Protein Alignment Trf4-2 and MTPAP

DIOPT Version :9

• Sequence 1: NP_001262941.1
• Gene: Trf4-2 / 42983
• FlyBaseID: FBgn0039251
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_060579.3
• Gene: MTPAP / 55149
• HGNCID: 25532
• Length: 582
• Species: Homo sapiens
• Alignment Length: 361
• Identity: 76/361 - (21%)
• Similarity: 136/361 - (37%)
• Gaps: 105/361 - (29%)

  Fly    56 IEDVVLSIWPSASVDLFGSF-----RTGLNLPDSDIDL-----VVYYKFWNPRLLHELQNELVSQ 110
            |||:..:.:|...|..|||.     :.|.:| |..:||     :..:|.....|:......:.|:
Human   214 IEDMAAAYFPDCIVRPFGSSVNTFGKLGCDL-DMFLDLDETRNLSAHKISGNFLMEFQVKNVPSE 277

  Fly   111 GVTDPDTVTVLDK-----------------ASVPVVKFTDLISRIRFDVTFNSVASGVQAADLIK 158
            .:.....::||.:                 |..|:|:|:...|..:.|:|.|: ...:.:::|:.
Human   278 RIATQKILSVLGECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCDLTTNN-RIALTSSELLY 341

  Fly   159 DFIRHFPELPKLVMVLKQFLSLHGFNEVYNSGGVSSYALTLMVISFLQQHA-------------- 209
            .:......:..||..::.:...|..........:::::||:|||.|||:.:
Human   342 IYGALDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLA 406

  Fly   210 ----------------RSNRRL--SEHSK-LALLLIQFLDYYGRKFDFFKYGISVLGQGGCVEKA 255
                            |...|:  |:::: |.|||.:|.:|:| .|.|.|..|:: .||
Human   407 DAEDKCVIEGNNCTFVRDLSRIKPSQNTETLELLLKEFFEYFG-NFAFDKNSINI-RQG------ 463

  Fly   256 RLRSTLGENNW--QSVLCIEDPVTPTNDIGRSSYGVLGVMQGFGAAFVKLSK-----LVDSDSSK 313
                  .|.|.  .|.|.|::|...:.:|.::      |.|.....||.|::     |...|:.:
Human   464 ------REQNKPDSSPLYIQNPFETSLNISKN------VSQSQLQKFVDLARESAWILQQEDTDR 516

  Fly   314 IVGPILANIVEVPQSIINYRAWVHYNFQHLLTPELP 349
                         .||.:.|.|   ....||.|..|
Human   517 -------------PSISSNRPW---GLVSLLLPSAP 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-2	NP_001262941.1	NT_PAP_TUTase	52..161	CDD:143392	27/131 (21%)
		PAP_assoc	221..280	CDD:281779	19/60 (32%)
MTPAP	NP_060579.3	NT_PAP_TUTase	206..344	CDD:143392	27/131 (21%)
		PAP_assoc	440..483	CDD:281779	17/56 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810