Protein Alignment Osbp and osbpl10

DIOPT Version :10

• Sequence 1: NP_477271.1
• Gene: Osbp / 42985
• FlyBaseID: FBgn0020626
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_002941862.1
• Gene: osbpl10 / 100496082
• XenbaseID: XB-GENE-995970
• Length: 768
• Species: Xenopus tropicalis
• Alignment Length: 833
• Identity: 193/833 - (23%)
• Similarity: 328/833 - (39%)
• Gaps: 233/833 - (27%)

  Fly     6 GNALAEKGLPEMK----GWLLKWTNYIKGYQRRWFVL--SKGVLSYYRNQSEINHTCRGTISLHG 64
            |.|.|.||..|.|    |.|.|:||.|:|:|.|:|:|  ..|:|.||..::..|...||::||.|
 Frog    76 GAAQASKGGREHKQVIEGVLSKYTNLIQGWQNRYFILDFDSGILQYYVTEASKNQKPRGSLSLSG 140

  Fly    65 ALIHTVDSCTFVI----SNGGTQTFHIKAGTEVERQSWVTALELAKAKAIRAIECEEEEETETAH 125
            ::|...:....||    :||  :.:.::|....|||.|:|.|: |.||.        ..|:::|
 Frog   141 SVISLSEEAPNVIIVYSTNG--EMYKLRAADAKERQFWMTQLQ-ACAKF--------HSESKSA- 193

  Fly   126 VVPSQEISSVVRDLTDRLESMRTCYDLITKHGAALQRALNDLETNEEESLGSRTKIVNERATLFR 190
                         ::.|..|    |.|: .||           |:...|..|:.::.:...::..
 Frog   194 -------------VSQRARS----YSLL-PHG-----------TSNSPSPASQRQMTHSGPSIVT 229

  Fly   191 ITSNAMINAGNDYLHTAEAQGHKWSKMLHHEREQRQRLEEIIEQMAKQQSQMEQAAVLVRQNKPV 255
            :|.           |.:.|...: ||  :....|...::|::.|:..||..:..|         :
 Frog   230 VTH-----------HKSPAAARR-SK--NQNPAQLHEVKEVMAQVEGQQKNLVHA---------I 271

  Fly   256 SSTSGAGTAGSLVTSDEEMEFFDA----------------EEHGY-SGSGRSPESSDCERGTFIL 303
            .|.||:|...:|   |:::....|                ::..| ||......|:|.     ||
 Frog   272 ESLSGSGPLSAL---DQDLLLLKATSAATLSCLGECLHLLQQSVYQSGQNNKNISTDS-----IL 328

  Fly   304 KMHKRRS-SSEDQVEGHLEGSSSESDEQKRT---VQTVQQVCLV------SAPRVASGGQGDDDD 358
            ..|..:| |:|:...|||  ||..|.:...|   :.::.|...|      :.|..|.....|.:|
 Frog   329 SWHGPKSHSTENLKNGHL--SSLPSSDTNLTWPIIPSMPQDYKVLERDTETGPPEAEEELTDTED 391

  Fly   359 DVDKALPAKESTDSIYGRNWNPDLIKKRRDRVPDKPNHPISLWGIMKNCIGKDLSKIPMPINFNE 423
            :.::.|...:...|:.                       :.|...:|  :|.||:|:.:|....|
 Frog   392 NEEEDLGVMDDQRSVI-----------------------LHLISQLK--LGMDLTKVVLPTFILE 431

  Fly   424 PLSMLQRLVEDYEYTEI-LDYAATCQDECEQLAYIAAFTVSAYATTTNRTG----KPFNPLLGET 483
            ..|:|:.......:.:: |..||....| |::.....:.::|:  ...|.|    ||:||:||||
 Frog   432 KRSLLEMYANFMAHPDLFLSIAAGATPE-ERIICFVEYYLTAF--HEGRKGAVAKKPYNPVLGET 493

  Fly   484 YEC--------------------------DRMDDYGWRCLAEQVSHHPPVAALHCESKN------ 516
            :.|                          ...:.|..|.:||||||||||:..:||.|.
 Frog   494 FHCSWDVPKENVKSFRTQSASKETVPPPSSSGEAYKLRFVAEQVSHHPPVSCFYCECKEKKMCVN 558

  Fly   517 ---WTCWQEFSMTSKFRGKYVQINPLGGVYVQFPNSGRRYSWRKVTTTVNNIIVGKLWVDQHGEM 578
               ||       .|||.|..|.::.:|...::....|..|.:...:....:|:... ||:..|::
 Frog   559 AHVWT-------KSKFLGMSVGVSMVGEGILRLMEHGEEYVFTLPSAYARSILTVP-WVELGGKV 615

  Fly   579 EIRGSQAAEGHKCILNFIPYSYFSRDVQRSVKGVVMNKDNEVKWVVRGTWDMKIEIAPVLKTSGS 643
            .|  |.|..|:...:.|....::...|.|....|..|..|.:....:|.|:..:|.
 Frog   616 NI--SCAKTGYVATVIFHTKPFYGGKVHRVTAEVKHNPTNTMVCKAQGEWNGTLEF--------- 669

  Fly   644 VSSPTYTTGEFKLAWRRRPAPPDSDKFYNFTTLACQLNEEEEGVAPTDSRLRPDQR--------L 700
                ||:|||.||.        |:.|..|.          ::.:.|.:.:.:.:.|        .
 Frog   670 ----TYSTGETKLI--------DTTKLLNI----------KKKIRPLEKQGQCESRRVWENVTNA 712

  Fly   701 MEQGDWDESNKEKLRLEEKQRTERRRREN-----EAEEAAAEGRPYPAYEPMW 748
            ::.|:.:.::::|.:|||:||.|.|:|.:     :.:....||..:....|:|
 Frog   713 LKSGNIEAASEQKHQLEERQRAESRQRASLNTTWKPKYFIKEGEGWAYVNPIW 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Osbp	NP_477271.1	PH_OSBP_ORP4	17..113	CDD:270101	37/105 (35%)
		Oxysterol_BP	399..773	CDD:460126	95/403 (24%)
osbpl10	XP_002941862.1	PH_ORP10_ORP11	91..197	CDD:270106	38/130 (29%)
		Oxysterol_BP	409..766	CDD:460126	95/403 (24%)