DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11069 and ABCG18

DIOPT Version :9

Sequence 1:	NP_651307.2	Gene:	CG11069 / 42976	FlyBaseID:	FBgn0039244	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_191071.1	Gene:	ABCG18 / 824677	AraportID:	AT3G55110	Length:	708	Species:	Arabidopsis thaliana

Alignment Length:	503	Identity:	133/503 - (26%)
Similarity:	226/503 - (44%)	Gaps:	84/503 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 VLKGVNLTVHSGEVMAILGSKGSGKRALLDVISRR-ADGATRGQVLLNGSP-LSKALFQQRCGYV 98
            :|..:......||::|:||..|:||..|:|.::.| |:.:.:|.|.|||.. |...|.:....||
plant    91 LLDDITGEARDGEILAVLGGSGAGKSTLIDALAGRVAEDSLKGTVTLNGEKVLQSRLLKVISAYV 155

  Fly    99 TQSCTFVPGLTVAQTLHYT-----PTILSGYLKSSKVRQV-----------LADLALSQVAHKRV 147
            .|.....|.|||.:||.:.     |..|.   ||.|:.:|           .||..:....|:.|
plant   156 MQDDLLFPMLTVKETLMFASEFRLPRSLP---KSKKMERVETLIDQLGLRNAADTVIGDEGHRGV 217

  Fly   148 EYLNISEARRLAIGIQLVRDPVMLLLDEPTHGLDPLSAYLLISILSNTAKKTGCGILLSLEKPRS 212
               :..|.||::|||.::.||::|.|||||.|||..:|::::.:|...| ::|..:::|:.:|.:
plant   218 ---SGGERRRVSIGIDIIHDPILLFLDEPTSGLDSTNAFMVVQVLKRIA-QSGSVVIMSIHQPSA 278

  Fly   213 DVFPFLDRALFLCLGGVVYSGGTRAMLEYFHGIGFPCPQLENPLMYYLCL------STVDRRSRD 271
            .:...|||.:.|..|..|::|...::..:|...|.|.|:.||...:.|.:      |:...|...
plant   279 RIIGLLDRLIILSHGKSVFNGSPVSLPSFFSSFGRPIPEKENITEFALDVIRELEGSSEGTRDLV 343

  Fly   272 RFLESSQQ--------------IEALVERFSRETPISDAPLNNMGSGKVPLAYGKPGELKVWVML 322
            .|.|..||              .||:....||...:|.:...|..|.:...:|..|...:.:::.
plant   344 EFNEKWQQNQTARATTQSRVSLKEAIAASVSRGKLVSGSSGANPISMETVSSYANPPLAETFILA 408

  Fly   323 --YLKLLASTFSCGLVGMK--TLFLRLLLLPLALSILWAF-YTDVG-DDSHGFFTKNGMILNILG 381
              |:|....|..  |:||:  |:.:..|||   .::.|.. .|..| .:..|||.        .|
plant   409 KRYIKNWIRTPE--LIGMRIGTVMVTGLLL---ATVYWRLDNTPRGAQERMGFFA--------FG 460

  Fly   382 LS---YGCGILTTISLFPIWRKKFSQDTPEGLYSGTTLLIAYNSVSIP--------FSA------ 429
            :|   |.|.  ..|.:|...|..|.::|....|..::.:|::..||:|        |:|
plant   461 MSTMFYCCA--DNIPVFIQERYIFLRETTHNAYRTSSYVISHALVSLPQLLALSIAFAATTFWTV 523

  Fly   430 -VSAVIASCVVYPLLLDVKYNNGTVFAYLLVALWSSFVLAEQLTIAFL 476
             :|..:.|...|.|::...:.:|:.....:..|..:.:::..:|||:|
plant   524 GLSGGLESFFYYCLIIYAAFWSGSSIVTFISGLIPNVMMSYMVTIAYL 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	68/214 (32%)
		CcmA	31..302	CDD:224054	88/303 (29%)
		ABC2_membrane	364..515	CDD:304374	29/131 (22%)
ABCG18	NP_191071.1	3a01204	57..707	CDD:273361	133/503 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920