DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PIG-S and AT3G07180

DIOPT Version :9

Sequence 1:	NP_733060.1	Gene:	PIG-S / 42979	FlyBaseID:	FBgn0265190	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_187374.2	Gene:	AT3G07180 / 819905	AraportID:	AT3G07180	Length:	599	Species:	Arabidopsis thaliana

Alignment Length:	577	Identity:	143/577 - (24%)
Similarity:	229/577 - (39%)	Gaps:	115/577 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 IGVPMWWRTTTVYRVNLPSTEILSLS----KIPIK-----TAVQVAIYTQQTS--RGQLLIAELQ 89
            :|||..|::..:||..||..:|.|||    ..|::     .||.|...:....  |.|:.....|
plant    43 LGVPFLWKSVEIYRSPLPFHDIDSLSDQLESTPLRFPCNFHAVFVGFRSTDPDNLRSQIQDGINQ 107

  Fly    90 NAFSDNEIWSVEFKQLSPTPMTQE-------AH--TPAALEKLLLENHVQSVG-DFMFIEWPKLQ 144
            .....::..|.:| .||.|...:|       ||  |..:....:::.:..||| |....|  .|.
plant   108 LTHQSSQCGSCDF-SLSVTVQNREDQCSDTLAHSSTTCSYRCGVIKRNGFSVGLDDTVDE--SLN 169

  Fly   145 EELLLTTERSALMRSDTPSNK------------IAQLLHAKIL-----QTY-----RINQILSTD 187
            :.....:|.|..|.|....||            :.:..||.|:     :.|     |:::|....
plant   170 DVFSGCSENSGKMYSVVVVNKENANGGDEVKAVVGKRRHAWIVGNGLEERYGDIVARVSEIFVQV 234

  Fly   188 ERMGAKSE-------APQPAYDVIV---SVLNPKPRLTHAKWNIAMAVKTYIEPWLAKVSGVSNY 242
            ...|.:.|       .|..:...||   |:||..||.....|:.....:..:.|....::.::|.
plant   235 FMNGGREEDSIQGEFMPVGSDGKIVLSFSLLNSNPRDWVYDWDFQRIDEALLAPVTKALAPIANI 299

  Fly   243 TVRSQWKYRVAIEADLKQVRDQSKLGRHYALQETALPHLLTSIAQNL--SASTTDKPAI-NLVVY 304
            ||.||    |.............|..:.|..:.:.||..:.|...:|  ||..:.:..| ..|||
plant   300 TVESQ----VLYHTPKSSFSSWDKKLQSYIFRTSDLPFFVNSNEWHLDTSAGASGRSKILQFVVY 360

  Fly   305 IPPCHIAPL-----HIYNSKDQRLTRNDVDAFISPPWGGFIIANP---------PEHVCLAAMSD 355
            ||.....||     ::..||        .:.||||.|||.|:.||         |....: ::.|
plant   361 IPSGKECPLLLQLPNVEISK--------TNGFISPMWGGVIVWNPGNCDKDSESPSRNTI-SLQD 416

  Fly   356 QEAVPYHVSTTDNMQVMLDQLHKLLDISSELQ----MEGVKVVDIEQLEPRRWEYEAYLRRSAIR 416
            .|.:         :::.|.|..:|....||.:    :...|::..|: ....||.:...|:....
plant   417 LEQI---------VEIFLGQFRQLFGFKSEAKYTTGLGTYKILTSER-GFTEWELDVLSRKHTCF 471

  Fly   417 HISTASSTLQSLIKLLDQISYIVIDDEVGAAITNSYADILAAKAALLEHRLADASVLA---KRAF 478
            ::.:.|:||.||.:|:..:..::|.||:|..:..|   :.|||.|.....|...|..|   :.|.
plant   472 NLHSCSTTLGSLSRLVRSLPRMIIKDEIGEQVKYS---LKAAKLAQSNASLGGYSSSASSSREAR 533

  Fly   479 VASERGFFDASLLAQLYFPDEQKYAIYIPLFLPIMVPVLSSFNMLRGVLQARRKEKQ 535
            ..:|..||..|:::..||..|..:|:|.|.|||::..|         ||.|.|:.|:
plant   534 SLAENAFFHPSIMSVSYFSYEHCFAVYSPFFLPVVGHV---------VLAAVREWKR 581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIG-S	NP_733060.1	PIG-S	28..521	CDD:287481	138/561 (25%)
AT3G07180	NP_187374.2	PIG-S	35..585	CDD:287481	143/577 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	113	1.000	Domainoid score	I2049
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41963
Inparanoid	1	1.050	113	1.000	Inparanoid score	I2049
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1399804at2759
OrthoFinder	1	1.000	-	-		FOG0004772
OrthoInspector	1	1.000	-	-		oto3336
orthoMCL	1	0.900	-	-		OOG6_103860
Panther	1	1.100	-	-	LDO	PTHR21072
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3925
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.970