DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trf4-2 and Tut7

DIOPT Version :9

Sequence 1:	NP_001262941.1	Gene:	Trf4-2 / 42983	FlyBaseID:	FBgn0039251	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_006253593.1	Gene:	Tut7 / 501515	RGDID:	1586015	Length:	1550	Species:	Rattus norvegicus

Alignment Length:	330	Identity:	73/330 - (22%)
Similarity:	128/330 - (38%)	Gaps:	89/330 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LPDVV--YGNGIPALCLLHQEIEQFYNYIRSTPTEFCLRAGAVRRIEDVVLSIWPSASVDLFGSF 75
            ||.:.  :.|.:..:|:      |.|.....|..|...|....:.:|..:...:|...:.||||.
  Rat   994 LPPLTPKFSNILDQVCI------QCYKDFSPTIVEDQAREHIRQNLESFIKQDFPGTKLSLFGSS 1052

  Fly    76 RTGLNLPDSDIDLVVYYKFWNPRLLHELQNELVSQGV----TDPDTVTVLDK------------A 124
            :.|.....||:|:.:           .:.....::|:    |..:...||.|            |
  Rat  1053 KNGFGFKQSDLDVCM-----------TINGHETAEGLDCVRTIEELARVLRKHSGLRNILPITTA 1106

  Fly   125 SVPVVKFTDLISRIRFDVT-FNSVASGVQAADLIKDFIRHFPELPKLVMVLKQFLSLHGFNEVYN 188
            .||:|||:.|.|.:..|:: :|::|  :....|:..:....|.:..|...:|.|..:....:. :
  Rat  1107 KVPIVKFSHLRSGLEVDISLYNTLA--LHNTRLLFAYSAIDPRVKYLCYTMKVFTKMCDIGDA-S 1168

  Fly   189 SGGVSSYALTLMVISFLQQHA-----------RSNRR----------------------LSEHSK 220
            .|.:||||.||||:.||||.:           :..::                      ..|:.|
  Rat  1169 RGSLSSYAYTLMVLYFLQQRSPPVIPVLQEIYKGEKKPEILVDGWNIYFFDQINELPTCWPEYGK 1233

  Fly   221 ----LALLLIQFLDYYGRKFDFFKYGISVLGQGGCVEKARLRS--TLGENNWQS-VLCIEDPVTP 278
                :..|.:..|.:|..:|||.::.||:          |.:|  |..:..|.| .:.||||...
  Rat  1234 NTESVGQLWLGLLRFYTEEFDFKEHVISI----------RRKSLLTTFKKQWTSKYIVIEDPFDL 1288

  Fly   279 TNDIG 283
            .:::|
  Rat  1289 NHNLG 1293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-2	NP_001262941.1	NT_PAP_TUTase	52..161	CDD:143392	27/125 (22%)
Trf4-2	NP_001262941.1	PAP_assoc	221..280	CDD:281779	17/61 (28%)
Tut7	XP_006253593.1	TUTase	205..539	CDD:408858
		PAP_assoc	550..599	CDD:397761
		TRF4	983..>1314	CDD:227585	73/330 (22%)
		NT_PAP_TUTase	1025..1142	CDD:143392	28/129 (22%)
		ZnF_C2HC	1347..1362	CDD:197667
		TUTF7_u4	1370..1451	CDD:406924
		ZnF_C2HC	1453..1469	CDD:197667
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910