Protein Alignment CG11069 and abcg4a

DIOPT Version :10

• Sequence 1: NP_651307.2
• Gene: CG11069 / 42976
• FlyBaseID: FBgn0039244
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_687685.2
• Gene: abcg4a / 564842
• ZFINID: ZDB-GENE-050517-39
• Length: 641
• Species: Danio rerio
• Alignment Length: 650
• Identity: 145/650 - (22%)
• Similarity: 264/650 - (40%)
• Gaps: 116/650 - (17%)

  Fly     7 DYVLEAHNIFHT----------TE----VDGGGCFNGAGNSALVLKGVNLTVHSGEVMAILGSKG 57
            :::.||....|.          ||    :..|.|:...|..|| ||.::....|.|::.|:|..|
Zfish    36 NHITEAQRFSHLPRRSTVDLEFTELSYTIREGPCWRRRGFKAL-LKCLSGKFCSRELIGIMGPSG 99

  Fly    58 SGKRALLDVISRRADGATRGQVLLNGSPLSKALFQQRCGYVTQSCTFVPGLTVAQTLHYTPTILS 122
            :||..|:::::...:...:||:|:||.|.....|::...|:.|....:|.||..:.:     ::|
Zfish   100 AGKSTLMNILAGYRETGMKGQILVNGRPRDLRTFRKMSCYIMQDDMLLPHLTTREAM-----MVS 159

  Fly   123 GYLKSSK--------VRQVLADLALSQVAHKRVEYLNISEARRLAIGIQLVRDPVMLLLDEPTHG 179
            ..||.::        |.::|..|.|.:.|..|...|:..:.:||||.::||.:|.::..||||.|
Zfish   160 ANLKLNENMEVKKELVNEILTALGLQECAQTRTISLSGGQCKRLAIALELVNNPPVMFFDEPTSG 224

  Fly   180 LDPLSAYLLISILSNTAKKTGCGILLSLEKPRSDVFPFLDRALFLCLGGVVYSGGTRAMLEYFHG 244
            ||..|.:.::|::.:.| :.|..|:.::.:|.:.:|...|:...|..|..:|.|....::.|...
Zfish   225 LDSASCFQVVSLMKSLA-QGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIYKGTVPYLIPYLKN 288

  Fly   245 IGFPCPQLENPLMYY----------------------LCLSTVDRRSRDRFLESSQQIEALVERF 287
            :|..||...||..:.                      ||.....:.|.|
Zfish   289 LGLHCPTYHNPADFIIEVASGEYGDLNPVLFEAVQGGLCSDDSKKNSSD---------------- 337

  Fly   288 SRETPISDAPLNNMGSGKVPLAYGKPGELKVWVMLYLK---LLASTFSCGLVGMKTLFLRL---- 345
             :..|.:..|..         .|...|        |::   ...||.:...:..|..|:.:
Zfish   338 -KNDPTTSCPSQ---------CYPDSG--------YIEKHTFATSTLTQFCILFKRTFITICRDV 384

  Fly   346 ------LLLPLALSIL-WAFYTDVGDDSHGFFTKNG-MILNILGLSYGCGILTTISLFPIWRKKF 402
                  ::..|.:.:| ...|.::|:|:...|...| :..::|.|.: ..::.|:..||:....|
Zfish   385 VLTHLRVMSHLCIGVLIGLLYLNIGNDASKVFNNTGFLFFSMLFLMF-AALMPTVLTFPLEMGVF 448

  Fly   403 SQDTPEGLYSGTTLLIAYNSVSIPFSAVSAVIASCVVYPLLLDVKYNNGTVFAYLL-VALWSSFV 466
            .::.....||.....:|.....|||..:..::...:|| .:.:.....|   .||| :||.:|..
Zfish   449 IREHLNYWYSLKAYYLAKTMADIPFQVICPIMYCSIVY-WMTEQPPEAG---RYLLFMALSTSTA 509

  Fly   467 LAEQLTIAFLLVVKVPFNAAIAVTYVLVISIALASGTVRSFKGLQPWLQDNTKGTHTRYA-SSLL 530
            |..|.....:.........|..|..|..|.:.|.||...:|..:..:||.::..::.||. ..::
Zfish   510 LVAQSLGLLIGAASTSLQVATFVGPVSAIPVLLFSGFFVNFDTIPKYLQWSSYVSYVRYGFEGVI 574

  Fly   531 HSIAFQSR-KLNCTPTASVIC--PKPADFMHERLGLPDPDETIDVAASCAF--AVGLAAFNMLVY 590
            .||...:| :|.|   ..::|  .||.:.: :.|.:.|....:|......|  .:.||.:.:|.|
Zfish   575 LSIYGMNRSELEC---PGIVCKFQKPEEVL-QLLDVEDAKLYVDFMVLGVFFLVLRLATYFVLRY 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	65/239 (27%)
		ABC2_membrane	364..515	CDD:473876	34/152 (22%)
abcg4a	XP_687685.2	3a01204	38..641	CDD:273361	144/647 (22%)