DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11069 and ABCG5

DIOPT Version :9

Sequence 1:	NP_651307.2	Gene:	CG11069 / 42976	FlyBaseID:	FBgn0039244	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_178984.1	Gene:	ABCG5 / 815846	AraportID:	AT2G13610	Length:	649	Species:	Arabidopsis thaliana

Alignment Length:	506	Identity:	132/506 - (26%)
Similarity:	230/506 - (45%)	Gaps:	58/506 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 VLKGVNLTVHSGEVMAILGSKGSGKRALLDVISRRADGATRGQVLLNGSPLSKALFQQRCGYVTQ 100
            |||||.......|::||:|..|:||.:||::::.|....| |.|.:|..|:.:|.|::..|||||
plant    62 VLKGVTCRAKPWEILAIVGPSGAGKSSLLEILAARLIPQT-GSVYVNKRPVDRANFKKISGYVTQ 125

  Fly   101 SCTFVPGLTVAQTLHYTPTI---LSGYLKSSKVRQVLADLALSQVAHKR-----VEYLNISEARR 157
            ..|..|.|||.:||.::..:   |......|:|:.::.:|.|..||..|     |..::..|.||
plant   126 KDTLFPLLTVEETLLFSAKLRLKLPADELRSRVKSLVHELGLEAVATARVGDDSVRGISGGERRR 190

  Fly   158 LAIGIQLVRDPVMLLLDEPTHGLDPLSAYLLISILSNTAKKTGCGILLSLEKPRSDVFPFLDRAL 222
            ::||::::.||.:|:|||||.|||..||.|:|.:|.:.|:..|..|:|::.:|...:....:..|
plant   191 VSIGVEVIHDPKVLILDEPTSGLDSTSALLIIDMLKHMAETRGRTIILTIHQPGFRIVKQFNSVL 255

  Fly   223 FLCLGGVVYSGGTRAMLEYFHGIGFPCPQLENPLMYYLCLSTVDRRSRDRFLESSQQIEALVERF 287
            .|..|..:..|....:..|....|...|..|| ::.:...|......:.|..||.:....|..:.
plant   256 LLANGSTLKQGSVDQLGVYLRSNGLHPPLHEN-IVEFAIESIESITKQQRLQESRRAAHVLTPQT 319

  Fly   288 SRETPISDAPLNNMGSGKVPL-------AYGKPGELKVWV----------MLYLKLLASTFSCGL 335
            :.:...|:.......|||..|       .....|.:.:..          :....:|...||..:
plant   320 TLQEKRSEDSQGESKSGKFTLQQLFQQTRVADVGTMNIATEFTRDFANSRLEETMILTHRFSKNI 384

  Fly   336 VGMKTLF----LRLLLLPLALSILWAFYTDVGDDSHGFFTKNGMILNILGLSYGCGILT-TISLF 395
            ...|.||    :::|...:.|.::   :.::.||..|...:.|:...||..     :|| ||...
plant   385 FRTKELFACRTVQMLGSGIVLGLI---FHNLKDDLKGARERVGLFAFILTF-----LLTSTIEAL 441

  Fly   396 PIW---RKKFSQDTPEGLYSGTTLLIAYNSVSIPFSAVSAVIASCVVYPLL-LDVKYNNGTVFAY 456
            ||:   |:...::|..|.|..::..:|...|.:||..:.|::.|..||.|: |:..:   ..|.:
plant   442 PIFLQEREILMKETSSGSYRVSSYAVANGLVYLPFLLILAILFSTPVYWLVGLNPSF---MAFLH 503

  Fly   457 LLVALWSSFVLAEQLTIAFLLVVKVPFNAAIAVTYVLVISIALASGTVRSF 507
            ..:.:|.....|..:.:.|         :|:...:  ::..::.||.:.||
plant   504 FSLLIWLILYTANSVVVCF---------SALVPNF--IVGNSVISGVMGSF 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	72/204 (35%)
		CcmA	31..302	CDD:224054	84/273 (31%)
		ABC2_membrane	364..515	CDD:304374	35/149 (23%)
ABCG5	NP_178984.1	3a01204	37..638	CDD:273361	132/506 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880