DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11069 and CG9664

DIOPT Version :9

Sequence 1:	NP_651307.2	Gene:	CG11069 / 42976	FlyBaseID:	FBgn0039244	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_722889.1	Gene:	CG9664 / 33540	FlyBaseID:	FBgn0031515	Length:	609	Species:	Drosophila melanogaster

Alignment Length:	564	Identity:	137/564 - (24%)
Similarity:	230/564 - (40%)	Gaps:	91/564 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 SGEVMAILGSKGSGKRALLDVISR-RADGATRGQVLLNGSPLSKALFQQRCGYVTQSCTFVPGLT 109
            ||.:.||||..|:||..||:.::. :..|.| ||.||||.|.....|::...|:.|:...:..||
  Fly    52 SGRLTAILGPSGAGKSTLLNALAGFKLQGVT-GQFLLNGRPRDIMSFRKMSAYIAQNFVMLNLLT 115

  Fly   110 VAQTLHYT-----PTILSGYLKSSKVRQVLADLALSQVAHKRVEYLNISEARRLAIGIQLVRDPV 169
            |.:||..:     |:..:...|...:..::..|.|.......|:.|:..|.:||:|||:||.:|.
  Fly   116 VEETLRVSTDLKMPSSTAAQEKQKIIDDIIDILQLQSCRRTLVKNLSGGEHKRLSIGIELVTNPP 180

  Fly   170 MLLLDEPTHGLDPLSAYLLISILSNTAKKTGCGILLSLEKPRSDVFPFLDRALFLCLGGVVYSGG 234
            ::..||||.|||.:.:|.:|..|...| ..|..::..:.:|.|.:|...|..|.|..|.|:|:|.
  Fly   181 IMFFDEPTSGLDCVGSYQVICHLQRLA-HDGRIVVCVVHQPGSRLFQLFDDVLVLAHGEVLYAGE 244

  Fly   235 TRAMLEYFHGIGFPCPQLENPLMYYL--C--LSTVDR----RSRDRFLES--SQQIEALVERFSR 289
            .|.||..|...|..|||..||..:.|  |  .||.:|    .::::.:.|  |..::..|:   .
  Fly   245 QREMLPTFAQSGHICPQYYNPADFALEVCSQSSTTERCESLITQNKMMHSTASNVVKLQVD---E 306

  Fly   290 ETPISDA-----PLNNMGSGKVPLAYGKPGELKVWVMLYLKLLASTFSCGLVGMKTLFLRLLLLP 349
            ||.:.|.     .|::: .||..:.:..  :|.|.:..:|:.::.       .|..:.:||::..
  Fly   307 ETALIDVHKDALDLSHL-RGKEQVGFWT--QLSVLLRRHLRSMSR-------DMFAVQMRLVMHV 361

  Fly   350 LALSILWAFYTDVGDDSHGFFTKNGMILNILGLSYGCGILTTI-------------------SLF 395
            :...:|...|..:|.|:....:....:..::...:....:.:|                   ||.
  Fly   362 VVALLLGVVYWQIGGDAQKIVSNVSCLFFVILFVFAGNAMPSILLCMQDSAVFIREYYNGWYSLG 426

  Fly   396 PIWRKKFSQDTPEGLYSGTTLL-IAYNSVSIP--FSAVSAVIASCVVYPLLLDVKYNNGTVFAYL 457
            ..:..|...|.|..|...|..: |.|.....|  |...:...|.||:            |.|...
  Fly   427 AYYLSKVLADLPLQLTCPTMFISIGYFMTGQPPEFQRFAMCWALCVM------------TAFIGH 479

  Fly   458 LVALWSSFVLAEQLTIAFLLVVKVPFNAAIAVTYVLVISIALASGTVRSFKGLQPWLQDNTKGTH 522
            .:.:.:..:...||.|..:....:||              .|.||.......|..:|:.....:.
  Fly   480 FIGVIAGSLFTMQLAIFLVPSATIPF--------------LLFSGFFIRLNELSWFLRPICDVSF 530

  Fly   523 TRYA-SSLLHSI-AFQSRKLNCTPTASVICPKPA-----DFMHE 559
            .||. ..|:.:| .:...:|.|..|::....:.|     ||..|
  Fly   531 FRYIFEGLMRAIYGYDRGELECYATSNFCYYRTAEQFLKDFQME 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	64/192 (33%)
		CcmA	31..302	CDD:224054	87/276 (32%)
		ABC2_membrane	364..515	CDD:304374	27/172 (16%)
CG9664	NP_722889.1	ABCG_EPDR	20..243	CDD:213180	64/192 (33%)
		EcfA2	23..247	CDD:224047	65/196 (33%)
		ABC2_membrane	338..539	CDD:279410	37/233 (16%)
		YadH	<388..547	CDD:223912	31/184 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920