Protein Alignment PIG-S and pigs-1

DIOPT Version :9

• Sequence 1: NP_733060.1
• Gene: PIG-S / 42979
• FlyBaseID: FBgn0265190
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001369906.1
• Gene: pigs-1 / 3565629
• WormBaseID: WBGene00011776
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 558
• Identity: 119/558 - (21%)
• Similarity: 215/558 - (38%)
• Gaps: 130/558 - (23%)

  Fly    18 EDKFRIGATLAFIVVIIGIGVPMWWRTTTVYRVNLPSTEILSLSKIPIKTAVQVAIYTQQTSRGQ 82
            |..:::.|:|:|::::..||:|||..||:.||.|.|:........:||:.   :.:.|.:..|..
 Worm    47 ERPYKLAASLSFVILVFFIGMPMWHFTTSTYRSNFPTFPSNQSITVPIRV---IFVITSEDLRND 108

  Fly    83 L--LIAELQNAFSDNEI-------WSVEFKQLSPTPMTQEAHTPAALEK---------LLLE--- 126
            :  |:.||:...:..|:       |:.:|..|......::.|:....|.         |:.|
 Worm   109 VKTLMNELEVNMTKKEVVAPLDFTWTTQFIGLRSFEHLEQDHSIQIEENKEFFDVFVALVPEKEW 173

  Fly   127 -----NHVQ-SVGDFMFIEWPKLQEELLLTTERSALMRSDTPSNKIAQLLHAKILQTYRINQILS 185
                 ..:| .:|.:.||:||...||            ....|.::..|:...::....:|.|:.
 Worm   174 THYSATRIQLGIGKWNFIQWPTKSEE------------KQKASTRVTDLVSETLIDVPHLNSIVR 226

  Fly   186 TDERMGAKSEAPQPAYDVIVSVLNPKPRLTHAKWNIAMAVKTY---------------------- 228
            .|.|     :..|| :.:....|:.:.||.   |:.|.....|
 Worm   227 RDLR-----QKMQP-WQIAALPLSHQKRLV---WDSAPLATNYHIQVIHLHENSEITPESLKEQE 282

  Fly   229 -----IEPWLAKVSGVSNYTVRSQ--WKYRVAIEADLKQVRDQSKLGRHYALQETALPHLLTSIA 286
                 :..:..||..::|..|..:  |.:.......:|.|:::      :||..:|:..|:..:.
 Worm   283 KTARALRKFAEKVKEITNVEVSFEHLWDFEPTRGFLIKDVQER------WALTHSAMEELVKKVD 341

  Fly   287 QNLSASTTDKPAINLVVYIPPCHIAPLHIYNSKDQRLTRNDVDAFISPPWGGFIIANPPEHVCLA 351
            ..|..|......:..||...   :.|:.:.:.     |..|........||             |
 Worm   342 SQLQTSLQHGAVLRFVVLET---VEPVIVLDD-----TGEDSHGVAVASWG-------------A 385

  Fly   352 AMSDQEAVPYHVSTTDNMQVMLDQLHKLLDISSELQMEGVKVVDIEQLEPRRWEYEAYLRRSAIR 416
            .:...||..........:|:.:|     .::|.......|.:.        :||......|:::.
 Worm   386 VLPRNEATESRAIAAIRIQMGMD-----AELSHGWHRPPVAIC--------QWEVARARLRASVD 437

  Fly   417 HISTASSTLQSLIKLLDQISYIVIDDEVGAAITNSYA---DILAAKAALLEHRLADASVLAKRAF 478
            :...|:|.:::|.:|..:||.|||:|:|....|.:..   |::.....|...||.:|..||..|
 Worm   438 NAMRAASAVRALDQLAQKISNIVINDDVADRATRAVEILNDVVRPGRMLDFERLLEARRLADSA- 501

  Fly   479 VASERGFFDASLLAQLYFPDEQKYAIYIPLFLPIMVPV 516
                  ..|.||||.||||.:|:.|:.|||.:||::|:
 Worm   502 ------NSDHSLLAMLYFPMDQRTAVLIPLAVPIVLPI 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-S	NP_733060.1	PIG-S	28..521	CDD:287481	116/548 (21%)
pigs-1	NP_001369906.1	PIG-S	57..542	CDD:402233	116/548 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158373
Domainoid	1	1.000	82	1.000	Domainoid score	I5459
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I3699
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46691
OrthoDB	1	1.010	-	-		D1399804at2759
OrthoFinder	1	1.000	-	-		FOG0004772
OrthoInspector	1	1.000	-	-		oto18557
orthoMCL	1	0.900	-	-		OOG6_103860
Panther	1	1.100	-	-	LDO	PTHR21072
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R923
SonicParanoid	1	1.000	-	-		X3925
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.940