DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11069 and CG31121

DIOPT Version :9

Sequence 1:	NP_651307.2	Gene:	CG11069 / 42976	FlyBaseID:	FBgn0039244	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_733058.1	Gene:	CG31121 / 42975	FlyBaseID:	FBgn0051121	Length:	911	Species:	Drosophila melanogaster

Alignment Length:	691	Identity:	157/691 - (22%)
Similarity:	276/691 - (39%)	Gaps:	169/691 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 TEVDGGG------------------CFNGAGNS---------ALV--------------LKGVNL 42
            ::|||||                  ..||.|::         .|:              |:||::
  Fly   260 SQVDGGGGGMGYDYNEARLYGSSRQYGNGNGHNPGSRKQSGMGLIYPNIQVHCLDVNPCLRGVSM 324

  Fly    43 TVHSGEVMAILGSKGSGKRALLDVISRRADGATR---GQVLLNGSPLSKALFQQRCGYV--TQSC 102
            ...:|::.||:.:......||.:.::    |.|.   |::|:||..:|:...::.|.||  .:..
  Fly   325 QAKAGDLFAIMATSQREGSALAECLA----GLTERLGGEILINGQQVSRRGLRELCSYVPALEVS 385

  Fly   103 TFVPGLTVAQTLHYTPTILSGYLKSSKVRQ----VLADLALSQVAHKRVEYLNISEARRLAIGIQ 163
            :..|.::|..||:: ...|.|.:..|.:.:    ::.||.|:.|....|..|..||.:||::..|
  Fly   386 SLDPRMSVQCTLNF-HAALRGPIDRSDLEERMDVLIEDLGLNTVRASNVSTLTHSEKQRLSVACQ 449

  Fly   164 LVRDPVMLLLDEPTHGLDPLSAYLLISILSNTAKKTGCG----ILLSLEKPRSDVFPFLDRALFL 224
            |:....:|:||:.|..:|....:.|:..|     :..|.    ::::|:.|..::.......|.|
  Fly   450 LLAQSSLLILDQVTSNMDIFDTFFLVEYL-----RQWCSGGRIVIMTLQPPTFEILSMCSGVLLL 509

  Fly   225 CLGGVVYSGGTRAMLEYFHGIGFPCPQLENPLMYYLCLSTVDRRSRDRFLESSQQIEALV---ER 286
            ..|..|:||....:..:...:|:|||..:||..|||.|.|:|..|....||||.:||:|.   ::
  Fly   510 SGGRTVFSGSRADLPRHMGELGYPCPPFKNPADYYLDLVTLDDLSAAAMLESSARIESLANAWDQ 574

  Fly   287 FSRETPISDAPLN----NMGSG---------KVPLAYGKPGELKVWVMLYLKLLASTFSCGLVGM 338
            .:.|.|::..|.:    .|.:|         |....|.:||.|..|:.   ||:|:......:|
  Fly   575 INSEPPLAAPPASLPNFTMKAGFFGQISALIKRFAGYKQPGSLLTWIS---KLIAAAVLSLFIG- 635

  Fly   339 KTLFLRLLLLPLALSILWAFYTDV--GDDSHGFFTKNGMILNILGLSYGCGILTTISLFPIWRKK 401
                          .|.|    ||  .|....:..:.|....::.|.|...::.||......|:.
  Fly   636 --------------CIFW----DVPASDPQLSYHDRLGYHHCVMVLVYWPLVMLTIRDTQEDRRH 682

  Fly   402 FSQDTPEGLYSGTTLLIAYNSVSIPFSAVSAVIASCVVYPLLLDV-------KYNNGT---VFAY 456
            ..:|...|||:.:..:|..:.:.: |.::      |:....||..       .|:|.:   ::.|
  Fly   683 AERDIRLGLYTRSLYIIVQSLLGL-FPSL------CIWLAYLLPAHSMAGLYTYSNSSDTGIYLY 740

  Fly   457 L-LVALWSSFVLAEQLTIAFLLVVKVPFNAAIAVTYVLVISIALASGTV------------RSFK 508
            : .:.|:.:.:....|..|.||..||   :|..|..::.:::|...|.:            ..|.
  Fly   741 MGYMLLYLTLIQTLALFCAHLLPCKV---SASIVNGLISLAVAAVGGYLVHPQNLAQFWSWLQFV 802

  Fly   509 GLQPWL-----QDNTKGTHTRYASSLLHSIAFQSRKLNCTPTASVI----CPKP------ADF-M 557
            ..:.||     ||...      |.:|.:|...|..:........:|    ||.|      .|| :
  Fly   803 SPERWLLPVLVQDEYS------AETLSNSAGLQLCRNKQVQHQEIIVQQPCPPPNGTQVLVDFEL 861

  Fly   558 HERLGLPDPDETIDVAASCAFAVGLAAFNMLVYLFPMPRCV 598
            ..:..:.||..|.|...|.|..:|    ::||:      ||
  Fly   862 LPQQHVLDPTPTYDQTTSVALVLG----SVLVF------CV 892

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	60/267 (22%)
		CcmA	31..302	CDD:224054	78/313 (25%)
		ABC2_membrane	364..515	CDD:304374	33/178 (19%)
CG31121	NP_733058.1	P-loop_NTPase	319..518	CDD:304359	51/208 (25%)
		cbiO	319..491	CDD:130234	45/181 (25%)
		ABC2_membrane	621..809	CDD:279410	40/219 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438909
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850