Protein Alignment CG11069 and PDR12

DIOPT Version :10

• Sequence 1: NP_651307.2
• Gene: CG11069 / 42976
• FlyBaseID: FBgn0039244
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_015267.1
• Gene: PDR12 / 856049
• SGDID: S000005979
• Length: 1511
• Species: Saccharomyces cerevisiae
• Alignment Length: 705
• Identity: 162/705 - (22%)
• Similarity: 263/705 - (37%)
• Gaps: 227/705 - (32%)

  Fly     2 KMIGSDYVLEAHNIFHTTEVDGGGCFNGAGNSALVLKGVNLTVHSGEVMAILGSKGSGKRALLDV 66
            |:|....|...:::.:|...||.        :..:|..|...|..|::.|::|..|:||..||:|
Yeast   834 KVIAEKDVFTWNHLDYTIPYDGA--------TRKLLSDVFGYVKPGKMTALMGESGAGKTTLLNV 890

  Fly    67 ISRRAD-GATRGQVLLNGSPLSKALFQQRCGYVTQSCTFVPGLTVAQTLHYTPTILSGYL----- 125
            :::|.: |...|.:|:|..|| .|.|.:.||||.|:...:..|:|.::|.:...:.....
Yeast   891 LAQRINMGVITGDMLVNAKPL-PASFNRSCGYVAQADNHMAELSVRESLRFAAELRQQSSVPLEE 954

  Fly   126 KSSKVRQVLADLALSQVAH----KRVEYLNISEARRLAIGIQLVRDPVMLL-LDEPTHGLDPLSA 185
            |...|.:::..|.:...|.    |....||:.:.::|:||::||..|.:|| |||||.|||..||
Yeast   955 KYEYVEKIITLLGMQNYAEALVGKTGRGLNVEQRKKLSIGVELVAKPSLLLFLDEPTSGLDSQSA 1019

  Fly   186 YLLISILSNTAKKTGCGILLSLEKPRSDVFPFLDRALFLCLGG-VVYSG----GTRAMLEYF-HG 244
            :.::..:...| .:|..||.::.:|.:.:|...||.|.|..|| :||.|    .:..:|:|| ..
Yeast  1020 WSIVQFMRALA-DSGQSILCTIHQPSATLFEQFDRLLLLKKGGKMVYFGDIGPNSETLLKYFERQ 1083

  Fly   245 IGFPCPQLENPLMYYL-CL-----STVDRRSRDRFLESSQ--QIEALVERFSRETP---ISDAP- 297
            .|..|...|||..|.| |:     ::|:....|.:|.|.:  ...|.||...|..|   ::|.|
Yeast  1084 SGMKCGVSENPAEYILNCIGAGATASVNSDWHDLWLASPECAAARAEVEELHRTLPGRAVNDDPE 1148

  Fly   298 ------LNNMGSGKVPLAYGKPGELKVW-VMLYLKLLASTFSC-------GL--VGM-------- 338
                  .:.|...|..|   :...|:.| ..:|::  |..|.|       ||  ||:
Yeast  1149 LATRFAASYMTQIKCVL---RRTALQFWRSPVYIR--AKFFECVACALFVGLSYVGVNHSVGGAI 1208

  Fly   339 ---KTLFLRLLLLPLAL---------------------------SIL----------WA------ 357
               .::|: |||:.||:                           |:|          |:
Yeast  1209 EAFSSIFM-LLLIALAMINQLHVFAYDSRELYEVREAASNTFHWSVLLLCHAAVENFWSTLCQFM 1272

  Fly   358 ----FYTDV---GDDSHG--FFTKNGMILNILGLSYG---------------------------C 386
                :|...   |..||.  ||....:|..:..::||                           |
Yeast  1273 CFICYYWPAQFSGRASHAGFFFFFYVLIFPLYFVTYGLWILYMSPDVPSASMINSNLFAAMLLFC 1337

  Fly   387 GILTTISLFP-IWRK------KFS-------------------------QDTPEGLYSG------ 413
            |||......| .||:      .|:                         .|.|.|...|
Yeast  1338 GILQPREKMPAFWRRLMYNVSPFTYVVQALVTPLVHNKKVVCNPHEYNIMDPPSGKTCGEFLSTY 1402

  Fly   414 ----TTLLI----AYNSVSIPFSAVSAVIASCVVYPLLLDVKYNN-GTVFAYLLVALWSSFVLAE 469
                |..|:    ..|....|::....|:|.   |.:..|.::.| |.::||:      .|.:|.
Yeast  1403 MDNNTGYLVNPTATENCQYCPYTVQDQVVAK---YNVKWDHRWRNFGFMWAYI------CFNIAA 1458

  Fly   470 QLTIAFLLVVKVPFNAAIAVTYVLVISIALASGTVRSFKGLQPWLQDNTKGTHTR 524
            .|...:::.|||                    .:::|....:.|.....|..|.:
Yeast  1459 MLICYYVVRVKV--------------------WSLKSVLNFKKWFNGPRKERHEK 1493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	71/229 (31%)
		ABC2_membrane	364..515	CDD:473876	39/226 (17%)
PDR12	NP_015267.1	3a01205	89..1468	CDD:273362	155/658 (24%)