DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11771 and AT5G65620

DIOPT Version :9

Sequence 1:	NP_651314.1	Gene:	CG11771 / 42984	FlyBaseID:	FBgn0039252	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	NP_001332654.1	Gene:	AT5G65620 / 836688	AraportID:	AT5G65620	Length:	805	Species:	Arabidopsis thaliana

Alignment Length:	809	Identity:	218/809 - (26%)
Similarity:	372/809 - (45%)	Gaps:	134/809 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LNLLRR--------------RPTS-----------------VPLIRAALSAPLHSTENRP----- 30
            ||||||              ||::                 :|..|:..|..|.|:..||
plant    26 LNLLRRSPKPKYFSSSSCHFRPSTFRKSYPCPIWSSSFSFCLPPPRSTTSTSLSSSSFRPFSSPP 90

  Fly    31 ----GYIVLVPEIGEEGPLGEGVLKPD-GLPAFSDITIEMCLGAIGQQASAVENSVKA----LES 86
                .....|..:..:..|....|..| ..|.|..:           .||.|...::|    ||:
plant    91 SMSSAAAAAVESVVSDETLSSNPLLQDFDFPPFDSV-----------DASHVRPGIRALLQHLEA 144

  Fly    87 DLHSGKQLNAA------SIFRELDTVTGPLETTWGVAKALYLGNST---------LIPTKSYMNI 136
            :|   ::|..:      .:...|:.:...|...||:...|.....|         :.|.|    :
plant   145 EL---EELEKSVEPTWPKLVEPLEKIVDRLTVVWGMINHLKAVKDTPELRAAIEDVQPEK----V 202

  Fly   137 HERARNARAAKFCNQTVYKALKDASSDSGPDE--QRMRQKFLLEGKLNGLTLDKDKQDGLKELLT 199
            ..:.|..::....|  .:||::::...|...|  ||:.:..:.|..|.|:.||.:|::...::..
plant   203 KFQLRLGQSKPIYN--AFKAIRESPDWSSLSEARQRLVEAQIKEAVLIGIALDDEKREEFNKIEQ 265

  Fly   200 HLGRERANFKNKVNMAVHSFGQIITDFNLVRDFPPSLL-------------EATARDPGQPMTGP 251
            .|.:....|...|..|...|.::|||...:...|||.|             .|||.:      ||
plant   266 ELEKLSHKFSENVLDATKKFEKLITDKKEIEGLPPSALGLFAQAAVSKGHENATAEN------GP 324

  Fly   252 WKITLQPQVVDGFLKHCPERMQRWNVWRASVLKASSQQEKSLENSTHIEKIRGLRKRQANLLGYE 316
            |.|||........::|...|..|..|:||.:.:|||   ..|:|:..|::|..||..:|.||||.
plant   325 WIITLDAPSYLPVMQHAKNRALREEVYRAYLSRASS---GDLDNTAIIDQILKLRLEKAKLLGYN 386

  Fly   317 SFADMSMQTKMVGSVDNLKQIFAKLLKFAGPAQSVELEKLQGFAQDSGC--EYKLEAYDVAYWRR 379
            ::|::||..|| .:|:...::..||...:..|...::|.|:.||::.|.  ...:..:|..:|..
plant   387 NYAEVSMAMKM-ATVEKAAELLEKLRSASWDAAVQDMEDLKSFAKNQGAAESDSMTHWDTTFWSE 450

  Fly   380 KQLAAEHGLQDQKLREFFPLPRVLSGLFALSEKLFGIKIVEQPN---AEVWHPAVKFYDVFDADS 441
            :...:::.:.:::||.:|.||:|:.|||:|::.||||.|  :|.   |.||:..|:||.|.|
plant   451 RLRESKYDINEEELRPYFSLPKVMDGLFSLAKTLFGIDI--EPADGLAPVWNNDVRFYRVKD--- 510

  Fly   442 VNSSTPVGGFYVDCYSKEHKFGRNNGWMVGIRNSNK------SAGLTPLCALIFNFSEPQSPDAK 500
             :|..|:..||.|.||:..: .|...||..:.:.::      |:...|:..::.|.:.|...  |
plant   511 -SSGNPIAYFYFDPYSRPSE-KRGGAWMDEVVSRSRVMAQKGSSVRLPVAHMVCNQTPPVGD--K 571

  Fly   501 PPLLGYDDLQMLFKTFGSGLQHLLTQAGYSDLAGLSNIEWDASQVSGHVMSNFLDDPTVIRSLSG 565
            |.|:.:.:::.:|..||..|||:||:.....:||:.||||||.::....|.|:......:.|::.
plant   572 PSLMTFREVETVFHEFGHALQHMLTKQDEGLVAGIRNIEWDAVELPSQFMENWCYHRDTLMSIAK 636

  Fly   566 HFSSGEPLEAELSQKMRLLKTQLAGYNLCQDLYLADLDVELHRS------NAFWLEVVRKLWPVY 624
            |:.:||.|..|:.:|:...:|..||....:.|..|.:|:|||..      .:.: :|.:::....
plant   637 HYETGETLPEEVYKKLLAARTFRAGSFSLRQLKFASVDLELHTKYVPGGPESIY-DVDQRVSVKT 700

  Fly   625 QCMPLDKKDAHPCSLTDIFAGDWAAAQFSHLYSRLIAADISSSFAEQRSEENYAV--VGRRYKQT 687
            |.:|...:|...||.:.||||.:||..:|:.::.:::||..|:|.:...::..||  .|:|::.|
plant   701 QVIPPLPEDRFLCSFSHIFAGGYAAGYYSYKWAEVLSADAFSAFEDAGLDDIKAVKETGQRFRNT 765

  Fly   688 FLSCGGSVPTAEVFRRFQGRDPSAEALLK 716
            .|:.||.....:||..|:||:||.|.||:
plant   766 ILALGGGKAPLKVFVEFRGREPSPEPLLR 794

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11771	NP_651314.1	PRK10911	49..720	CDD:182832	201/722 (28%)
CG11771	NP_651314.1	Peptidase_M3	264..720	CDD:279740	146/472 (31%)
AT5G65620	NP_001332654.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	223	1.000	Domainoid score	I701
eggNOG	1	0.900	-	-		E1_COG0339
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H77003
Inparanoid	1	1.050	258	1.000	Inparanoid score	I989
OMA	1	1.010	-	-		QHG56544
OrthoDB	1	1.010	-	-		D642479at2759
OrthoFinder	1	1.000	-	-		FOG0001673
OrthoInspector	1	1.000	-	-		otm2578
orthoMCL	1	0.900	-	-		OOG6_100561
Panther	1	1.100	-	-	LDO	PTHR11804
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1228
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840