DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trf4-2 and cid-1

DIOPT Version :9

Sequence 1:	NP_001262941.1	Gene:	Trf4-2 / 42983	FlyBaseID:	FBgn0039251	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_498099.1	Gene:	cid-1 / 175707	WormBaseID:	WBGene00019629	Length:	1425	Species:	Caenorhabditis elegans

Alignment Length:	358	Identity:	87/358 - (24%)
Similarity:	141/358 - (39%)	Gaps:	118/358 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EANPAKPWQ------------LPDVVYGNGI---PALCLLHQEIEQFYNYIRSTPTEFCLRAGAV 53
            |..|.|.:|            :.|..|...|   ..|.:|..:|::..:::|....
Worm   991 EIPPIKKYQARTPEDLKDIDDMIDKYYHENILDERRLKMLDHKIDELQSFLRKNYR--------- 1046

  Fly    54 RRIEDVVLSIWPSASVDLFGSFRTGLNLPDSDIDLVVYYKFWN----PRLLHELQNELVSQGVTD 114
               |||.|:        .|||..|||::..||||:.:  :|.:    |:       :|.::.|..
Worm  1047 ---EDVTLT--------TFGSVMTGLSVNCSDIDICL--RFGDGDVPPK-------DLTAKEVIQ 1091

  Fly   115 PDTVTVLDK------------ASVPVVKFTDLISR---IRFDVTFNSVASGVQAADLIKDFIRHF 164
             .|.:||.|            |.||:|||...:|.   |..|:::.::.:....| |:|::....
Worm  1092 -KTESVLRKCHLVKRVQAIVTAKVPIVKFQVKLSNGAIIDVDISYYNILAIYNTA-LLKEYSLWT 1154

  Fly   165 PE--LPKLVMVLKQFLSLHGFNEVYNSGGVSSYALTLMVISF-----------LQQHARSN---R 213
            |:  ..||.:.:|.:.......:. :.|.:|||...:|:||:           ||:..||:   |
Worm  1155 PDKRFAKLALFVKTWAKNCEIGDA-SRGSLSSYCHVIMLISYLQNCDPPVLPRLQEDFRSDNRER 1218

  Fly   214 RLSEH--------------------SKLALLLIQFLDYYGRKFDFFKYGISVLGQGGCVEKARLR 258
            ||.::                    ...|.|||.:.|||.| |||..:          |.:.|..
Worm  1219 RLVDNWDTSFAQVETSLLQRWPKNKESCAQLLIGYFDYYSR-FDFRNF----------VVQCRRE 1272

  Fly   259 STLG--ENNWQSVLCIEDPVTPTNDIGRSSYGV 289
            ..|.  |..|...||:|||...::::   |.||
Worm  1273 MILSKMEKEWPRPLCVEDPFDLSHNL---SSGV 1302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-2	NP_001262941.1	NT_PAP_TUTase	52..161	CDD:143392	34/127 (27%)
Trf4-2	NP_001262941.1	PAP_assoc	221..280	CDD:281779	21/60 (35%)
cid-1	NP_498099.1	PAP_assoc	574..625	CDD:367682
		NT_PAP_TUTase	1029..1151	CDD:143392	37/152 (24%)
		TRF4	1034..>1317	CDD:227585	78/315 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810