Protein Alignment Osbp and obr-2

DIOPT Version :9

• Sequence 1: NP_477271.1
• Gene: Osbp / 42985
• FlyBaseID: FBgn0020626
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_506695.2
• Gene: obr-2 / 180003
• WormBaseID: WBGene00008832
• Length: 436
• Species: Caenorhabditis elegans
• Alignment Length: 426
• Identity: 134/426 - (31%)
• Similarity: 205/426 - (48%)
• Gaps: 56/426 - (13%)

  Fly   382 LIKKRRDRVPDKPNHP--ISLWGIMKNCIGKDLSKIPMPINFNEPLSMLQRLVEDYEYTEILDYA 444
            |.|.:|.|:|.....|  :|:|.|::..:|||.|:..:|:..|||||.||||.|:.:|..:|:.|
 Worm    25 LHKGQRTRLPATYIAPEDVSIWDIIRPNLGKDFSRFTVPVFMNEPLSFLQRLSENVQYNYLLEKA 89

  Fly   445 ATCQDECEQLAYIAAFTVSAYATTTNRTGKPFNPLLGETYECDRMDDYGWRCLAEQVSHHPPVAA 509
            |.|.|:.|::.|:|||.::..:....|..|||||||.||:|.:|   .|.|.||||||||||::|
 Worm    90 AKCSDDMERIEYVAAFALATVSANHKRLSKPFNPLLLETFELER---NGVRFLAEQVSHHPPISA 151

  Fly   510 LHCESKNWTCWQEFSMTSKFRGKYVQINPLGGVYVQFPNSGRRYSWRKVTTTVNNIIVGKLWVDQ 574
            ::.||..:|.......|..|....:..||...:.:.|..:|..|||......:.|:|:||::::.
 Worm   152 VYAESDEFTVEGTVEPTLGFWMTKLLANPHAHLKLTFKKTGETYSWSAPKCAIYNVIMGKMYMNF 216

  Fly   575 HGEMEIRGSQAAEGHKCILNFIPYSYFSR---DVQRSVKGVVMNKDNEVKWVVRGTW-------- 628
            ...|:|..|..   :..:.:|....|::.   ||.  |:|.:....|::| .:.|.|
 Worm   217 TSHMKIESSGT---YDAVFSFDNKGYYNHKGGDVH--VEGHIFEGKNKIK-ALYGNWTLFLASCD 275

  Fly   629 --DMKIEIAPVLK----TSGSVSSPTYTTGEFKLAWRRRPAPPDSDKFYNFTTLACQLNEEEEG- 686
              |.|......|:    |...........|. |:.|.....|...|..::||.....|||...|
 Worm   276 NEDFKHHRKEYLRMFNETVSEKDQGPVVPGS-KILWVSNQIPKLFDDQFHFTNFTLSLNEMYPGM 339

  Fly   687 ---VAPTDSRLRPDQRLMEQGDWDESNKEKLRLEEKQRTERRRRENEAEEAAAEGRPYPAYEPMW 748
               |||||||.|.|.:.:|.|..||:.:.|.:.||:||..|..:..:.              |||
 Worm   340 SDTVAPTDSRRRKDMKALEDGKNDEAEEFKHKYEEEQRERRTTKTGDV--------------PMW 390

  Fly   749 FKREKEEGSEEYVHVFKNTYWEAKAAQNFEGCPDIY 784
            |.: .:||...|    |..||:    :::..|.:::
 Worm   391 FAK-NDEGHWAY----KGGYWD----RDYSNCLELF 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Osbp	NP_477271.1	PH	15..107	CDD:278594
		PH_OSBP_ORP4	17..113	CDD:270101
		Oxysterol_BP	399..764	CDD:279564	124/385 (32%)
obr-2	NP_506695.2	Oxysterol_BP	44..401	CDD:279564	123/381 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3013
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940