DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trf4-2 and Mtpap

DIOPT Version :9

Sequence 1:	NP_001262941.1	Gene:	Trf4-2 / 42983	FlyBaseID:	FBgn0039251	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_038951672.1	Gene:	Mtpap / 307050	RGDID:	1310900	Length:	584	Species:	Rattus norvegicus

Alignment Length:	379	Identity:	80/379 - (21%)
Similarity:	149/379 - (39%)	Gaps:	101/379 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DEANPAKPWQLPDVV-YGNGIPALCLLHQEIEQFYNYIRSTPTEFCLRAGAVRRIEDVVLS---- 62
            |..:|....:|.::: |...|.|      ::.......:.|.....||......|||:..:
  Rat   169 DSQSPPSSKKLFELLSYAESIDA------QLTALLKAFQLTEENVRLRHLTCSLIEDIAAAYFPS 227

  Fly    63 --IWP-SASVDLFGSFRTGLNLPDSDIDL-----VVYYKFWNPRLLHELQNELVSQGVTDPDTVT 119
              :|| .:||:.||  :.|.:| |..:||     :..:|.....|:......:.|:.|.....::
  Rat   228 CVVWPFGSSVNTFG--KLGCDL-DMFLDLDETGNLSDHKNTGNFLMEFQVKNVPSERVATQKILS 289

  Fly   120 VLDK-----------------ASVPVVKFTDLISRIRFDVTF-NSVASGVQAADLIKDFIRHFPE 166
            |:.:                 |..|:|:|:...|..:.|:|. ||:|  :::::|:..:......
  Rat   290 VIGECLDNFGPGCVGVQKILNARCPLVRFSHQGSGFQCDLTANNSIA--LKSSELLYIYGSLDSR 352

  Fly   167 LPKLVMVLKQFLSLHGFNEVYNSGGVSSYALTLMVISFLQQHA---------------RSNRRLS 216
            :..||..::.:...|..........:::::||:|||.|||:.:               ..:|.:.
  Rat   353 VRALVFGVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKSMADAEDRCIL 417

  Fly   217 EHSK------------------LALLLIQFLDYYGRKFDFFKYGISVLGQGGCVEKARLRSTLGE 263
            |.:.                  |.|||.:|.:|:| .|.|.|..|:: .||            .|
  Rat   418 EGNNCTFIQDINKIKPSGNTETLELLLKEFFEYFG-NFAFNKNSINI-RQG------------RE 468

  Fly   264 NNW--QSVLCIEDPVTPTNDIGRSSYGVLGVMQGFGAAFVKLSKLVDSDSSKIV 315
            .|.  .|.|.|::|...:.:|.::      |.|.....||:|::    ||:.|:
  Rat   469 QNKPDSSPLYIQNPFETSLNISKN------VSQNQLQKFVELAR----DSAWIL 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-2	NP_001262941.1	NT_PAP_TUTase	52..161	CDD:143392	30/138 (22%)
Trf4-2	NP_001262941.1	PAP_assoc	221..280	CDD:281779	19/60 (32%)
Mtpap	XP_038951672.1	RL	63..132	CDD:407669
		TRF4	184..>496	CDD:227585	70/342 (20%)
		NT_PAP_TUTase	209..347	CDD:143392	32/142 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810