DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Trf4-2 and tent4b

DIOPT Version :9

Sequence 1:	NP_001262941.1	Gene:	Trf4-2 / 42983	FlyBaseID:	FBgn0039251	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001313625.1	Gene:	tent4b / 568678	ZFINID:	ZDB-GENE-041021-2	Length:	653	Species:	Danio rerio

Alignment Length:	425	Identity:	162/425 - (38%)
Similarity:	230/425 - (54%)	Gaps:	70/425 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 PWQLPDVVYGNGIPALCLLHQEIEQFYNYIRSTPTEFCLRAGAVRRIEDVVLSIWPSASVDLFGS 74
            ||:..:  |.:||..   ||:||:.||.||...|.|..:|...|.||:.|:..:||:|.|.:|||
Zfish   155 PWKSRN--YSDGIVG---LHEEIKDFYEYISPRPEEEQMRHEVVARIQRVIKDLWPNAEVCVFGS 214

  Fly    75 FRTGLNLPDSDIDLVVYYKFWNPRLLHELQNELVSQGVTDPDTVTVLDKASVPVVKFTDLISRIR 139
            |.|||.||.|||||||:.. |....|..|:..|..:.|.|.:::.|||||:||::|..|..:.::
Zfish   215 FSTGLYLPTSDIDLVVFGN-WETLPLWTLEEALRKRKVADENSIKVLDKATVPIIKLMDSHTEVK 278

  Fly   140 FDVTFNSVASGVQAADLIKDFIRHFPELPKLVMVLKQFLSLHGFNEVYNSGGVSSYALTLMVISF 204
            .|::|| |.|||:||:||||:.:.:|.||.||:||||||.....|||: :||:.||:|.||.:||
Zfish   279 VDISFN-VQSGVKAANLIKDYKQQYPVLPYLVLVLKQFLLQRELNEVF-TGGIGSYSLFLMAVSF 341

  Fly   205 LQQHARSNRRLSEHSKLALLLIQFLDYYGRKFDFFKYGISVLGQGGCVEKARLRSTLGENNWQSV 269
            ||.|.|.:.. |.:..|.:|||:|.:.|||.|::.|.||.:...|..|.|..::.::.:....|:
Zfish   342 LQLHCREDVS-SSNPNLGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKSMLDGYRPSM 405

  Fly   270 LCIEDPVTPTNDIGRSSYGVLGVMQGFGAAFVKLSKLVD----------SDSSKIVGPILANIVE 324
            |.||||:.|.||:||||||.:.|.:.|..|:|.||..|.          |:|      ||..|:.
Zfish   406 LYIEDPLQPGNDVGRSSYGAMQVKEAFDYAYVILSHAVSPIAKYYPNNKSES------ILGRIIR 464

  Fly   325 VPQSIINYRAWV--HYNFQHLLTPELPC----------------------ADSLV---------- 355
            |.|.::.||.|:  .:..:....|.|.|                      .||:|
Zfish   465 VTQEVVEYRDWISAQWGQKSSKEPVLNCNANDLTLLVEREELDECNNNLSEDSVVCTSVPRSKVS 529

  Fly   356 ----QPSP-------TGSTSPSASASASEDERSGG 379
                .|||       :.|:|||::||:|.|..|.|
Zfish   530 SNSSSPSPSSPSSPSSSSSSPSSTASSSSDADSDG 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-2	NP_001262941.1	NT_PAP_TUTase	52..161	CDD:143392	52/108 (48%)
Trf4-2	NP_001262941.1	PAP_assoc	221..280	CDD:281779	22/58 (38%)
tent4b	NP_001313625.1	NT_PAP_TUTase	188..298	CDD:143392	52/111 (47%)
tent4b	NP_001313625.1	PAP_assoc	356..416	CDD:281779	22/59 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573461
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	244	1.000	Inparanoid score	I3276
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1016712at2759
OrthoFinder	1	1.000	-	-		FOG0002099
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101092
Panther	1	1.100	-	-	O	PTHR23092
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.760