Protein Alignment CG11069 and Abcg2

DIOPT Version :9

• Sequence 1: NP_651307.2
• Gene: CG11069 / 42976
• FlyBaseID: FBgn0039244
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_852046.1
• Gene: Abcg2 / 312382
• RGDID: 631345
• Length: 657
• Species: Rattus norvegicus
• Alignment Length: 595
• Identity: 149/595 - (25%)
• Similarity: 263/595 - (44%)
• Gaps: 80/595 - (13%)

  Fly     9 VLEAHNIFHTTEVDGGGCFNGAGNSALVLKGVNLTVHSGEVMAILGSKGSGKRALLDVISRRAD- 72
            ||..|:|.:..:|..|.......... :|..:|..:..| :.||||..|.||.:||||::.|.|
  Rat    36 VLSFHHITYRVKVKSGFLVRKTAEKE-ILSDINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDP 98

  Fly    73 GATRGQVLLNGSPLSKALFQQRCGYVTQSCTFVPGLTVAQTLHYT-----PTILSGYLKSSKVRQ 132
            ....|.||:||:| ..|.|:...|||.|....:..|||.:.|.::     |..:..:.|:.::..
  Rat    99 RGLSGDVLINGAP-QPANFKCSSGYVVQDDVVMGTLTVRENLQFSAALRLPKAMKTHEKNERINT 162

  Fly   133 VLADLALSQVAHKRV-----EYLNISEARRLAIGIQLVRDPVMLLLDEPTHGLDPLSAYLLISIL 192
            ::.:|.|.:||..:|     ..::..|.:|.:||::|:.||.:|.|||||.|||..:|..::.:|
  Rat   163 IIKELGLDKVADSKVGTQFTRGISGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLL 227

  Fly   193 SNTAKKTGCGILLSLEKPRSDVFPFLDRALFLCLGGVVYSGGTRAMLEYFHGIGFPCPQLENPLM 257
            ...:|: |..|:.|:.:||..:|...|....|..|.:::.|..:..||||...|:.|....||..
  Rat   228 KRMSKQ-GRTIIFSIHQPRYSIFKLFDSLTLLASGKLMFHGPAQKALEYFASAGYHCEPYNNPAD 291

  Fly   258 YYLCLSTVD-------RRSRDRFLESSQQ--------IEALVERFSRETPISD--APLNNMGSGK 305
            ::|.:...|       |..:|.....:::        ||.|.|.:...|...:  |.|:     :
  Rat   292 FFLDVINGDSSAVMLNRGEQDHEANKTEEPSKREKPIIENLAEFYINSTIYGETKAELD-----Q 351

  Fly   306 VPLAYGKPGEL----KVWVMLY---LKLLASTFSCGLVGMKTLFLRLLLLPLALS-ILWAFYTDV 362
            :|:|..|.|..    .|:|..:   |:.:|......|:|.....:..|::.:.|. |:.|.|..:
  Rat   352 LPVAQKKKGSSAFREPVYVTSFCHQLRWIARRSFKNLLGNPQASVAQLIVTVILGLIIGALYFGL 416

  Fly   363 GDDSHGFFTKNGMILNILGLSYGCGILTT---------ISLFPIWRKKFSQDTPEGLYSGTTLLI 418
            .:|..|...:.|:..          .|||         :.||.:.:|.|..:...|.|..::...
  Rat   417 KNDPTGMQNRAGVFF----------FLTTNQCFTSVSAVELFVVEKKLFIHEYISGYYRVSSYFF 471

  Fly   419 AYNSVS--IPFSAVSAVIASCVVYPLLLDVKYNNGTVFAYLLVALWSSFVLAEQLTIAFLLVVKV 481
            . ..||  :|...:.:||.:|::| .:|.:|   .||.|:.::..  :.::......:..|.:..
  Rat   472 G-KLVSDLLPMRFLPSVIYTCLLY-FMLGLK---RTVEAFFIMMF--TLIMVAYTASSMALAIAA 529

  Fly   482 PFNAAIAVTYVLVIS---IALASGTVRSFKGLQPWLQDNTKGTHTRYASSLLHSIAFQSRK---- 539
            ..:.....|.::.||   :.|.||.:.:.:.:.|||......:..||..:.|....|..::
  Rat   530 GQSVVSVATLLMTISFVFMMLFSGLLVNLRTIGPWLSWLQYFSIPRYGFTALQHNEFLGQEFCPG 594

  Fly   540 LNCTPTASVI 549
            ||.|..::.:
  Rat   595 LNVTMNSTCV 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	70/228 (31%)
		CcmA	31..302	CDD:224054	87/298 (29%)
		ABC2_membrane	364..515	CDD:304374	33/164 (20%)
Abcg2	NP_852046.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		3a01204	46..651	CDD:273361	145/585 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820