Protein Alignment Trf4-2 and gld-4

DIOPT Version :9

• Sequence 1: NP_001262941.1
• Gene: Trf4-2 / 42983
• FlyBaseID: FBgn0039251
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_492446.3
• Gene: gld-4 / 172735
• WormBaseID: WBGene00014115
• Length: 845
• Species: Caenorhabditis elegans
• Alignment Length: 403
• Identity: 129/403 - (32%)
• Similarity: 190/403 - (47%)
• Gaps: 36/403 - (8%)

  Fly     7 PAKPWQLPDVVYGNGIPALCLLHQEIEQFYNYIRSTPTEFCLRAGAVRRIEDVVLSIW--PSASV 69
            |..||:...  ||..|..   ||:||...|::|:....|..||.....::.|.||..|  .:..:
 Worm    64 PFAPWRRKR--YGLNIQG---LHEEIVDMYHWIKPNEIESRLRTKVFEKVRDSVLRRWKQKTIKI 123

  Fly    70 DLFGSFRTGLNLPDSDIDLVVYYKFW--NP-RLLHELQNELVSQGVTDPDTVTVLDKASVPVVKF 131
            .:|||.||.|.||.||||::|....|  .| ..|.|....|.:..:.  ::|.|...|.||:||.
 Worm   124 SMFGSLRTNLFLPTSDIDVLVECDDWVGTPGDWLAETARGLEADNIA--ESVMVYGGAFVPIVKM 186

  Fly   132 TDLISRIRFDVTFNSVASGVQAADLIKDFIRHFPELPKLVMVLKQFLSLHGFNEVYNSGGVSSYA 196
            .|..:|:..|::||:| .||:||..|......||.:..||::|||||.....|:.: :||:|||.
 Worm   187 VDRDTRLSIDISFNTV-QGVRAASYIAKVKEEFPLIEPLVLLLKQFLHYRNLNQTF-TGGLSSYG 249

  Fly   197 LTLMVISFLQQHARSNRRLSEHSK---LALLLIQFLDYYGRKFDFFKYGISVLGQGGCVEKARLR 258
            |.|::::|.|.:|.:.|..:.:.:   |..||::||:.|..:|:|.:.|||. ||...:.|:...
 Worm   250 LVLLLVNFFQLYALNMRSRTIYDRGVNLGHLLLRFLELYSLEFNFEEMGISP-GQCCYIPKSASG 313

  Fly   259 STLGENNWQ-SVLCIEDPVTPTNDIGRSSYGVLGVMQGFGAAFVKLSKLVDSDSSK--------- 313
            :..|....| ..|.:|||:...||:|||:|....:...||.||..|...|.....|
 Worm   314 ARYGHKQAQPGNLALEDPLLTANDVGRSTYNFSSIANAFGQAFQILLVAVTLRERKGKNHVAMRA 378

  Fly   314 IVGPILANIVEVPQSIINYRAWVHYNFQHLLTPELPCADSLVQ-----PSPTGSTSPSA---SAS 370
            ..|.:|..|:......:.||.|:......:...|.|.:..|.|     .||....|..|   .|.
 Worm   379 YKGSLLHLIMPFTSKELTYRNWLMSGVLSMPGQEAPASYDLNQLHNTLVSPMVDLSRYAWLRKAP 443

  Fly   371 ASEDERSGGPATI 383
            |..::|...|.||
 Worm   444 AKAEKRDSRPLTI 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-2	NP_001262941.1	NT_PAP_TUTase	52..161	CDD:143392	40/113 (35%)
		PAP_assoc	221..280	CDD:281779	20/59 (34%)
gld-4	NP_492446.3	NT_PAP_TUTase	100..213	CDD:143392	42/115 (37%)
		PAP_assoc	276..336	CDD:281779	20/60 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159360
Domainoid	1	1.000	66	1.000	Domainoid score	I6526
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002099
OrthoInspector	1	1.000	-	-		otm14320
orthoMCL	1	0.900	-	-		OOG6_101092
Panther	1	1.100	-	-	O	PTHR23092
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2219
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730