DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11069 and Abcg3l3

DIOPT Version :9

Sequence 1:	NP_651307.2	Gene:	CG11069 / 42976	FlyBaseID:	FBgn0039244	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_001100675.1	Gene:	Abcg3l3 / 305142	RGDID:	1564709	Length:	647	Species:	Rattus norvegicus

Alignment Length:	507	Identity:	108/507 - (21%)
Similarity:	211/507 - (41%)	Gaps:	91/507 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VLEAHNIFHTTEVDGGGCFNG--------AGNSALVLKGVNLTVHSGEVMAILGSKGSGKRALLD 65
            ||..|||.:...|..|.....        :..|.::..|:|         ||:|.:...:..|||
  Rat    36 VLSFHNISYRETVQSGFPLRQQTHVMERLSSISGIMGPGLN---------AIMGPQDGSRSLLLD 91

  Fly    66 VISRRADG-ATRGQVLLNGSPLSKALFQQRCGYVTQSCTFVPGLTVAQTLHYT-----PTILSGY 124
            |::.|.|. ...|.:|:||.| ..|.|:...|||.|:...:..:||...|.::     |..::..
  Rat    92 VLAARRDPCGLSGDILVNGKP-QPANFKCTSGYVPQNDVIMHTVTVRDNLEFSAALRLPMTITRN 155

  Fly   125 LKSSKVRQVLADLALSQVAHKRVEYLNISEARRLAIGIQLVRDPVMLLLDEPTHGLDPLSAYLLI 189
            .|..::.:||..|.|.:..:.:.....:  .:|.:|.::||.:..:|.||:||.|||..:...:|
  Rat   156 EKRRRINEVLELLHLEKEQNTKPRSKEL--RKRTSIAVELVTEHPILFLDDPTTGLDLRTTTDII 218

  Fly   190 SILSNTAKKTGCGILLSLEKPRSDVFPFLDRALFLCLGGVVYSGGTRAMLEYFHGIGFPCPQLEN 254
            ::|...:|| |..::.|:.:|:..:|.|.|....:..|.:::.|..:..||||...|:......|
  Rat   219 AVLRRMSKK-GRTVIFSINQPQYSIFRFFDSLTLVASGKLMFHGPAQDALEYFTSAGYQYESHNN 282

  Fly   255 PLMYY-------LCLSTVDRRSRDRFLESSQQIEALVERFSRETPISDAPLNNMGSGKVPLAYGK 312
            |..::       ||.:..|....|...:..:::..:.|:.:  ...:.:||::....|:....|:
  Rat   283 PADFFLDVINGGLCDTEEDGHEADEHEDLYERLHQVTEKLA--NMYAQSPLHSDTRAKLDQLLGE 345

  Fly   313 PGELKVWVMLYLKLLASTF------SCGLVGMKTL-----FLRLLLLPLALSILWAFY------- 359
            ..:.:      ...:.:||      ..|.:.:::.     |..:.::...::::.|.:
  Rat   346 QKQDR------RSAMETTFVTPFWHQFGWITLRSFKNFKGFPWVTVIQAIIAVILAVFVGTIFRL 404

  Fly   360 -----TDVGDDSHGFFTKNGMILNILG----LSYGCGILTTISLFPIWRKKFSQDTPEGLYSGTT 415
                 |:|.       .:.|::..:.|    ||...|     .||.:.|..|..:...|.|..::
  Rat   405 LQNVCTEVK-------ARAGLLFFLTGFECILSVSAG-----ELFLLDRNHFLHEHTSGYYRVSS 457

  Fly   416 L----LIAYNSVSIPFSAVSAVIASCVVY---PLLLDVKYNNGTVFAYLLVA 460
            .    |:|   ..||...:.::|.:.:.|   .:...||....|:|..:::|
  Rat   458 YFFGKLLA---ELIPRRLLPSMIFTLITYFIAGMKTGVKGFFVTIFTVMMLA 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	58/231 (25%)
		CcmA	31..302	CDD:224054	70/283 (25%)
		ABC2_membrane	364..515	CDD:304374	22/108 (20%)
Abcg3l3	NP_001100675.1	3a01204	64..644	CDD:273361	101/479 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810