Protein Alignment Trf4-2 and Tent4b

DIOPT Version :9

• Sequence 1: NP_001262941.1
• Gene: Trf4-2 / 42983
• FlyBaseID: FBgn0039251
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_001359262.1
• Gene: Tent4b / 214627
• MGIID: 1917820
• Length: 700
• Species: Mus musculus
• Alignment Length: 429
• Identity: 160/429 - (37%)
• Similarity: 227/429 - (52%)
• Gaps: 62/429 - (14%)

  Fly    10 PWQLPDVVYGNGIPALCLLHQEIEQFYNYIRSTPTEFCLRAGAVRRIEDVVLSIWPSASVDLFGS 74
            ||:..:  |..|:..   ||:||..||.|:...|.|..:|...|.|||.|:..:||||.|.:|||
Mouse   188 PWKRRN--YNQGVVG---LHEEISDFYEYMSPRPEEEKMRMEVVSRIESVIKELWPSADVQIFGS 247

  Fly    75 FRTGLNLPDSDIDLVVYYKFWNPRLLHELQNELVSQGVTDPDTVTVLDKASVPVVKFTDLISRIR 139
            |:|||.||.|||||||:.| |....|..|:..|....|.|.|:|.|||||:||::|.||..:.::
Mouse   248 FKTGLYLPTSDIDLVVFGK-WENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVK 311

  Fly   140 FDVTFNSVASGVQAADLIKDFIRHFPELPKLVMVLKQFLSLHGFNEVYNSGGVSSYALTLMVISF 204
            .|::|| |.:||:||||||||.:.:|.||.||:||||||.....|||: :||:.||:|.||.:||
Mouse   312 VDISFN-VQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVF-TGGIGSYSLFLMAVSF 374

  Fly   205 LQQHARSNRRLSEHSKLALLLIQFLDYYGRKFDFFKYGISVLGQGGCVEKARLRSTLGENNWQSV 269
            ||.|.|.:..: .::...:|||:|.:.|||.|::.|.||.:...|..|.|..::..:.:....|:
Mouse   375 LQLHPREDACI-PNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSM 438

  Fly   270 LCIEDPVTPTNDIGRSSYGVLGVMQGFGAAFVKLSKLV--------DSDSSKIVGPILANIVEVP 326
            |.||||:.|.||:||||||.:.|.|.|..|:|.||..|        ::::..|:|    .|:.|.
Mouse   439 LYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKYYPNNETESILG----RIIRVT 499

  Fly   327 QSIINYRAWVHYNFQHLLTPELPC-----------------------------------ADSLVQ 356
            ..:..||.|:...:.....||..|                                   ::.|.:
Mouse   500 DEVATYRDWISKQWGLQNRPEPSCNGNGVTLIVDTQQLDKCNNNLSEEKEALGKCRSNASEPLSK 564

  Fly   357 PSPTGSTSPSASASASEDERS--GGPATIGFGRCDDPPQ 393
            .|...|:.|.:|:||::...|  ...||    .|..|.|
Mouse   565 HSSNSSSGPVSSSSATQSSSSDVDSDAT----PCKTPKQ 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-2	NP_001262941.1	NT_PAP_TUTase	52..161	CDD:143392	58/108 (54%)
		PAP_assoc	221..280	CDD:281779	21/58 (36%)
Tent4b	NP_001359262.1	TRF4	201..>473	CDD:227585	130/275 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830721
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I3179
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002099
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101092
Panther	1	1.100	-	-	O	PTHR23092
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2219
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.780