Protein Alignment CG11069 and abcg2

DIOPT Version :9

• Sequence 1: NP_651307.2
• Gene: CG11069 / 42976
• FlyBaseID: FBgn0039244
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_012819987.2
• Gene: abcg2 / 734088
• XenbaseID: XB-GENE-991895
• Length: 682
• Species: Xenopus tropicalis
• Alignment Length: 667
• Identity: 161/667 - (24%)
• Similarity: 271/667 - (40%)
• Gaps: 124/667 - (18%)

  Fly     6 SDYVLEAHNIFHTTEVDGGGCFNGAGNSALVLKGVNLTVHSGEVMAILGSKGSGKRALLDVISRR 70
            |..||..:||.:..:|..|..........::|..||..:..| :.||||..||||.:||||::.|
 Frog    52 SGAVLSFYNINYKVKVKSGLICCRKVTERVILNDVNGIMRPG-LNAILGPTGSGKSSLLDVLAAR 115

  Fly    71 AD-GATRGQVLLNGSPLSKALFQQRCGYVTQSCTFVPGLTVAQTLHYT-----PTILSGYLKSSK 129
            .| ....||||::|.| ..:.|:...|||.|....:..|::.:.|.::     |..:....|..:
 Frog   116 KDPNGLSGQVLVDGEP-QPSNFKCLSGYVVQDDVVMGTLSIRENLQFSAALRLPRSVKQKEKDER 179

  Fly   130 VRQVLADLALSQVAHKRV-----EYLNISEARRLAIGIQLVRDPVMLLLDEPTHGLDPLSAYLLI 189
            :.||:.:|.|::||..:|     ..::..|.:|..||::|:.||.:|.|||||.|||..:|..::
 Frog   180 INQVIKELGLTKVADSKVGTQFIRGVSGGERKRTNIGMELITDPGILFLDEPTTGLDASTANAVL 244

  Fly   190 SILSNTAKKTGCGILLSLEKPRSDVFPFLDRALFLCLGGVVYSGGTRAMLEYFHGIGFPCPQLEN 254
            .:|...::: |..|:.|:.:||..:|...|....|..|.:::.|.:|..|:||.|:|:.|....|
 Frog   245 LLLKRMSRQ-GKTIIFSIHQPRYSIFRLFDSLTLLAGGRLLFHGPSRDALDYFTGLGYECESHNN 308

  Fly   255 PLMYYLCLSTVD------RRSRDRFLESSQQ----------IEALVERFSR-----ETPISDAPL 298
            |..::|.:...|      .:..|..||:.|:          :|.|.|:|..     ||   .|.|
 Frog   309 PADFFLDIINGDSTAVALNKLEDVELENEQKEVNDNGSKTVVENLSEQFCTTSYYLET---KAEL 370

  Fly   299 NNMGSGKVPLAYGKPGELKVWVMLYLKLLASTFSCGLVGMKTLFLR------------------- 344
            ..|..|                    |.:.|.|....:...|.||.
 Frog   371 EKMSLG--------------------KKIKSNFFARQITYNTSFLHQLKWVCKRSFKNLWRNPQA 415

  Fly   345 -----LLLLPLALSILWAFYTDVGDDSHGFFTKNGMILNILGLSYGC-GILTTISLFPIWRKKFS 403
                 ::.|.||| |:.|.:..|.:|..|...:.|.:..:  .:..| ..::.|.||.:.:|.|.
 Frog   416 SIAQVMVTLVLAL-IVGAIFFGVKEDVSGIQNRVGSLFFV--TTNQCFSSVSAIELFIVEKKIFI 477

  Fly   404 QDTPEGLYSGTTLLIAYNSVS-----IPFSAVSAVIASCVVYPLLLDVKYNNGTVFAYLLVALWS 463
            .:...|.|.    |.||....     :|...:.::|.:.|:| .::..|...|..|..:...:..
 Frog   478 HEYISGYYR----LSAYFFAKLFTDLLPMRTLPSIIFTSVIY-FMIGFKATAGAFFTMMFTLMMI 537

  Fly   464 SFVLAEQ-LTIAFLLVVKVPFNAAIAVTYVLVISIALASGTVRSFKGLQPWLQDNTKGTHTRYAS 527
            ::..|.. |.:|....|....|..:.:.:|.:|   :.||.:.:...:..|:......:..||..
 Frog   538 AYTAASMALAVAAGQDVVAVANLLMTICFVFMI---IFSGLLVNLTSVMDWISWLKYFSIPRYGL 599

  Fly   528 SLLHSIAFQS----RKLNCTPTASVICPKPADFMHERLGLPDPDETIDV---------------A 573
            :.|....|.:    ..||.|...:..|...:.|     |....:|.:.|               |
 Frog   600 TALQINEFTNLNFCNGLNTTIQGNPNCTGSSPF-----GTCTGEEYLTVQGIDFSTWGLWQNHLA 659

  Fly   574 ASCAFAVGLAAFNMLVY 590
            .:|..|:.|....:.:|
 Frog   660 LACMIAIFLTIAYLKLY 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	70/228 (31%)
		CcmA	31..302	CDD:224054	91/302 (30%)
		ABC2_membrane	364..515	CDD:304374	31/157 (20%)
abcg2	XP_012819987.2	3a01204	73..675	CDD:273361	153/643 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010