DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trf4-2 and Mtpap

DIOPT Version :9

Sequence 1:	NP_001262941.1	Gene:	Trf4-2 / 42983	FlyBaseID:	FBgn0039251	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_080433.1	Gene:	Mtpap / 67440	MGIID:	1914690	Length:	585	Species:	Mus musculus

Alignment Length:	352	Identity:	72/352 - (20%)
Similarity:	142/352 - (40%)	Gaps:	92/352 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LHQEIEQFYNYIRSTPTEFCLRAGAVRRIEDVVLSIWPS-------ASVDLFGSFRTGLNLPDSD 85
            :.:::.......:.|.....||......|||:..:.:||       :||:.||.....|:: ..|
Mouse   189 IEEQLNTLLKAFQLTEENIRLRHLTCSLIEDIAAAYFPSCVIRPFGSSVNTFGKLGCDLDM-FLD 252

  Fly    86 ID----LVVYYKFWNPRLLHELQNELVSQGVTDPDTVTVLDK-----------------ASVPVV 129
            :|    |.|:....|..:..:::| :.|:.:.....::|:.:                 |..|:|
Mouse   253 LDETGKLDVHKNTGNFFMEFQVKN-VPSERIATQKILSVIGECLDNFGPGCVGVQKILNARCPLV 316

  Fly   130 KFTDLISRIRFDVTF-NSVASGVQAADLIKDFIRHFPELPKLVMVLKQFLSLHGFNEVYNSGGVS 193
            :|:...|..:.|:|. ||:|  :::::|:..:......:..||..::.:...|..........::
Mouse   317 RFSHQGSGFQCDLTANNSIA--LKSSELLYIYGSLDSRVRALVFSVRCWARAHSLTSSIPGAWIT 379

  Fly   194 SYALTLMVISFLQQHA---------------RSNRRLSEHSK------------------LALLL 225
            :::||:|||.|||:.:               ..:|.:.|.:.                  |.||:
Mouse   380 NFSLTVMVIFFLQRRSPPILPTLDSLKSIADAEDRCILEGNNCTFVQDVNKIQPSGNTETLELLI 444

  Fly   226 IQFLDYYGRKFDFFKYGISVLGQGGCVEKARLRSTLGENNW--QSVLCIEDPVTPTNDIGRSSYG 288
            .:|.:|:| .|.|.|..|:: .||            .|.|.  .|.|.|::|...:.:|.::
Mouse   445 KEFFEYFG-NFAFNKNSINI-RQG------------REQNKPDSSPLYIQNPFETSLNISKN--- 492

  Fly   289 VLGVMQGFGAAFVKLSKLVDSDSSKIV 315
               |.|.....||:|::    ||:.|:
Mouse   493 ---VSQSQLQKFVELAR----DSAWIL 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-2	NP_001262941.1	NT_PAP_TUTase	52..161	CDD:143392	29/137 (21%)
Trf4-2	NP_001262941.1	PAP_assoc	221..280	CDD:281779	18/60 (30%)
Mtpap	NP_080433.1	NT_PAP_TUTase	209..347	CDD:143392	31/141 (22%)
		PAP_assoc	441..486	CDD:281779	17/58 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	537..585
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810