Protein Alignment CG11069 and PDR15

DIOPT Version :10

• Sequence 1: NP_651307.2
• Gene: CG11069 / 42976
• FlyBaseID: FBgn0039244
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_010694.1
• Gene: PDR15 / 852015
• SGDID: S000002814
• Length: 1529
• Species: Saccharomyces cerevisiae
• Alignment Length: 652
• Identity: 153/652 - (23%)
• Similarity: 264/652 - (40%)
• Gaps: 123/652 - (18%)

  Fly    15 IFHTTEVDGGGCFNG--AGNSALVLKGVNLTVHSGEVMAILGSKGSGKRALLDVISRRAD-GATR 76
            |||..::    |::.  .|....:|..|:..|..|.:.|::|:.|:||..|||.::.|.. |...
Yeast   883 IFHWRDL----CYDVPIKGGQRRILNNVDGWVKPGTLTALMGASGAGKTTLLDCLAERVTMGVIT 943

  Fly    77 GQVLLNGSPLSKALFQQRCGYVTQSCTFVPGLTVAQTLHYT-----PTILSGYLKSSKVRQVLAD 136
            |.:.::|. |....|.:..||..|....:...||.::|.::     |:.:|...|:..|.:|:..
Yeast   944 GNIFVDGR-LRDESFPRSIGYCQQQDLHLKTATVRESLRFSAYLRQPSSVSIEEKNRYVEEVIKI 1007

  Fly   137 LALSQVAHKRV----EYLNISEARRLAIGIQLVRDPVMLL-LDEPTHGLDPLSAYLLISILSNTA 196
            |.:.|.:...|    |.||:.:.:||.||::|...|.:|: |||||.|||..:|:....::...|
Yeast  1008 LEMQQYSDAVVGVAGEGLNVEQRKRLTIGVELAARPKLLVFLDEPTSGLDSQTAWDTCQLMRKLA 1072

  Fly   197 KKTGCGILLSLEKPRSDVFPFLDRALFLCLGG-VVYSG----GTRAMLEYFHGIG-FPCPQLENP 255
            .. |..||.::.:|.:.:....||.|||..|| .||.|    |.:.|::||...| ..||...||
Yeast  1073 TH-GQAILCTIHQPSAILMQQFDRLLFLQKGGQTVYFGDLGEGCKTMIDYFESKGAHKCPPDANP 1136

  Fly   256 LMYYLCL--------STVDR----RSRDRFLESSQQIEALVERFSRETPISDAPLNNMGSGKVPL 308
            ..:.|.:        :|.|.    |:.|.:....::::.:.:             |..|..|.|.
Yeast  1137 AEWMLEVVGAAPGSHATQDYNEVWRNSDEYKAVQEELDWMEK-------------NLPGRSKEPT 1188

  Fly   309 A-YGKPGELKVWVM------------------LYLKLLASTFSCGLVGMKTLFLRLLLLPLALSI 354
            | ..||....::..                  |:.|.:.:.|:...:|.........|..|...:
Yeast  1189 AEEHKPFAASLYYQFKMVTIRLFQQYWRSPDYLWSKFILTIFNQVFIGFTFFKADRSLQGLQNQM 1253

  Fly   355 LWAF-YTDVGDDSHGFFTKNGMILNILGLSYGCGILTTISLFPIWRKKFSQDTPEGLYSGTTLLI 418
            |..| ||              :|.|.:...|....:....|:.      :::.|...:|.....:
Yeast  1254 LSIFMYT--------------VIFNPILQQYLPSFVQQRDLYE------ARERPSRTFSWLAFFL 1298

  Fly   419 AYNSVSIPFSAVSAVIASCVVYPLLLDVKYNNGTVFAYL--LVALWSSFVLAEQLTIAFLLVVKV 481
            :...|.||::.::..||.|:.|..:  ..|.|.:....|  ..||:..|.:|..:.|..:.::.:
Yeast  1299 SQIIVEIPWNILAGTIAYCIYYYAV--GFYANASAAGQLHERGALFWLFSIAFYVYIGSMGLLMI 1361

  Fly   482 PFNAAIAVTY----VLVISIALASGTVRSFKGLQP--WLQDNTKGTHTRYASSLLHSIAFQSRKL 540
            .|| .:|.|.    .|:.::||:...|.:...:.|  |:........|....:|| ::...:..:
Yeast  1362 SFN-EVAETAAHMGTLLFTMALSFCGVMATPKVMPRFWIFMYRVSPLTYMIDALL-ALGVANVDV 1424

  Fly   541 NC--------TPTASVICPKPADFMHERLG------LPDPDETIDVAASCAFAVG---LAAFNML 588
            .|        ||.:...|   .|:|...:.      |.||..| |:.:.||.:..   ||.|:..
Yeast  1425 KCSNYEMVKFTPPSGTTC---GDYMASYIKLAGTGYLSDPSAT-DICSFCAVSTTNAFLATFSSH 1485

  Fly   589 VY 590
            .|
Yeast  1486 YY 1487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	70/231 (30%)
		ABC2_membrane	364..515	CDD:473876	31/158 (20%)
PDR15	NP_010694.1	ABC_trans_N	47..162	CDD:464194
		3a01205	110..1518	CDD:273362	153/652 (23%)