DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trf4-2 and tent2

DIOPT Version :9

Sequence 1:	NP_001262941.1	Gene:	Trf4-2 / 42983	FlyBaseID:	FBgn0039251	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001018436.1	Gene:	tent2 / 553626	ZFINID:	ZDB-GENE-050522-536	Length:	489	Species:	Danio rerio

Alignment Length:	311	Identity:	80/311 - (25%)
Similarity:	130/311 - (41%)	Gaps:	77/311 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 EFCLRAGAVRRIEDVVLSIWPSASVDLFGSFRTGLNLPDSDIDL--------------VVYYKFW 95
            |.|..|     ::..:..|:|.|.|.|.||...|.....||.||              .||....
Zfish   184 ESCRAA-----LQTDIQKIFPCAKVFLGGSSLNGFGSRSSDADLCLVIEEGPVNHRKDAVYVLSL 243

  Fly    96 NPRLLHELQNELVSQGVTDPDTVTVLDKASVPVVKFTDLISRIRFDVTFNSVASGVQAADLIKDF 160
            ..:||::|..      :..|..:    :|.||:|||.|.||.:.||:.||:.. |::...|::.:
Zfish   244 VRKLLYKLSY------IEKPQLI----RAKVPIVKFRDRISGVEFDLNFNNTV-GIRNTFLLRTY 297

  Fly   161 IRHFPELPKLVMVLKQFLSLHGFNEVYNSGGVSSYALTLMVISFLQQHARS-------------N 212
            ......:..||:|:|::.:.|..|:. :.|.:|||.|.|||:.:||.....             :
Zfish   298 AFVEKRVRPLVLVIKKWANHHCINDA-SRGTLSSYTLVLMVLHYLQTLPEPVIPCLQRDYPTCFD 361

  Fly   213 RRLSEH-----------------SKLALLLIQFLDYYGRKFDFFKYGISVLGQGGCVEKARLRST 260
            .::..|                 |.|..|.:.||.||...|.:.|..|||          |:..|
Zfish   362 PKMDIHLVPSGPSDIPAFVSRNQSSLGDLFLGFLRYYATVFKWDKQVISV----------RMART 416

  Fly   261 LGENN---WQ-SVLCIEDPVTPTNDIGRSSYGVLGVMQGFGAAFVKLSKLV 307
            |.::|   |: ..:|:|:|...|| ..|:.:..: ..:...|||::..:|:
Zfish   417 LPKSNCKEWKDKFICVEEPFNRTN-TARAVHERM-KFEAIKAAFIESHRLL 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-2	NP_001262941.1	NT_PAP_TUTase	52..161	CDD:143392	33/122 (27%)
Trf4-2	NP_001262941.1	PAP_assoc	221..280	CDD:281779	19/62 (31%)
tent2	NP_001018436.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	93..118
		NT_PAP_TUTase	182..298	CDD:143392	36/129 (28%)
		PAP_assoc	386..440	CDD:281779	19/63 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910