DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Trf4-2 and Gld2

DIOPT Version :9

Sequence 1:	NP_001262941.1	Gene:	Trf4-2 / 42983	FlyBaseID:	FBgn0039251	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001262829.1	Gene:	Gld2 / 42602	FlyBaseID:	FBgn0038934	Length:	1364	Species:	Drosophila melanogaster

Alignment Length:	475	Identity:	111/475 - (23%)
Similarity:	175/475 - (36%)	Gaps:	148/475 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCDEANPAKPW------QLPDVVYGNGIPALCLLHQEIEQFYNYIRSTPTE-FCLRA-------- 50
            |..::|...|.      :||.||:          ::...:|:.|   ||.: |.|||
  Fly   872 MASKSNITMPEENNDDDELPLVVH----------NRYWREFFGY---TPADRFLLRAKFVEMRRP 923

  Fly    51 ----GAVRRIEDVVLSIW-------------------------------PSASVDLFGSFRTGLN 80
                |...:.:.:.||:|                               |...:.|.||..:...
  Fly   924 PKVMGCKNKWDPLSLSVWKKFLESQQTRHVYKIKMRLWRAIYTVAMKNYPRYGLYLVGSSISYFG 988

  Fly    81 LPDSDIDLVVYYKFWNPRL---------LHELQNELVSQGVTDPDTVTVLDKASVPVVKFTDLIS 136
            ...||:|:.: ....||.:         ||.::..|   |.|:......|.:|.||:::|||...
  Fly   989 SKCSDMDICM-LACTNPNIDSRMEAVYHLHVMKELL---GRTNMFQDFNLIEARVPILRFTDRCH 1049

  Fly   137 RIRFDVTFNSVASGVQAADLIKDFIRHFPELPKLVMVLKQFLSLHGFNEVYNSGGVSSYALTLMV 201
            ::..|:.||: :.|::...|:..:.:....:..:.:.:||:...|..|...|. .:|||:|.|||
  Fly  1050 KVEVDINFNN-SVGIRNTHLLYCYSQLDWRVRPMALTVKQWAQYHNINNAKNM-TISSYSLMLMV 1112

  Fly   202 ISFLQQHAR---------------------------SNRRL----SEHSK-LALLLIQFLDYYGR 234
            |.|||..|.                           .|..:    |::|: |..||:.||.||.
  Fly  1113 IHFLQVGASPPVLPCLHNLYPEKFGLLQPNDFGYVDMNEVMAPYQSDNSQTLGDLLLSFLHYYS- 1176

  Fly   235 KFDFFKYGISVLGQGGCVEKARLRSTLGENN----WQSVLCIEDPVTPTNDIGRSSYGVLGVMQG 295
            .||:.||.||: ..||.:.....|:.....|    |.. ||||:|...|| ..||.|.. ...:.
  Fly  1177 VFDYGKYAISI-RVGGVLPIEVCRAATAPKNDIHQWNE-LCIEEPFDQTN-TARSVYDT-DTFER 1237

  Fly   296 FGAAFVKLSKLVDSDSSKIVGPILANIVEVPQSIINYRAWVHYNFQHLLTPELPCADSLVQ---- 356
            ....||...:.:||..:      |:.|.|            .|:...:|..: |..||.::
  Fly  1238 IKTIFVASYRRLDSTRN------LSAIFE------------DYDGPTILMQQ-PSVDSEIELYEG 1283

  Fly   357 ------PSPTGSTSPSASAS 370
                  |:...|.|.||..|
  Fly  1284 QHHRLLPNRGSSRSNSAIPS 1303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-2	NP_001262941.1	NT_PAP_TUTase	52..161	CDD:143392	29/148 (20%)
Trf4-2	NP_001262941.1	PAP_assoc	221..280	CDD:281779	23/62 (37%)
Gld2	NP_001262829.1	NT_PAP_TUTase	954..1073	CDD:143392	26/123 (21%)
Gld2	NP_001262829.1	PAP_assoc	1163..1224	CDD:281779	23/63 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810