKAKAIRAIECEE 117
            ..||.:.|..|||...|  ..||.|: ...:|||.:|....||:.||..|
  Fly    65 VRRGCVRLKDALIGIDDQEDNTFTIT-VDHKTFHFQARHNEEREQWVRRL--------------- 113

  Fly   118 EEETETAHVVPSQEISSVVRDLTDRLESMRTCYDL---ITKHGAAL---QRALNDLE-----TNE 171
             |:|...|...|            ||...::.:.:   .||.|...   .|..|.||     .:|
  Fly   114 -EDTIRRHANRS------------RLWDSQSAFYIAGGYTKEGGGSGTGGRRPNHLELVARRVSE 165

  Fly   172 EES----LGSRTKIVNERATLFRITSNAMINAGNDYLHTAEAQGHKWSKMLHHEREQRQRLEEII 232
            .::    :..:|.::::|  :..:|..|..:........|.|       ||.|.:.....| :|.
  Fly   166 ADAYLQLMIEQTNLLDKR--IAELTDPAEQSKCKALQDNANA-------MLDHIKHSIVSL-QIA 220

  Fly   233 EQMAKQ--------------------------------------QSQMEQAAVLVRQNKPVSSTS 259
            :.||..                                      :.|:.....|| .::..|:|.
  Fly   221 KNMAHPINGIYNGPPATASTSSSTSGVAMGSCNNVQAGGLKVPLEGQVIGKGELV-DDEEDSATE 284

  Fly   260 GAGTA--GSLV------TSDEEMEFFDAEEHGYSGSGRSPESSDCERGTFILKMHKRRSSSED-- 314
            .|.||  |.:|      :|:.|.:|:||.:..::..|.||  ..|....|..........:.|
  Fly   285 NATTAPLGLIVPATSYSSSEGEEDFYDAYDDPFTSIGSSP--IGCATRGFAETTSPTHEKAPDGF 347

  Fly   315 --------------QVEGHLEGSSSESDEQKRTVQTVQQVCLVSAPRVASGGQGDDDDDVDKALP 365
                          |....::.|.:::|...:|.:|.     ||: |.||...|.|
  Fly   348 ANAEPVAVGDSVAPQTLPEIDESVADADTSIKTARTA-----VSS-RSASYDNGID--------- 397

  Fly   366 AKESTDSIYGRNWNPDLIKKRRDRVPDKPNHPISLWGIMKNC-IGKDLSKIPMPINFNEPLSMLQ 429
                .|::|......||..:.         |...:..::... ||.||:|:.:|....|..|:|:
  Fly   398 ----YDALYEEEEETDLSMEA---------HGSMITHLLSQVKIGMDLTKVVLPTFILERRSLLE 449

  Fly   430 RLVEDYEYTEILDYAATCQDECEQLAYIAAFTVSAY--ATTTNRTGKPFNPLLGETYECD----- 487
            ...:.:.:.::....:...|..:::..:..:.:|||  ...:....||:||:|||.::|.
  Fly   450 MYADYFAHPDLFIKISDLDDPRDRIVQVCRWYMSAYHAGRKSAVAKKPYNPILGEVFQCHWDIPG 514

  Fly   488 --------RMDDYGWRC-------LAEQVSHHPPVAALHCESKN---------WTCWQEFSMTSK 528
                    |.....| |       ||||||||||::|.:.|..|         ||       .||
  Fly   515 ISQDAQEVRDGPVPW-CRRDQLTFLAEQVSHHPPISAFYAEHYNKKITFAAHVWT-------KSK 571

  Fly   529 FRGKYVQINPLG-GV----------YVQFPNSGRRYSWRKVTTTVNNIIVGKLWVDQHGEMEIRG 582
            |.|..:.::.:| ||          .|.|||.   |. |.:.|..        |::..|.:||
  Fly   572 FLGLSIGVHNIGEGVVTLVDRSEEYIVTFPNG---YG-RSILTVP--------WIELGGSVEI-- 622

  Fly   583 SQAAEGHKCILNFIPYSYFSRDVQRSVKGVVMNKDNEVKWVVRGTWDMKIEIAPVLKTSGSVSSP 647
                   ||     |.|.:..:|:...|.....|.|.|...|....:.|    |.:..:|..|
  Fly   623 -------KC-----PQSGYYANVEFLTKPFYGGKRNRVSAEVYAPSEKK----PFVSITGEWS-- 669

  Fly   648 TYTTGEFKLAWRRRPAPPDSDKFYNFTTLACQLNEEEEGVAPTDSRLRPDQRLMEQGD------W 706
                |..:..|.        ||  |.|.:...:|.    :.....::||   ::||.:      |
  Fly   670 ----GLMEAKWH--------DK--NKTEVFVDVNR----IPIFKKQVRP---IVEQDEYESRRVW 713

  Fly   707 DE------------SNKEKLRLEEKQRTERRRRENEAEEAAAEGRPYPAYEPMWFKREKEEGSEE 759
            .|            :...|..:|::||.:.:.|:.              |:..|..:..:...:.
  Fly   714 KEVTAGLKFNDIERATTAKFVVEQQQRDQAKVRKE--------------YDLAWEHKHFKPVGDN 764

  Fly   760 YVH---VFKNTYWEAKAAQ 775
            :::   :.:..|.:.|.|:
  Fly   765 WIYAKPLSQRMYLQEKEAK 783

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Osbp	NP_477271.1	PH	15..107	CDD:278594	39/104 (38%)
		PH_OSBP_ORP4	17..113	CDD:270101	38/100 (38%)
		Oxysterol_BP	399..764	CDD:279564	91/428 (21%)
CG1513	NP_610534.3	PH_ORP9	24..125	CDD:241444	42/129 (33%)
		PH	25..118	CDD:278594	40/109 (37%)
		Oxysterol_BP	421..767	CDD:279564	91/420 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460429
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10972
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940