DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11069 and ABCG20

DIOPT Version :9

Sequence 1:	NP_651307.2	Gene:	CG11069 / 42976	FlyBaseID:	FBgn0039244	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_190919.1	Gene:	ABCG20 / 824519	AraportID:	AT3G53510	Length:	739	Species:	Arabidopsis thaliana

Alignment Length:	562	Identity:	144/562 - (25%)
Similarity:	245/562 - (43%)	Gaps:	107/562 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SDYVLEAHNIFHTTEVD---------GGGCFNGAG---NSALVLKGVNLTVHSGEVMAILGSKGS 58
            |.:||...::.::.::.         |...|:|..   |:.::|.|::.....||:||:||:.||
plant    84 SPFVLSFKDLTYSVKIKKKFKPFPCCGNSPFDGNDMEMNTKVLLNGISGEAREGEMMAVLGASGS 148

  Fly    59 GKRALLDVISRR-ADGATRGQVLLNGSPLSKALFQQRCGYVTQSCTFVPGLTVAQTLHYT----- 117
            ||..|:|.::.| :..:.||.:.|||..|..:|.:....||.|.....|.|||.:||.::
plant   149 GKSTLIDALANRISKESLRGDITLNGEVLESSLHKVISAYVMQDDLLFPMLTVEETLMFSAEFRL 213

  Fly   118 PTILSGYLKSSKVRQVLADLALSQVA--------HKRVEYLNISEARRLAIGIQLVRDPVMLLLD 174
            |:.||...|.::|:.::..|.|...|        |:.|   :..|.||::||..::.||::|.||
plant   214 PSSLSKKKKKARVQALIDQLGLRNAAKTVIGDEGHRGV---SGGERRRVSIGTDIIHDPIILFLD 275

  Fly   175 EPTHGLDPLSAYLLISILSNTAKKTGCGILLSLEKPRSDVFPFLDRALFLCLGGVVYSGGTRAML 239
            |||.|||..|||:::.:|...| ::|..:::|:.:|...:...||:.:||..|..||||....:.
plant   276 EPTSGLDSTSAYMVVKVLQRIA-QSGSIVIMSIHQPSYRILGLLDKLIFLSRGNTVYSGSPTHLP 339

  Fly   240 EYFHGIGFPCPQLENPLMYYLCL------------STVDRRSRDRFLESSQQIEALVERFSRETP 292
            ::|...|.|.|:.||...:.|.|            |.|:...:.|..::|.|     .|.:....
plant   340 QFFSEFGHPIPENENKPEFALDLIRELEDSPEGTKSLVEFHKQWRAKQTSSQ-----SRRNTNVS 399

  Fly   293 ISDAPLNNMGSGKVP----------LAYGKPGELKVWVMLYLKLLASTFSCGLVGMKTLFLRLLL 347
            :.||...::..||:.          ..:..|...::.|:....:|.|.....|.|     :||..
plant   400 LKDAISASISRGKLVSGATNLRSSFQTFANPFWTEMLVIGKRSILNSRRQPELFG-----IRLGA 459

  Fly   348 LPLALSILWAFYTDVGDDSHGFFTKNGMILNILGLS-YGCGILTTISLFPIWRKKFSQDTPEGLY 411
            :.:...||...:..:.:...|...:.|.....:..: |.|.  ..|.:|...|..|.::|....|
plant   460 VLVTGMILATIFWKLDNSPRGIQERLGFFAFAMSTTFYTCA--EAIPVFLQERYIFMRETAYNAY 522

  Fly   412 SGTTLLIAYNSVSIP-------------FSAVSAVIASCVVYPLLLDVKYNNGTVFAY--LLVAL 461
            ..::.::|:..:|||             ||||.....|             .|.:|.:  :|.|.
plant   523 RRSSYVLAHTIISIPALIILSAAFAASTFSAVGLAGGS-------------EGFLFFFFTILTAF 574

  Fly   462 W--SSFV-----LAEQLTIAFLLVVKVPFNAAIAVTYVLVIS 496
            |  ||||     :...:.|.|.:||.:       :.|.|:.|
plant   575 WAGSSFVTFLSGVVSHVMIGFTVVVAI-------LAYFLLFS 609

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	76/243 (31%)
		CcmA	31..302	CDD:224054	91/299 (30%)
		ABC2_membrane	364..515	CDD:304374	35/156 (22%)
ABCG20	NP_190919.1	P-loop_NTPase	119..333	CDD:304359	73/217 (34%)
		3a01204	120..738	CDD:273361	138/526 (26%)
		ABC2_membrane	438..641	CDD:279410	43/199 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920