Protein Alignment CG11069 and PDR5

DIOPT Version :10

• Sequence 1: NP_651307.2
• Gene: CG11069 / 42976
• FlyBaseID: FBgn0039244
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_014796.3
• Gene: PDR5 / 854324
• SGDID: S000005679
• Length: 1511
• Species: Saccharomyces cerevisiae
• Alignment Length: 603
• Identity: 145/603 - (24%)
• Similarity: 253/603 - (41%)
• Gaps: 95/603 - (15%)

  Fly    36 VLKGVNLTVHSGEVMAILGSKGSGKRALLDVISRRAD-GATRGQVLLNGSPLSKALFQQRCGYVT 99
            :|..|:..|..|.:.|::|:.|:||..|||.::.|.. |...|.:|:||.|..|: |.:..||..
Yeast   887 ILNNVDGWVKPGTLTALMGASGAGKTTLLDCLAERVTMGVITGDILVNGIPRDKS-FPRSIGYCQ 950

  Fly   100 QSCTFVPGLTVAQTLHYT-----PTILSGYLKSSKVRQVLADLALSQVAHKRV----EYLNISEA 155
            |....:...||.::|.::     |..:|...|:..|.:|:..|.:.:.|...|    |.||:.:.
Yeast   951 QQDLHLKTATVRESLRFSAYLRQPAEVSIEEKNRYVEEVIKILEMEKYADAVVGVAGEGLNVEQR 1015

  Fly   156 RRLAIGIQLVRDPVMLL-LDEPTHGLDPLSAYLLISILSNTAKKTGCGILLSLEKPRSDVFPFLD 219
            :||.||::|...|.:|: |||||.|||..:|:.:..::...|.. |..||.::.:|.:.:....|
Yeast  1016 KRLTIGVELTAKPKLLVFLDEPTSGLDSQTAWSICQLMKKLANH-GQAILCTIHQPSAILMQEFD 1079

  Fly   220 RALFLCLGG-VVYSG----GTRAMLEYF--HGIGFPCPQLENPLMYYLCL---STVDRRSRD--- 271
            |.||:..|| .||.|    |.:.|::||  || ...||...||..:.|.:   :.....::|
Yeast  1080 RLLFMQRGGKTVYFGDLGEGCKTMIDYFESHG-AHKCPADANPAEWMLEVVGAAPGSHANQDYYE 1143

  Fly   272 --RFLESSQQIEALVERFSRETPISDAPLNNMGSGKVPLAYGKPGELKVWVMLYLKLLASTFSCG 334
              |..|..:.:::.::...||.|         ..|.:..|..| .|....::...||::.
Yeast  1144 VWRNSEEYRAVQSELDWMERELP---------KKGSITAAEDK-HEFSQSIIYQTKLVSI----- 1193

  Fly   335 LVGMKTLFLRLLLLPLALSILWAFY--TDVGDDSHGF-FTKNGMILNILGLSYGCGILTTISLFP 396
                 .||.:....|   ..||:.:  |.......|| |.|.|..|..|........:.|:...|
Yeast  1194 -----RLFQQYWRSP---DYLWSKFILTIFNQLFIGFTFFKAGTSLQGLQNQMLAVFMFTVIFNP 1250

  Fly   397 IWRKKF-----------SQDTPEGLYSGTTLLIAYNSVSIPFSAVSAVIASCV-VYPLLLDVKYN 449
            |.::..           :::.|...:|..:.:.|...|.:|::.::..||..: .||:..   |:
Yeast  1251 ILQQYLPSFVQQRDLYEARERPSRTFSWISFIFAQIFVEVPWNILAGTIAYFIYYYPIGF---YS 1312

  Fly   450 NGTVFAYL--LVALWSSFVLAEQLTIAFLLVVKVPFN-----AAIAVTYVLVISIALASGTVRSF 507
            |.:....|  ..||:..|..|..:.:..:.::.:.||     ||...:.:..:|::...  |.:.
Yeast  1313 NASAAGQLHERGALFWLFSCAFYVYVGSMGLLVISFNQVAESAANLASLLFTMSLSFCG--VMTT 1375

  Fly   508 KGLQP--WLQDNTKGTHTRYASSLLHSIAFQSRKLNC--------TPTASVICPKPADFMHERLG 562
            ....|  |:........|.:..:|| ::...:..:.|        ||.:.:.|   ..:|...|.
Yeast  1376 PSAMPRFWIFMYRVSPLTYFIQALL-AVGVANVDVKCADYELLEFTPPSGMTC---GQYMEPYLQ 1436

  Fly   563 LPDPDETIDVAA--SCAF 578
            |.......|..|  :|:|
Yeast  1437 LAKTGYLTDENATDTCSF 1454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	67/208 (32%)
		ABC2_membrane	364..515	CDD:473876	34/172 (20%)
PDR5	NP_014796.3	ABC_trans_N	46..152	CDD:464194
		3a01205	100..1503	CDD:273362	145/603 (24%)