DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11069 and abcg2d

DIOPT Version :9

Sequence 1:	NP_651307.2	Gene:	CG11069 / 42976	FlyBaseID:	FBgn0039244	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	XP_009292498.3	Gene:	abcg2d / 735310	ZFINID:	ZDB-GENE-050517-38	Length:	658	Species:	Danio rerio

Alignment Length:	544	Identity:	145/544 - (26%)
Similarity:	249/544 - (45%)	Gaps:	61/544 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 HNIFHTTEVDGGGCFNGAGNSALVLKGVNLTVHSGEVMAILGSKGSGKRALLDVISRRADGA-TR 76
            |:|.:..|...|...........:|..:|..:..| :.||||..||||.:.|||::.|.|.| ..
Zfish    43 HSIRYRVEQKTGPVCRRTTVQKEILLDLNGIMRPG-LNAILGPTGSGKSSFLDVLAGRKDPAGLS 106

  Fly    77 GQVLLNGSPLSKALFQQRCGYVTQSCTFVPGLTVAQTLHYTPTI-LSGYL----KSSKVRQVLAD 136
            |:||:||: |..|.|:...|||.|....:..|||.:.|.::..: ||.::    |.::|..::::
Zfish   107 GEVLVNGA-LQPANFKCLSGYVVQDDIVMGTLTVRENLSFSAALRLSSHVSPREKEARVNHLISE 170

  Fly   137 LALSQVAHKRV-----EYLNISEARRLAIGIQLVRDPVMLLLDEPTHGLDPLSAYLLISILSNTA 196
            |.|::||..:|     ..::..|.:|.:||::|:.||.:|.|||||.|||..:|:.::.:|...|
Zfish   171 LGLNKVADSKVGTQIIRGISGGERKRTSIGMELIIDPSVLFLDEPTTGLDASTAHSVLLLLKRMA 235

  Fly   197 KKTGCGILLSLEKPRSDVFPFLDRALFLCLGGVVYSGGTRAMLEYFHGIGFPCPQLENPLMYYL- 260
            .: |..|::|:.:||..::...|....|..|..||.|..:..|:||..||:.|....||..::|
Zfish   236 GQ-GRTIIMSIHQPRFSIYRLFDSLTLLANGKQVYHGPAQDALDYFSNIGYACEAHNNPADFFLD 299

  Fly   261 -----------------C-LSTVDRRS-RDRFLE---SSQQIEALVERFSRETPISDAPLNNMGS 303
                             | :|.|.|:| .|:.:|   |.....|:...........|:..:::.:
Zfish   300 VINGSSVTKIQNNGDAECDVSAVSRQSVEDQLMEKYRSCSFARAVRAELDHIIQTKDSSSSSVAA 364

  Fly   304 GKVPLAYGKP--GELKVWVMLYLKLLASTFSCGLVGMKTLFLRLLLLPLALSILWAFYTDVGDDS 366
            ....:.|...  .:|: ||      |..||...::..:|...:|.:..|..:|:.|.:..|.||.
Zfish   365 ECHSITYSSSFCQQLR-WV------LWRTFWNLMLNPQTSVAQLAVTTLMAAIVGAIFYGVKDDQ 422

  Fly   367 HGFFTKNGMILNILGLSYGC-GILTTISLFPIWRKKFSQDTPEGLYSGTTLLIA-YNSVSIPFSA 429
            .|...:.|::..|  .:..| ..|:...||...||.|..:...|.|..:...:: ..|..|....
Zfish   423 SGIQNRFGVLFFI--TTNQCFSTLSAAELFITERKLFIHEYTSGYYRVSVFFLSKILSDIITQRT 485

  Fly   430 VSAVIASCVVYPLLLDVKYNNGTVFAYLLVALWSSFVLAEQLTIAFLLVVKVPFNAAIAVTYVLV 494
            :.:|:.||||| .::.:|......|.::|.      |:....|.|.:.:......:.:||..:|:
Zfish   486 IPSVLFSCVVY-FMIGLKPTASAFFIFMLT------VILVSCTAAAMAMAISADQSVVAVANILM 543

  Fly   495 ----ISIALASGTVRSFKGLQPWL 514
                |.:.:.||.:.:.|.:..||
Zfish   544 TVSFIFMMIFSGLLVNLKSIMDWL 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	74/228 (32%)
		CcmA	31..302	CDD:224054	91/304 (30%)
		ABC2_membrane	364..515	CDD:304374	37/157 (24%)
abcg2d	XP_009292498.3	PRK10535	56..658	CDD:333000	141/531 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920