Protein Alignment Osbp and Osbpl7

DIOPT Version :9

• Sequence 1: NP_477271.1
• Gene: Osbp / 42985
• FlyBaseID: FBgn0020626
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_006247361.1
• Gene: Osbpl7 / 303497
• RGDID: 1309141
• Length: 837
• Species: Rattus norvegicus
• Alignment Length: 886
• Identity: 257/886 - (29%)
• Similarity: 398/886 - (44%)
• Gaps: 209/886 - (23%)

  Fly     6 GNALAEKGLPE-MKGWLL---KWTNYIKGYQRRWFVLSKGVLSYYRNQSEINHTCRGTISLHGAL 66
            |...||..:|| .:|.||   ||.  :||:.:|:|||..|||.|...:.:|.   :|.:  ||
  Rat    38 GRLGAEDIMPERQEGHLLKKRKWP--LKGWHKRYFVLEDGVLHYATTRQDIT---KGKV--HG-- 93

  Fly    67 IHTVDSCTFVIS-NGGTQ---------TFHIKAGTEVERQSWVTAL---ELAKAKAIRAIECEEE 118
              ::|....|:| |...|         .:|:|..::...||||:.|   .||:...:......:.
  Rat    94 --SIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQDLFQSWVSQLRAHRLAQRSDLPNATHRKA 156

  Fly   119 EETET---------AHVVPSQEISSVVRDLTDRLE----SMRTCYDLITKHGAALQRALNDLE-- 168
            ..|:|         ..|.|.:::||.:|| :|.|:    ::..|...:.:    |.|.|..||
  Rat   157 PGTQTLTAGSASALPGVGPREKVSSWLRD-SDGLDRCSHALSECQGKLQE----LHRLLQSLESL 216

  Fly   169 ----------------TNEEESLGSRT-----------------------KIVN-ERATLFRITS 193
                            |.|....|.||                       .:.| .|....|.||
  Rat   217 HRIPSAPVIPTHQASVTTERPKKGKRTSRMWCTQGFAKDDTIGRVGRLHGSVPNLSRYLESRDTS 281

  Fly   194 NAMINAGNDYLH-------TAEAQGHKWSKMLHHEREQRQRLEEIIEQMAKQQSQMEQAAVLVRQ 251
            ........||.|       .|:...:..|.:|.....:|.||.::     .|.|::.:.||
  Rat   282 GPRGLPPPDYAHLQRSFWALAQKVHNSLSSVLVALTTERDRLRDL-----HQGSELSRMAV---- 337

  Fly   252 NKPVSSTSGAGTAGSL-VTSDEEMEFFDA----EEHGYSGSGR--SPESSDCERGTFILKMHKRR 309
               ..:..|.....|| ::||...:.|.:    |:......||  :|:.|.    :.:|.:....
  Rat   338 ---SEAPDGQRRLHSLSISSDTTADSFSSLNPEEQEALYRKGRELTPQLSQ----SSVLSLADSH 395

  Fly   310 SSSEDQVEGHLEGSSSESDEQKRTVQTVQQVCLVSAPRVASGGQGDDDDDVDKALPAKESTDSIY 374
            :...|..|..|..||||::..:.     ::.|                        |.|.|.|:
  Rat   396 TEFFDACEVLLSASSSENEGSEE-----EESC------------------------ASEITTSL- 430

  Fly   375 GRNWNPDLIKKR-RDRVP---------------------DKPNHPISLWGIMKNCIGKDLSKIPM 417
                :.:::..| .||.|                     ..|...:|||.|::|.|||||||:.|
  Rat   431 ----SEEVLDIRGADRYPKGACVPGIAVGPPRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSM 491

  Fly   418 PINFNEPLSMLQRLVEDYEYTEILDYAATCQDECEQLAYIAAFTVSAYATTTNRTG-KPFNPLLG 481
            |:..||||:.||||.|:.||:.:||.|:...|.||::.|||||.||||::|.:|.| |||||:||
  Rat   492 PVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLG 556

  Fly   482 ETYECDRMDDYGWRCLAEQVSHHPPVAALHCESKNWTCWQEFSMTSKFRGKYVQINPLGGVYVQF 546
            |||||:| .|.|:|.::||||||||::|.|.||:|:..||:....:||.||.::|.|:|.|.|..
  Rat   557 ETYECER-PDRGFRFISEQVSHHPPISACHAESENFIFWQDMKWKNKFWGKSLEIVPVGTVNVSL 620

  Fly   547 PNSGRRYSWRKVTTTVNNIIVGKLWVDQHGEMEIRGSQAAEGHKCILNFIPYSYFSRDVQRSVKG 611
            |..|..:.|.|||:.::||:.|:.|::.:||:.||.:|.:..| |.:.|....|:|.:: ..|:|
  Rat   621 PRFGDHFEWNKVTSCIHNILSGQRWIEHYGEVLIRNTQDSSCH-CKITFCKAKYWSSNI-HEVQG 683

  Fly   612 VVMNKDNEVKWVVRGTWDMKIEIAPVLKTSGSVSSPTYTTGEFKLAWRRRPAPPDSDKFYNFTTL 676
            .|:::...|...:.|.|...:...|   ..|.           :..|:....|||.::.:.||..
  Rat   684 AVLSRSGRVLHRLFGKWHEGLYRGP---PPGG-----------QCIWKPNSMPPDHERNFGFTQF 734

  Fly   677 ACQLNE---EEEGVAP-TDSRLRPDQRLMEQGDWDESNKEKLRLEEKQRTERR-RRENEAEEAAA 736
            |.:|||   |.:...| ||:|||||||.:|:|:...:..:|.|:|:.||..|| ..||..
  Rat   735 ALELNELTAELKRTLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRRVMEENNI----- 794

  Fly   737 EGRPYPAYEPMWFKREKEEGSEEYVHVFKNTYWEAKAAQNF 777
                  .::..:|:|:.:...:|: .|..:|||..:|...:
  Rat   795 ------VHQARFFRRQTDSSGKEW-WVTNHTYWRLRAEPGY 828

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Osbp	NP_477271.1	PH	15..107	CDD:278594	35/108 (32%)
		PH_OSBP_ORP4	17..113	CDD:270101	33/111 (30%)
		Oxysterol_BP	399..764	CDD:279564	146/370 (39%)
Osbpl7	XP_006247361.1	PH_ORP3_ORP6_ORP7	27..149	CDD:270104	38/121 (31%)
		PH	51..139	CDD:278594	31/98 (32%)
		Oxysterol_BP	473..814	CDD:279564	146/369 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1737
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542090at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X203
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820