Protein Alignment CG11771 and MIPEP

DIOPT Version :9

• Sequence 1: NP_651314.1
• Gene: CG11771 / 42984
• FlyBaseID: FBgn0039252
• Length: 730
• Species: Drosophila melanogaster
• Sequence 2: NP_005923.3
• Gene: MIPEP / 4285
• HGNCID: 7104
• Length: 713
• Species: Homo sapiens
• Alignment Length: 620
• Identity: 131/620 - (21%)
• Similarity: 243/620 - (39%)
• Gaps: 115/620 - (18%)

  Fly   150 NQTVYKALKDASSDS------GPDEQRMRQKFLLEGKLNGLTLDKDKQDGLKEL------LTHLG 202
            |..:|::|:...:|.      .|:.:|:.:.|:.:.:::|:.|||:|:....:|      |:...
Human   155 NVDLYQSLQKLLADKKLVDSLDPETRRVAELFMFDFEISGIHLDKEKRKRAVDLNVKILDLSSTF 219

  Fly   203 RERANFKNKVN---MAVH------SFGQIITDFNLVRDFPPSLLEATARDPGQPMTGPWKITLQP 258
            ....||.||:.   :..|      |.|..|....|..:.|..|:...|          :||.|.|
Human   220 LMGTNFPNKIEKHLLPEHIRRNFTSAGDHIIIDGLHAESPDDLVREAA----------YKIFLYP 274

  Fly   259 QVVDGFLKHCPERMQRWNVWRASVLKASSQQEKSLENSTHIEKIRGLRKRQANLLGYESFADMSM 323
            ..  |.|| |                              :|::...|...|.|:||.:|:..::
Human   275 NA--GQLK-C------------------------------LEELLSSRDLLAKLVGYSTFSHRAL 306

  Fly   324 QTKMVGSVDNLKQIFAKLLKFAGPAQSVELEKLQGFAQDSGCEYKLE-------AYDVAYWRRKQ 381
            |..:..:.:.:.|...||      :..:....|:.|....|.:.||.       .:|..|:....
Human   307 QGTIAKNPETVMQFLEKL------SDKLSERTLKDFEMIRGMKMKLNPQNSEVMPWDPPYYSGVI 365

  Fly   382 LAAEHGLQDQKLREFFPLPRVLSGLFALSEKLFGIKI-VEQP-NAEVWHPAV-KFYDVFDADSVN 443
            .|..:.::......||.|...:.||..|..:|.||.: .||| ..|||...| |...|.:::.:
Human   366 RAERYNIEPSLYCPFFSLGACMEGLNILLNRLLGISLYAEQPAKGEVWSEDVRKLAVVHESEGL- 429

  Fly   444 SSTPVGGFYVDCYSKEHKFGRNNGWMV-GIRNSNKSAGLTPLCALIFNFSEPQSPDAKPPLLGYD 507
                :|..|.|.:.:..|..::..:.: |.|.........|:..|:.|.  |:|..:.|.||...
Human   430 ----LGYIYCDFFQRADKPHQDCHFTIRGGRLKEDGDYQLPVVVLMLNL--PRSSRSSPTLLTPS 488

  Fly   508 DLQMLFKTFGSGLQHLLTQAGYSDLAGLSNIEWDASQVSGHVMSNFLDDPTVIRSLSGHFSSGEP 572
            .::.||...|..:..:|.:..|..:.| :....|.::|...:|..|.:|..|:...:.|:.:|:|
Human   489 MMENLFHEMGHAMHSMLGRTRYQHVTG-TRCPTDFAEVPSILMEYFANDYRVVNQFARHYQTGQP 552

  Fly   573 LEAELSQKMRLLKTQLAGYNLCQDLYLADLDVELHRSNAF---WLEVVRKLWPVYQCMPLDKKDA 634
            |...:..::...|...|..::...::.|.||...|..:..   ..:::::....:..:|.....|
Human   553 LPKNMVSRLCESKKVCAAADMQLQVFYATLDQIYHGKHPLRNSTTDILKETQEKFYGLPYVPNTA 617

  Fly   635 HPCSLTDIFAGDWAAAQFSHLYSRLIAADI-SSSFAEQRSEENYAVVGRRYKQTFLSCGGSVPTA 698
            .....:.:..  :.|..:|:|.||.:|:.: ...|.:.....   ..|.||::..|:.||
Human   618 WQLRFSHLVG--YGARYYSYLMSRAVASMVWKECFLQDPFNR---AAGERYRREMLAHGG----- 672

  Fly   699 EVFRRFQGRDP--SAEALLK---SLDIFEPSQTTD 728
                   ||:|  ..|.:|:   |:|.|..:..:|
Human   673 -------GREPMLMVEGMLQKCPSVDDFVSALVSD 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11771	NP_651314.1	PRK10911	49..720	CDD:182832	128/610 (21%)
		Peptidase_M3	264..720	CDD:279740	97/475 (20%)
MIPEP	NP_005923.3	M3A_MIP	64..697	CDD:188996	130/615 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D642479at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820