DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11069 and ABCG9

DIOPT Version :9

Sequence 1:	NP_651307.2	Gene:	CG11069 / 42976	FlyBaseID:	FBgn0039244	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_194472.3	Gene:	ABCG9 / 828850	AraportID:	AT4G27420	Length:	638	Species:	Arabidopsis thaliana

Alignment Length:	608	Identity:	150/608 - (24%)
Similarity:	264/608 - (43%)	Gaps:	112/608 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KMIGSDYVLEAHNIFHTTEV-DGGGCF--NGAGNSALVLKGVNLTVHSGEVMAILGSKGSGKRAL 63
            |...:...|:..|:.:|.:: |..|||  |.......:|||:...|..||::|:||..||||.:|
plant    29 KKANNPVTLKFENLVYTVKLKDSQGCFGKNDKTEERTILKGLTGIVKPGEILAMLGPSGSGKTSL 93

  Fly    64 LDVISRR---ADGATRGQVLLNGSPLSKALFQQRCGYVTQSCTFVPGLTVAQTLHYTPTIL--SG 123
            |..:..|   ..|...|.:..|..|||||: ::..|:|||.....|.|||.:||.:|..:.  :.
plant    94 LTALGGRVGEGKGKLTGNISYNNKPLSKAV-KRTTGFVTQDDALYPNLTVTETLVFTALLRLPNS 157

  Fly   124 YLKSSKVRQ---VLADLALSQ-----VAHKRVEYLNISEARRLAIGIQLVRDPVMLLLDEPTHGL 180
            :.|..|::|   |:.:|.|.:     :....:..::..|.:|::||.:::.:|.:|.|||||.||
plant   158 FKKQEKIKQAKAVMTELGLDRCKDTIIGGPFLRGVSGGERKRVSIGQEILINPSLLFLDEPTSGL 222

  Fly   181 DPLSAYLLISILSNTAKKTGCGILLSLEKPRSDVFPFLDRALFLCLGGVVYSG-GTRAMLEYFHG 244
            |..:|..::|||...| :.|..::.::.:|.|.:|...|:.|.|..|..||.| |:.|| :||..
plant   223 DSTTAQRIVSILWELA-RGGRTVVTTIHQPSSRLFYMFDKLLLLSEGNPVYFGLGSNAM-DYFAS 285

  Fly   245 IGF-PCPQLENPLMYYLCLST---VDRRSRDRFLESSQQIEALVERFSRETPISDAPLNNMGSGK 305
            :|: |..:..||..:.|.::.   .|...|...:::     |||..:  :|.:.|:.:|.: .|:
plant   286 VGYSPLVERINPSDFLLDIANGVGSDESQRPEAMKA-----ALVAFY--KTNLLDSVINEV-KGQ 342

  Fly   306 VPLAYGKPGELK------------VWVMLYLKLLAS---------------------TFSCGLVG 337
            ..|. .||.|..            .|...:..||..                     :|.|||:.
plant   343 DDLC-NKPRESSRVATNTYGDWPTTWWQQFCVLLKRGLKQRRHDSFSGMKVAQIFIVSFLCGLLW 406

  Fly   338 MKTLFLRL---LLLPLALSILWAFYTDVGDDSHGFFTKNGMILNILGLSYGCGILTTISLFPIWR 399
            .:|...||   :.|...:|..|||:.                           :...|..||..|
plant   407 WQTKISRLQDQIGLLFFISSFWAFFP---------------------------LFQQIFTFPQER 444

  Fly   400 KKFSQDTPEGLYSGTTLLIAYNSVSIPFSAVSAVIASC--VVYPLLLDVKYNNGTVFAYLLVALW 462
            ....::...|:|..:...::.....:|   :..::.:|  |:...:..:.:|....|..|||.|
plant   445 AMLQKERSSGMYRLSPYFLSRVVGDLP---MELILPTCFLVITYWMAGLNHNLANFFVTLLVLL- 505

  Fly   463 SSFVLAEQLTIAFLLVVKVPFNAAIAVTYVLVISIALASG-TVRSFKGLQPWLQDNTKGTHT--- 523
            ...:::..|.:|...:| :...:|..:..|::::..||.| .|:.......|::..:.|.:|
plant   506 VHVLVSGGLGLALGALV-MDQKSATTLGSVIMLTFLLAGGYYVQHVPVFISWIKYVSIGYYTYKL 569

  Fly   524 ----RYASSLLHSIAFQSRKLNC 542
                :|.::.|:... .:.||.|
plant   570 LILGQYTANELYPCG-DNGKLRC 591

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	76/233 (33%)
		CcmA	31..302	CDD:224054	89/288 (31%)
		ABC2_membrane	364..515	CDD:304374	25/153 (16%)
ABCG9	NP_194472.3	PLN03211	19..632	CDD:215634	150/608 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820