Protein Alignment CG11069 and abcg2b

DIOPT Version :10

• Sequence 1: NP_651307.2
• Gene: CG11069 / 42976
• FlyBaseID: FBgn0039244
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_001034155.1
• Gene: abcg2b / 570453
• ZFINID: ZDB-GENE-050517-36
• Length: 618
• Species: Danio rerio
• Alignment Length: 563
• Identity: 140/563 - (24%)
• Similarity: 237/563 - (42%)
• Gaps: 88/563 - (15%)

  Fly     9 VLEAHNIFHTTEVDGGGCFNGAGNSALVLKGVNLTVHSGEVMAILGSKGSGKRALLDVISRRAD- 72
            :|...||.:......|.|...|.... :||.|:..:.:| :.||:|:.||||.:||||::.|.|
Zfish    27 ILTYQNIHYCIRESRGLCCKKAPERD-ILKNVSGIMKTG-LNAIMGATGSGKTSLLDVMAGRKDP 89

  Fly    73 -GATRGQVLLNGSPLSKALFQQRCGYVTQSCTFVPGLTVAQTLHYTPTILSGYL----------- 125
             |...||||::...::..| :....||.|....:..|||.:.|     :.||.|
Zfish    90 RGLRSGQVLVDNKLVTSDL-RLMSAYVVQDDVLMGTLTVRENL-----LFSGNLRLPREQFSSAD 148

  Fly   126 KSSKVRQVLADLALSQVAHKRV--EYL-NIS--EARRLAIGIQLVRDPVMLLLDEPTHGLDPLSA 185
            |..||..::.:|.|...|..::  |:: .:|  |.:|.:||::|:..|.:|.|||||.|||..:|
Zfish   149 KKKKVESIIEELGLEDCADTKIGTEFIRGVSGGERKRCSIGMELITSPTLLFLDEPTTGLDSNTA 213

  Fly   186 YLLISILSNTAKKTGCGILLSLEKPRSDVFPFLDRALFLCLGGVVYSGGTRAMLEYFHGIGFPCP 250
            ..:|::| :...:.|..|:.|:.:||..:|...|....:..|..||:|.....::||..:|:...
Zfish   214 NSIIALL-HRLSRGGRTIIFSIHQPRYSIFRLFDYLTLMHKGETVYAGPAGKAIDYFQSLGYERD 277

  Fly   251 QLENPLMYYL-------CLSTVDRRSRDRFLESSQQIEALVERFSRETPISDAPLNNMGSGKVP- 307
            ...||..::|       ..|....:|.......||...|:.|.....|..||: |:...| |.|
Zfish   278 AFNNPADFFLDITNGETATSMPTEKSLAELYRESQFCTAVDEELKCITGPSDS-LSEAKS-KAPS 340

  Fly   308 ----LAYGKPGELKV--WVMLYLKLLASTFSCGLVGMKTLF---LRLLLLPLALSILWAFYTDVG 363
                .:|    :|||  |......:.....|...:.|..||   :.|:...:.|::..|....:|
Zfish   341 YVTSFSY----QLKVVCWRTGLNVVRNPQTSYAQIAMNILFALLIGLVYYQMPLTLPEALQNRIG 401

  Fly   364 DDSHGFFTKNGMILNILGLSYGCGILTTISLFPIWRKKFSQDTPEGLYSGTTL------------ 416
                .||.   :|:|::     .|.|:.:.||...|..|..:...|.|..:..
Zfish   402 ----AFFF---LIINMV-----FGNLSAVELFINERAIFVHENSGGYYRTSVYFLSKVFVDLLPN 454

  Fly   417 ----LIAYNSVSIPFSAVSAVIASCVVYPLLLDVKYNNGTVFAYLLVALWSSFVLAEQLTI---- 473
                ::.::|:|.....::....|.:.:.|.:.:....|...|:|:.|..|:|.:|..|.:
Zfish   455 RIVPILIFSSISYYMMGLNPAFTSFLCFALTVSLVSLAGVSLAFLVSASVSTFAMANILVVLPFV 519

  Fly   474 ------AFLLVVKVPFNAAIAVTYVLVISIALASGTVRSFKGL 510
                  .||:.:....|....:.:..:....|.:.|:...|||
Zfish   520 FMMVFGGFLVNLNSMLNWLSWLKWTSIFKYGLDAVTINEMKGL 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	73/235 (31%)
		ABC2_membrane	364..515	CDD:473876	32/173 (18%)
abcg2b	NP_001034155.1	3a01204	41..616	CDD:273361	137/549 (25%)