Protein Alignment CG11069 and Abcg4

DIOPT Version :10

• Sequence 1: NP_651307.2
• Gene: CG11069 / 42976
• FlyBaseID: FBgn0039244
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_620405.3
• Gene: Abcg4 / 192663
• MGIID: 1890594
• Length: 646
• Species: Mus musculus
• Alignment Length: 656
• Identity: 145/656 - (22%)
• Similarity: 260/656 - (39%)
• Gaps: 132/656 - (20%)

  Fly     7 DYVLEAHNIFH--------------TTEVDGGGCFNGAGNSALVLKGVNLTVHSGEVMAILGSKG 57
            :::.||....|              :..|..|.|:...|...| ||.::......|::.|:|..|
Mouse    42 NHITEAQRFSHLPKRSAVDIEFVELSYSVREGPCWRKRGYKTL-LKCLSGKFCRRELIGIMGPSG 105

  Fly    58 SGKRALLDVISRRADGATRGQVLLNGSPLSKALFQQRCGYVTQSCTFVPGLTVAQTLHYTPTILS 122
            :||...:::::...:...:||:|:||.|.....|::...|:.|....:|.|||.:.:     ::|
Mouse   106 AGKSTFMNILAGYRESGMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAM-----MVS 165

  Fly   123 GYLKSSK--------VRQVLADLALSQVAHKRVEYLNISEARRLAIGIQLVRDPVMLLLDEPTHG 179
            ..||.|:        |.::|..|.|...:|.|...|:..:.:||||.::||.:|.::..||||.|
Mouse   166 ANLKLSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSG 230

  Fly   180 LDPLSAYLLISILSNTAKKTGCGILLSLEKPRSDVFPFLDRALFLCLGGVVYSGGTRAMLEYFHG 244
            ||..|.:.::|::.:.| ..|..::.::.:|.:.:|...|:...|..|..::.|....::.|..|
Mouse   231 LDSASCFQVVSLMKSLA-HGGRTVICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKG 294

  Fly   245 IGFPCPQLENPLMYYLCLSTVDRRSRDRFLESSQQ--IEALVERFSRETPISDAPLNNMGSGKVP 307
            :|..||...||..:.:.:::.:....:..|..:.|  :..:.|:.|       :|..|......|
Mouse   295 LGLHCPTYHNPADFIIEVASGEYGDLNPMLFRAVQNGLCTMAEKKS-------SPGKNELPAHCP 352

  Fly   308 LAYGKPGELK-----------------VWVMLYLKLLASTFSCGLVGMKTLFLRLLLLPLALSIL 355
            ..   |.||.                 ::...:|.:|..|....|     .|:..:|:.:.:.:|
Mouse   353 TC---PPELDPIESHTFATSTLTQFCILFRRTFLSILRDTVLTHL-----RFMSHVLIGVLIGLL 409

  Fly   356 WAFYTDVGDDSHGFFTKNG-MILNILGLSYGCGILTTISLFPIWRKKFSQDTPEGLYSGTTLLIA 419
               |..:|||:...|...| :..::|.|.: ..::.|:..||:....|.::.....|:.....:|
Mouse   410 ---YLHIGDDASKVFNNTGFLFFSMLFLMF-AALMPTVLTFPLEMAVFMREHLNYWYTLKAYYLA 470

  Fly   420 YNSVSIPFSAVSAVIASCVVYPLLLDVKYNNGTVFAYLLVALW--------SSFVLAEQLTIAFL 476
            .....:||..|..|:...:||                     |        |.|:|...|.||..
Mouse   471 KTMADVPFQVVCPVVYCSIVY---------------------WMTGQPAETSRFLLFSALAIATA 514

  Fly   477 LVVK----------VPFNAAIAVTYVLVISIALASGTVRSFKGLQPWLQDNTKGTHTRYA-SSLL 530
            ||.:          .....|..|..|..|.:.|.||...|||.:..:||.::..::.||. ..|:
Mouse   515 LVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGLI 579

  Fly   531 HSIAFQSR-KLNCTPTASVICPKPADFMHERLGLPDPD---ETIDVAAS------CAFAVGLAAF 585
            .:|....| .|.|              :.|:....||.   ..:||..:      ....:...|.
Mouse   580 LTIYGMERGHLTC--------------LDEQCPFRDPQIILRELDVEEAKLYMDFLVLGIFFLAL 630

  Fly   586 NMLVYL 591
            .:|.||
Mouse   631 RLLAYL 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	61/239 (26%)
		ABC2_membrane	364..515	CDD:473876	37/169 (22%)
Abcg4	NP_620405.3	3a01204	44..646	CDD:273361	145/654 (22%)