DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11069 and ABCG28

DIOPT Version :9

Sequence 1:	NP_651307.2	Gene:	CG11069 / 42976	FlyBaseID:	FBgn0039244	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_200882.4	Gene:	ABCG28 / 836195	AraportID:	AT5G60740	Length:	1109	Species:	Arabidopsis thaliana

Alignment Length:	594	Identity:	137/594 - (23%)
Similarity:	225/594 - (37%)	Gaps:	147/594 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 ALVLKGVNL--------TVHSGEVMAILGSKGSGKRALLDVISRRADGA-TRGQVLLNGSPLSKA 89
            ::.|||.|.        .:..|.|.|::|..|:||...|..::.:|.|. ..|.:|:||...|..
plant   505 SITLKGKNKHLMRCVTGKLSPGRVSAVMGPSGAGKTTFLTALTGKAPGCIMTGMILVNGKVESIQ 569

  Fly    90 LFQQRCGYVTQSCTFVPGLTVAQTLHYT-----PTILSGYLKSSKVRQVLADLALSQVAHK---R 146
            .:::..|:|.|.......|||.:.|.::     |..|....|...|.:|:..|.|..|...   .
plant   570 SYKKIIGFVPQDDIVHGNLTVEENLWFSARCRLPADLPKPEKVLVVERVIESLGLQHVRDSLVGT 634

  Fly   147 VEYLNIS--EARRLAIGIQLVRDPVMLLLDEPTHGLDPLSAYLLISILSNTAKKTGCGILLSLEK 209
            ||...||  :.:|:.:|:::|.:|.:|:|||||.|||..|:.||:..|...|.: |..|.:.:.:
plant   635 VEKRGISGGQRKRVNVGLEMVMEPSLLILDEPTSGLDSSSSQLLLRALRREALE-GVNICMVVHQ 698

  Fly   210 PRSDVFPFLDRALFLCLGGVV-YSGGTRAMLEYFHGIGFPCPQLENPLMYYLCL-------STVD 266
            |...:|...|..:.|..||:: |.|..:.:.|||..:|...|:..||..||:.:       ||..
plant   699 PSYTLFRMFDDLILLAKGGLICYQGPVKKVEEYFSSLGIVVPERVNPPDYYIDILEGILKPSTSS 763

  Fly   267 RRSRDRF-------------LESSQQIEALVERFSRETPISDAPLNNMGSGKVPLAYGK------ 312
            ..:..:.             ::..:.||.:....|.|        |:...|.   |:|.
plant   764 GVTYKQLPVRWMLHNGYPVPMDMLKSIEGMASSASGE--------NSAHGGS---AHGSVVGDDG 817

  Fly   313 ---PGE----LKVWVMLYLKLLASTFS--------------------CGLVGMKTL--------- 341
               .||    :|..|.:....|.:.||                    .|.:|.:.|
plant   818 TSFAGEFWQDVKANVEIKKDNLQNNFSSSGDLSEREVPGVYQQYRYFLGRLGKQRLREARTLAVD 882

  Fly   342 FLRLLLLPLALSILWAFYTDVGDDSHGFFTKNGMILNILGLSYGCGILTTISLFPIWRKKFSQDT 406
            :|.|||..:.|..|    ..|.|::.|..   |....::.:|..|.| |.:..|.:.:..:.:::
plant   883 YLILLLAGICLGTL----AKVSDETFGAM---GYTYTVIAVSLLCKI-TALRSFSLDKLHYWRES 939

  Fly   407 PEGLYSGTTLLIA-----YNSVSIPFSAVSA---------------VIASCVVYPLLLDVKYNNG 451
            ..|:.|....|..     :|::..|...:|.               |:..|:|| .:..:.|...
plant   940 RAGMSSLAYFLAKDTVDHFNTIVKPLVYLSMFYFFNNPRSTVTDNYVVLICLVY-CVTGIAYTLA 1003

  Fly   452 TVFAYLLVALWSSFVLAEQLTIAFLLVVKVPFNAAIAVTYVLVISI-----------ALASGTVR 505
            .:|......|||           .||.|.:...|.......:|.||           |......:
plant  1004 ILFEPGPAQLWS-----------VLLPVVLTLIATSTNDNKIVDSISELCYTRWALEAFVVSNAQ 1057

  Fly   506 SFKGLQPWL 514
            .:||:  ||
plant  1058 RYKGV--WL 1064

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	65/218 (30%)
		CcmA	31..302	CDD:224054	82/307 (27%)
		ABC2_membrane	364..515	CDD:304374	35/182 (19%)
ABCG28	NP_200882.4	ABCG_EPDR	496..723	CDD:213180	65/218 (30%)
ABCG28	NP_200882.4	3a01204	513..1103	CDD:273361	133/586 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910