DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11069 and ABCG6

DIOPT Version :9

Sequence 1:	NP_651307.2	Gene:	CG11069 / 42976	FlyBaseID:	FBgn0039244	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_196862.1	Gene:	ABCG6 / 831202	AraportID:	AT5G13580	Length:	727	Species:	Arabidopsis thaliana

Alignment Length:	624	Identity:	150/624 - (24%)
Similarity:	261/624 - (41%)	Gaps:	109/624 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KMIGSDYVLEAHNIFHTTEVDGGGCFNGAGNSALVLKGVNLTVHSGEVMAILGSKGSGKRALLDV 66
            :.:.||....:..||             :..:..:|.|:......||::|:||:.||||..|:|.
plant    87 RSVSSDPGAPSEGIF-------------SSKTKTLLNGITGEARDGEILAVLGASGSGKSTLIDA 138

  Fly    67 ISRR-ADGATRGQVLLNGSPLSKALFQQRCGYVTQSCTFVPGLTVAQTLHYT-----PTILSGYL 125
            ::.| |.|:.:|.|.|||..|:..:.:....||.|.....|.|||.:||.:.     |..||...
plant   139 LANRIAKGSLKGNVTLNGEVLNSKMQKAISAYVMQDDLLFPMLTVEETLMFAAEFRLPRSLSKSK 203

  Fly   126 KSSKVRQVLADLALSQVAHKRV---EYLNIS--EARRLAIGIQLVRDPVMLLLDEPTHGLDPLSA 185
            ||.:|:.::..|.|...|:..:   .:..||  |.||::|||.::.||::|.|||||.|||..||
plant   204 KSLRVQALIDQLGLRNAANTVIGDEGHRGISGGERRRVSIGIDIIHDPILLFLDEPTSGLDSTSA 268

  Fly   186 YLLISILSNTAKKTGCGILLSLEKPRSDVFPFLDRALFLCLGGVVYSGGTRAMLEYFHGIGFPCP 250
            ..:|.:|...| ::|..::::|.:|...:...|||.|||..|..|:||....:..:|...|.|.|
plant   269 LSVIKVLKRIA-QSGSMVIMTLHQPSYRLLRLLDRLLFLSRGQTVFSGSPAMLPRFFAEFGHPIP 332

  Fly   251 QLENPLMYYLCL------STVDRRS--------RDRFLESSQQI-----EALVERFSRETPISDA 296
            :.||...:.|.|      |....||        |.|..|...|.     ||:....|:...:|.|
plant   333 EHENRTEFALDLIRELEGSAGGTRSLVEFNKGFRQRKAEPRSQTGLSLKEAISASISKGKLVSGA 397

  Fly   297 PLNNMGSGKVPLA----YGKPGELKVWVMLYLKLLASTFSCGLVGMKTLF-LRLLLLPLALSILW 356
            ......||..|::    :..|    .||  .|.:||............|| :||..:.:...||.
plant   398 TTTTHSSGSSPVSTIPTFANP----FWV--ELAVLAKRSMTNSRRQPELFGIRLGAVLVTGFILA 456

  Fly   357 AFYTDVGDDSHGFFTKNGMILNILGLSYGCGILTTISLFPIWRKK---FSQDTPEGLYSGTTLLI 418
            ..:..:.:...|...:.|.....:..::    .|.....|::.::   |.::|....|..::.::
plant   457 TMFWQLDNSPKGVQERLGCFAFAMSTTF----YTCADALPVFLQERFIFMRETAYNAYRRSSYVL 517

  Fly   419 AYNSVSIPFSAVSAVIASCVVYPLLLDVKYNNGTV-----FAYLLVALW--SSFV-----LAEQL 471
            :::.|::|...:.::..:.:.:   ..|..:.|.:     |..:|.:.|  ||||     :...:
plant   518 SHSLVALPSLIILSLAFAAITF---WGVGLDGGLMGFLFYFLVILASFWAGSSFVTFLSGVVPHV 579

  Fly   472 TIAFLLVV-----------------KVP-------FNAAIAVTYVLVISIALASGTVRSFKGLQP 512
            .:.:.:||                 ::|       :.:.:...|..|:.......|....:|:|
plant   580 MLGYTIVVAILAYFLLFSGFFINRDRIPGYWIWFHYISLVKYPYEAVLLNEFGDPTKCFVRGVQ- 643

  Fly   513 WLQDNT------KGTHTRYASSLLHSIAFQSRKLNCTPT 545
             :.|||      :|...|..:::..|:..:.....|..|
plant   644 -IFDNTPLVAVPQGMKVRLLATMSKSLGMRITSSTCLTT 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	77/228 (34%)
		CcmA	31..302	CDD:224054	97/300 (32%)
		ABC2_membrane	364..515	CDD:304374	26/189 (14%)
ABCG6	NP_196862.1	3a01204	105..726	CDD:273361	146/593 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920