Protein Alignment CG11771 and Nln

DIOPT Version :9

• Sequence 1: NP_651314.1
• Gene: CG11771 / 42984
• FlyBaseID: FBgn0039252
• Length: 730
• Species: Drosophila melanogaster
• Sequence 2: XP_011243001.1
• Gene: Nln / 75805
• MGIID: 1923055
• Length: 746
• Species: Mus musculus
• Alignment Length: 761
• Identity: 171/761 - (22%)
• Similarity: 300/761 - (39%)
• Gaps: 205/761 - (26%)

  Fly    60 DITIEMCLGAIG--QQASAVENSVKALESDLHSGKQLNAASIFRELDTVTGPLETTWGVAKALYL 122
            |:|.|.||..:.  :....||.::......:.|.:::.|||  .|.|......:....:.:.::
Mouse    82 DVTYENCLQVLADIEVKYIVERTMLDFPQHVSSDREVRAAS--TEADKRLSRFDIEMSMREDVF- 143

  Fly   123 GNSTLIPTKSYMNIHERARNARAAKFCNQTVYKALKDASSDSGPDEQRMRQKFLLEGKLNGLTLD 187
                             .|.....:.|:....|          |:.:|..:|.:..||.|||.|.
Mouse   144 -----------------QRIVHLQETCDLEKIK----------PEARRYLEKSIKMGKRNGLHLP 181

  Fly   188 KDKQDGLKELLTHLGRERANFKNKVNMAVHSFGQIITDFN-------------------LVRDFP 233
            :                  :.||::........::..|||                   |..||.
Mouse   182 E------------------HVKNEIKSMKKRMSELCIDFNKNLNEDDTSLVFSKAELGALPDDFI 228

  Fly   234 PSLLEATARDPGQPMTGPWKITLQPQVVDGFLKHC--PERMQRWNV------------------- 277
            .| ||.|..|       .:|:||:.......:|.|  ||..::..:
Mouse   229 DS-LEKTDED-------KYKVTLKYPHYFPVMKKCCVPETRRKMEMAFHTRCKEVRTLTALADDP 285

  Fly   278 -------W-RASVLKASSQQE-------KSLENSTHIEKIRGLRKRQANLLGYESFADMSMQTKM 327
                   | .|::.|:|::..       |..||:..::::..||.:.|.||||.:.||..::...
Mouse   286 DLVPSTTWCPAAISKSSTRGSDDPFGPLKLQENTIILQQLLPLRAQVAKLLGYNTHADFVLELNT 350

  Fly   328 VGS-------VDNLKQIFAKLLKFAGPAQS---VELEKLQ----GFAQDSGCEYKLEAYDVAYWR 378
            ..|       :|:|.|    .||..|.|:.   :.|:|.:    |||.|.    |:.|:|:.|:.
Mouse   351 AKSTSHVATFLDDLSQ----KLKPLGEAEREFILSLKKKECEERGFAYDG----KINAWDLHYYM 407

  Fly   379 RKQLAAEHGLQDQKLREFFPLPRVLSGLFALSEKLFGIKIVEQPNAEVWHPAVKFYDVFDADSVN 443
            .:....::.:..:.|:|:||:..|..||.::.::|.|:...:..:|.||:.:|..|.|.|.   .
Mouse   408 TQTEELKYSVDQESLKEYFPIEVVTEGLLSIYQELLGLSFEQVADAHVWNKSVSLYTVKDK---A 469

  Fly   444 SSTPVGGFYVDCYSKEHKFGRNNGWMVGIRNSNKSAGLTPLC------------ALIFNFSEPQS 496
            :...:|.||:|.|.:|.|:           |.....||.|.|            ||:.|||:|.:
Mouse   470 TGEVLGQFYLDLYPREGKY-----------NHAACFGLQPGCLLPDGSRMMSVAALVVNFSQPIA 523

  Fly   497 PDAKPPLLGYDDLQMLFKTFGSGLQHLLTQAGYSDLAGLSNIEWDASQVSGHVMSNFLDDPTVIR 561
              .:|.||.:|:::..|..||..:..:..|..::..:| :|:|.|..:|...::.|::.|...:|
Mouse   524 --GRPSLLRHDEVRTYFHEFGHVMHQICAQTDFARFSG-TNVETDFVEVPSQMLENWVWDIDSLR 585

  Fly   562 SLSGHFSSGEPLEAELSQKM---RLLKTQLAGYNLCQDLYLADLDVELHRSNAFWLEVVRKLWPV 623
            .||.|:..|.|:..||.:|:   ||:.|   |....:.:.|:.:|..|| :||
Mouse   586 KLSKHYRDGHPITDELLEKLVASRLVNT---GLLTLRQIVLSKVDQSLH-TNA------------ 634

  Fly   624 YQCMPLDKKDAHPCSLTDI-----------------FAGDWAAAQFSHLYSRLIAADISSSFAEQ 671
                .||....:....|:|                 .||.:....:.:|:|.:.:.|:..|...:
Mouse   635 ----SLDAASEYAKYCTEILGVAATPGTNMPATFGHLAGGYDGQYYGYLWSEVFSMDMFHSCFRK 695

  Fly   672 RSEENYAVVGRRYKQTFLSCGGSVPTAEVFRRFQGRDPSAEALLKS 717
            ....| ..||.:|:...|..|||:...::.:.|..|:|:.:|.|.|
Mouse   696 EGIMN-PEVGMKYRNLILKPGGSLDGMDMLQNFLQREPNQKAFLMS 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11771	NP_651314.1	PRK10911	49..720	CDD:182832	171/761 (22%)
		Peptidase_M3	264..720	CDD:279740	130/536 (24%)
Nln	XP_011243001.1	M3A	58..741	CDD:341068	171/761 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832223
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D642479at2759
OrthoFinder	1	1.000	-	-		FOG0001673
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100561
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2240
SonicParanoid	1	1.000	-	-		X1228
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.640