DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trf4-2 and mtpap

DIOPT Version :9

Sequence 1:	NP_001262941.1	Gene:	Trf4-2 / 42983	FlyBaseID:	FBgn0039251	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_021335997.1	Gene:	mtpap / 563801	ZFINID:	ZDB-GENE-101208-3	Length:	600	Species:	Danio rerio

Alignment Length:	338	Identity:	69/338 - (20%)
Similarity:	129/338 - (38%)	Gaps:	89/338 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 QEIEQFYNYIRSTPTEFCLRAGAVRRIEDVVLSIWPSASVDLFGSFRTGLNLPDSDIDLV----- 89
            ::::.....::.|.....||......:.|:..:.:|...:..|||..........|:|::
Zfish   204 EQLQCLTETLQLTEENISLRFLVCSLLGDIAGAYFPECIIRPFGSTVNSFGKLGCDVDMILDLDG 268

  Fly    90 VYYKFWNP----RLLHELQNELVSQGVTD--------------PDTVTVLD--KASVPVVKFTDL 134
            :|.:....    .|.::::.....:.||.              |..|.|.:  :|..|:|:|...
Zfish   269 IYARSQKKGSGLSLEYQVKTGPSERAVTQSILSVVGKCVDQFGPGCVGVQNILQARCPIVRFAHQ 333

  Fly   135 ISRIRFDVTFNSVASGVQAADLIKDFIRHFPELPKLVMVLKQFLSLHGFNEVYNSGGVSSYALTL 199
            .|..:.|:|.|:..: :::::|:..:....|.:..||..::.:...|..........:::::||:
Zfish   334 PSGFQCDLTANNKVA-MKSSELLFLYGHLDPRVRHLVFSVRCWARAHSITSSIPGAWITNFSLTV 397

  Fly   200 MVISFLQQHARSNRRL--------------------------SEHSKLAL---------LLIQFL 229
            ||:.||||  ||...|                          |:.||:||         ||.:|.
Zfish   398 MVVFFLQQ--RSPAMLPTLDRLKELAGPSDKCVIEGNDCTIVSDLSKIALQKNTDTLEKLLQEFF 460

  Fly   230 DYYGRKFDFFKYGISVLGQGGCVEKARLRSTLGENNWQSVLCIEDPVTPTNDIGRSSYGVLGVMQ 294
            ::|| .|.|.|..|:       :.|.:.:|    ....:.|.|::|...|          |.|.:
Zfish   461 EFYG-NFPFNKASIN-------IRKGKEQS----KPEAAALHIQNPFEAT----------LNVSK 503

  Fly   295 GFGAA----FVKL 303
            ...||    ||||
Zfish   504 NVNAAQLERFVKL 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-2	NP_001262941.1	NT_PAP_TUTase	52..161	CDD:143392	23/133 (17%)
Trf4-2	NP_001262941.1	PAP_assoc	221..280	CDD:281779	16/67 (24%)
mtpap	XP_021335997.1	RRM_SF	89..>139	CDD:327398
		PAP_assoc	206..>511	CDD:332051	65/329 (20%)
		NT_PAP_TUTase	222..359	CDD:143392	25/137 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810