DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trf4-2 and tut7

DIOPT Version :9

Sequence 1:	NP_001262941.1	Gene:	Trf4-2 / 42983	FlyBaseID:	FBgn0039251	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_021332039.1	Gene:	tut7 / 562358	ZFINID:	ZDB-GENE-101209-1	Length:	1155	Species:	Danio rerio

Alignment Length:	361	Identity:	77/361 - (21%)
Similarity:	121/361 - (33%)	Gaps:	132/361 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PAKPWQLPDVVYGNGIPALCLLHQEIEQFYNYIRSTPTEFCL-------RAGAVRRIEDVVLSIW 64
            ||||.              ||      ...:.:.|..|||.|       |...:..||.|:..:.
Zfish   183 PAKPH--------------CL------SVSSALESIVTEFGLNDEDLKQRQNILALIEKVLHPVL 227

  Fly    65 PSASVDLFGSFRTGLNLPDSDIDLVVYY--KFWNPRLLHELQNELVSQGVTDP---------DTV 118
            |.....|:||..|.....|||:::.|.:  .|.:|.:|...|..|....:.|.         ..|
Zfish   228 PECQFRLYGSSSTKFGFKDSDVNIDVKFPSHFQHPDILLAAQEHLSKSSLFDSVEGDFHRRMPVV 292

  Fly   119 TVLDKASVPVVKFTDLISRIRFDVTFNSVASGVQAADLIKDFIRHF----PELPKLVMVLKQFLS 179
            ...:|||..:.|                |::|.::|.|...::...    |:|..||:..:.:..
Zfish   293 VCKEKASGLICK----------------VSAGNESACLTTAYLSEMADLEPQLVPLVICFRYWAK 341

  Fly   180 LHGFNEVYNSGGVSSYALTLMVISFLQQ------------------------------------H 208
            :...::: ..||:.||...||||||||:                                    :
Zfish   342 ICCVDQM-EEGGLPSYCFALMVISFLQRRKEPILPTYLESMGFPLSKLKSFSLTGVEKGHVLWVY 405

  Fly   209 ARSNRRLSEHSK------------------LALLLIQFLDYYGRKFDFFKYGISVLGQGGCVEKA 255
            .::|....:..|                  |..|.|:.|.||..:|...:..|||
Zfish   406 DQTNDSSLDKDKAVKKGKAPLAFKSRSPVLLGKLWIELLRYYALEFQIPEKIISV---------- 460

  Fly   256 RLRSTLGE-----NNW-QSVLCIEDPVTPTNDIGRS 285
               .|.||     .:| :..:.||||.|...::.|:
Zfish   461 ---RTNGELWRDLKDWPKKRIAIEDPFTVQRNVART 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-2	NP_001262941.1	NT_PAP_TUTase	52..161	CDD:143392	27/119 (23%)
Trf4-2	NP_001262941.1	PAP_assoc	221..280	CDD:281779	19/64 (30%)
tut7	XP_021332039.1	PAP_assoc	150..>499	CDD:332051	77/361 (21%)
		NT_PAP_TUTase	211..323	CDD:143392	28/127 (22%)
		NT_PAP_TUTase	733..838	CDD:143392
		PAP_assoc	902..955	CDD:309089
		AIR1	<1009..1088	CDD:331526
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910